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GENE：CAPRIN1

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol CAPRIN1
FullNmae cell cycle associated protein 1
LocusType gene with protein product
Status Approved
HGNC_id HGNC:6743
EnsembleID ENSG00000135387
Uniprot Q14444

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
CAPRIN1 cuproptosis 36010978 Derived from the genome-wide CRISPR-Cas9 loss-of-function test reported in previous literature, 347 potential cuproptosis-related genes (FDR < 0.05) were identified, and for a detailed list of genes, see聽Supplementary Table S1. Cuproptosis-related genes

Go Annotation:

GeneSymbol Go id
CAPRIN1 GO:0000932,GO:0003723,GO:0003723,GO:0003723,GO:0003729,GO:0005515,GO:0005524,GO:0005737,GO:0005737,GO:0005829,GO:0010494,GO:0016020,GO:0017148,GO:0017148,GO:0030027,GO:0030154,GO:0030425,GO:0031252,GO:0035591,GO:0043232,GO:0045202,GO:0050775,GO:0061003,GO:0062029,GO:0106288,GO:0140677,GO:0140693,GO:0140694

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
RNF2 CAPRIN1 23180781 24457600 physical association anti tag coimmunoprecipitation InnateDB
BMI1 CAPRIN1 23180781 24457600 physical association anti tag coimmunoprecipitation InnateDB
CAPRIN1 UBB 23180781 24816145 ubiquitination reaction ubiquitinase assay InnateDB
CAPRIN1 PRKRA 23180781 25784705 physical association anti tag coimmunoprecipitation InnateDB
PRKRA CAPRIN1 23180781 25784705 physical association pull down InnateDB

