GeneInfo:
GeneAttribute
GeneDescription
GeneSymbol
C6orf136
FullNmae
chromosome 6 open reading frame 136
LocusType
gene with protein product
Status
Approved
HGNC_id
HGNC:21301
EnsembleID
ENSG00000204564
Uniprot
Q5SQH8
Protein Structure:
Gene Description in Publicaton:
GeneSymbol
CellDeathType
PMID
Description
GeneType
C6orf136
cuproptosis
36010978
Derived from the genome-wide CRISPR-Cas9 loss-of-function test reported in previous literature, 347 potential cuproptosis-related genes (FDR < 0.05) were identified, and for a detailed list of genes, see聽Supplementary Table S1.
Cuproptosis-related genes
C6ORF136
cuproptosis
38348451
unknown
CRGs in the cuproptosis pathway
Protein-Protein Interaction(String):
Signalink 3.0 modificators
Source
Target
Pmid
Interactiontype
Methods
Database
E2F4
C6ORF136
17531812
trascriptional regulation,stimulation
chromatin immunoprecipitation array
TFlink
ETS1
C6ORF136
20019798
trascriptional regulation,stimulation
chromatin immunoprecipitation assay
TFlink
E2F1
C6ORF136
18971253
trascriptional regulation,stimulation
inferred by curator
TFlink
HNF4A
C6ORF136
18971253
trascriptional regulation,stimulation
inferred by curator
TFlink
Source
Target
Pmid
Interactiontype
Methods
Database
PLK1
C6ORF136
21900206
24234451
25348397
physical association
two hybrid,physical interaction
ComPPI,IntAct
CSNK2B
C6ORF136
21900206
24234451
25348397
physical association
two hybrid,physical interaction
ComPPI,IntAct
Visualization