Source Target Pmid Interactiontype Methods Database
ETS1 CAPRIN1 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
HIF1A CAPRIN1 19828020 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
SMARCA4 CAPRIN1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA CAPRIN1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF CAPRIN1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 CAPRIN1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 CAPRIN1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 CAPRIN1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXP1 CAPRIN1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS CAPRIN1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
GATA2 CAPRIN1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF CAPRIN1 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00000EED18 CAPRIN1 21566225 25416803 mrna cleavage,inhibition experimental interaction detection TarBase
URS000009262D CAPRIN1 18591254 25416803 mrna cleavage,inhibition array technology TarBase
URS000002103A CAPRIN1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00001A7F58 CAPRIN1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00005651EE CAPRIN1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000153377 CAPRIN1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000075A9CF CAPRIN1 20371350 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00000C4DB5 CAPRIN1 20371350 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00000B7E30 CAPRIN1 23953883 25416803 mrna cleavage,inhibition western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase
URS000075E2C3 CAPRIN1 20371350 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00004214BB CAPRIN1 20371350 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00002C02E4 CAPRIN1 20371350 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00004977C5 CAPRIN1 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00003E5E03 CAPRIN1 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00003003B4 CAPRIN1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000032BDF4 CAPRIN1 19536157 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000044FD7 CAPRIN1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000029D9F1 CAPRIN1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00001597DC CAPRIN1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000096022 CAPRIN1 19536157 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00000BA274 CAPRIN1 19536157 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00005194EC CAPRIN1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00002CEB74 CAPRIN1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000101787 CAPRIN1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000003575B CAPRIN1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000003E1A9 CAPRIN1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000007D64A CAPRIN1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00001270D3 CAPRIN1 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS00000CBE63 CAPRIN1 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS000041E949 CAPRIN1 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS0000346991 CAPRIN1 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS00005ECFE5 CAPRIN1 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS0000184017 CAPRIN1 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS00000ECE9C CAPRIN1 25416803 27292025 27418678 mrna cleavage,inhibition clip TarBase
URS000024B619 CAPRIN1 25416803 27292025 27418678 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
PIN1 CAPRIN1 25348397 N/A physical interaction ComPPI
FXR2 CAPRIN1 25348397 N/A physical interaction ComPPI
STAT1 CAPRIN1 24234451 25348397 26966684 association pull down ComPPI,IntAct
BMI1 CAPRIN1 25348397 N/A physical interaction ComPPI
NF2 CAPRIN1 25348397 N/A physical interaction ComPPI
JUN CAPRIN1 24234451 25348397 25609649 association anti bait coimmunoprecipitation ComPPI,IntAct
COPS5 CAPRIN1 25348397 N/A physical interaction ComPPI
CUL3 CAPRIN1 25348397 N/A physical interaction ComPPI
NTRK1 CAPRIN1 25348397 N/A physical interaction ComPPI
PRMT1 CAPRIN1 25348397 N/A physical interaction ComPPI
YBX1 CAPRIN1 25348397 N/A physical interaction ComPPI
ILK CAPRIN1 24234451 25348397 25852190 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
RPA1 CAPRIN1 25348397 N/A physical interaction ComPPI
PTPN4 CAPRIN1 24234451 25348397 28330616 association pull down ComPPI,IntAct
CFTR CAPRIN1 17110338 24234451 25348397 association anti bait coimmunoprecipitation ComPPI,IntAct
RPA2 CAPRIN1 25348397 N/A physical interaction ComPPI
RPA3 CAPRIN1 25348397 N/A physical interaction ComPPI
RPS6 CAPRIN1 25348397 N/A physical interaction ComPPI
WBP4 CAPRIN1 16055720 24234451 25348397 physical association pull down,physical interaction ComPPI,IntAct
CDK2 CAPRIN1 25348397 N/A physical interaction ComPPI
CUL1 CAPRIN1 25348397 N/A physical interaction ComPPI
EGFR CAPRIN1 25348397 N/A physical interaction ComPPI
PINX1 CAPRIN1 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
RNF2 CAPRIN1 25348397 N/A physical interaction ComPPI
TSG101 CAPRIN1 25348397 N/A physical interaction ComPPI
VCAM1 CAPRIN1 22623428 24234451 25348397 association cross-linking study ComPPI,IntAct
DNM1L CAPRIN1 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
RPL7 CAPRIN1 25348397 N/A physical interaction ComPPI
CAND1 CAPRIN1 25348397 N/A physical interaction ComPPI
FXR1 CAPRIN1 25348397 N/A physical interaction ComPPI
ESR1 CAPRIN1 21182205 24234451 25348397 association affinity chromatography technology,cosedimentation through density gradient,physical interaction ComPPI,IntAct
RPS6KB2 CAPRIN1 25348397 N/A physical interaction ComPPI
BRCA1 CAPRIN1 25348397 N/A physical interaction ComPPI
GIGYF2 CAPRIN1 25348397 N/A physical interaction ComPPI
CIRBP CAPRIN1 25348397 N/A physical interaction ComPPI
TARDBP CAPRIN1 25348397 N/A physical interaction ComPPI
RRP1B CAPRIN1 20926688 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
IGSF8 CAPRIN1 25348397 N/A physical interaction ComPPI
PHACTR3 CAPRIN1 24234451 25348397 28330616 association pull down ComPPI,IntAct
CAPRIN1 G3BP1 17210633 18005740 24234451 25348397 27898060 colocalization fluorescence technology,physical interaction ComPPI,IntAct,OmniPath
CAPRIN1 SIRT7 25348397 N/A physical interaction ComPPI
CAPRIN1 APP 25348397 N/A physical interaction ComPPI
CAPRIN1 FBXO6 25348397 N/A physical interaction ComPPI
CAPRIN1 STAU1 25348397 N/A physical interaction ComPPI
CAPRIN1 SIRT6 25348397 N/A physical interaction ComPPI
CAPRIN1 HNRNPA1 25348397 N/A physical interaction ComPPI
CAPRIN1 CYLD 25348397 N/A physical interaction ComPPI
CAPRIN1 G3BP2 25348397 N/A physical interaction ComPPI
CAPRIN1 CLEC14A 25348397 N/A physical interaction ComPPI
CAPRIN1 HLA-B 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
CAPRIN1 NXF1 18596238 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
CAPRIN1 MNDA 24234451 25348397 25665578 association anti tag coimmunoprecipitation ComPPI,IntAct
CAPRIN1 NBEAL2 24234451 25348397 29187380 association tandem affinity purification ComPPI,IntAct
CAPRIN1 DAPK1 24234451 25348397 29513927 N/A protein array ComPPI,IntAct
CAPRIN1 MFHAS1 24234451 25348397 29513927 N/A protein array ComPPI,IntAct
CAPRIN1 CAPRIN1 14525934 7657653 N/A experimental interaction detection HPRD
MKI67 CAPRIN1 24234451 26949251 association anti tag coimmunoprecipitation IntAct
DICER1 CAPRIN1 21858095 24234451 association anti tag coimmunoprecipitation IntAct
CAPRIN1 PES1 24234451 30021884 physical association cross-linking study IntAct
CAPRIN1 BNIP5 24234451 30021884 physical association cross-linking study IntAct
RBM25 CAPRIN1 24234451 30021884 physical association cross-linking study IntAct
ABTB1 CAPRIN1 24234451 30021884 physical association cross-linking study IntAct

Source Target Pmid Interactiontype Methods Database
URS00009B44C1 CAPRIN1 27087310 direct interaction,inhibition N/A NPInter

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