GENE:CCDC115
GeneInfo:
| GeneAttribute | GeneDescription |
|---|---|
| GeneSymbol | CCDC115 |
| FullNmae | coiled-coil domain containing 115 |
| LocusType | gene with protein product |
| Status | Approved |
| HGNC_id | HGNC:28178 |
| EnsembleID | ENSG00000136710 |
| Uniprot | Q96NT0 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol | CellDeathType | PMID | Description | GeneType |
|---|---|---|---|---|
| CCDC115 | cuproptosis | 36313717 | The details of ninety-six candidate cuproptosis-related genes involved in the copper homeostasis regulatory pathway, copper metabolism diseases, mitochondrial respiratory, and iron-sulfur cluster proteins were exhibited in Table S1. | Copper metabolism disease related genes |
Go Annotation:
| GeneSymbol | Go id |
|---|---|
| CCDC115 | GO:0005515,GO:0005764,GO:0005768,GO:0005783,GO:0005793,GO:0006879,GO:0007042,GO:0016020,GO:0016471,GO:0030137,GO:0036295,GO:0051082,GO:0070072,GO:1905146 |
Protein-Protein Interaction(String):
Signalink 3.0 modificators
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| AR | CCDC115 | 20610535 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| ESR1 | CCDC115 | 18414489 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| GATA1 | CCDC115 | 19941826 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| GATA2 | CCDC115 | 19941826 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| MYC | CCDC115 | 18414489 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| CEBPA | CCDC115 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CTCF | CCDC115 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOS | CCDC115 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| URS0000324096 | CCDC115 | 18668040 25416803 | mrna cleavage,inhibition | experimental interaction detection,experimental interaction detection,experimental interaction detection | TarBase |
| URS00000ED600 | CCDC115 | 20371350 21572407 22012620 22927820 23446348 23592263 23706177 24398324 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
| URS0000568FF8 | CCDC115 | 20371350 21572407 22012620 22927820 23446348 23592263 23706177 24398324 25416803 26701625 27292025 | mrna cleavage,inhibition | clip | TarBase |
| URS0000453664 | CCDC115 | 20371350 21572407 22012620 22927820 23446348 23592263 23706177 24398324 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
| URS00005586D0 | CCDC115 | 20371350 21572407 22012620 22927820 23446348 23592263 23706177 24398324 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
| URS0000250A40 | CCDC115 | 20371350 21572407 22012620 22927820 23446348 23592263 23706177 24398324 25416803 26701625 27292025 | mrna cleavage,inhibition | clip | TarBase |
| URS00000DDD35 | CCDC115 | 20371350 21572407 22012620 22927820 23446348 23592263 23706177 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
| URS000012930C | CCDC115 | 20371350 21572407 22012620 22927820 23446348 23592263 23706177 24398324 25416803 26701625 27292025 | mrna cleavage,inhibition | clip | TarBase |
| URS00001BCAC5 | CCDC115 | 20371350 21572407 22012620 22927820 23446348 23706177 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
| URS00000292B1 | CCDC115 | 20371350 21572407 22012620 22927820 23446348 23706177 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
| URS00001EB9FC | CCDC115 | 20371350 21572407 23446348 23706177 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000166778 | CCDC115 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000078918 | CCDC115 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000018CD09 | CCDC115 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000170D8B | CCDC115 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| TMEM199 | CCDC115 | 25348397 | N/A | physical interaction | ComPPI |
| TK1 | CCDC115 | 21900206 24234451 25348397 | physical association | two hybrid,physical interaction | ComPPI,IntAct |
| RAB7A | CCDC115 | 24234451 25348397 26496610 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| CANX | CCDC115 | 24234451 25348397 29568061 | association | proximity-dependent biotin identification | ComPPI,IntAct |
| PLK1 | CCDC115 | 21900206 24234451 25348397 | physical association | two hybrid,physical interaction | ComPPI,IntAct |
| PRKCZ | CCDC115 | 21900206 24234451 25348397 | physical association | two hybrid,physical interaction | ComPPI,IntAct |
| ATP6AP2 | CCDC115 | 24234451 25348397 26496610 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| CLTC | CCDC115 | 24234451 25348397 26496610 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| CSNK2B | CCDC115 | 21900206 24234451 25348397 | physical association | two hybrid,physical interaction | ComPPI,IntAct |
| ATP6V0E1 | CCDC115 | 25348397 | N/A | physical interaction | ComPPI |
| NTAQ1 | CCDC115 | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
| ATP6V0D1 | CCDC115 | 25348397 | N/A | physical interaction | ComPPI |
| C3AR1 | CCDC115 | 25348397 | N/A | physical interaction | ComPPI |
| TMEM216 | CCDC115 | 24234451 25348397 26638075 | association | physical interaction,proximity-dependent biotin identification | ComPPI,IntAct |
| ATP6V0A2 | CCDC115 | 25348397 | N/A | physical interaction | ComPPI |
| LAMP1 | CCDC115 | 24234451 25348397 29568061 | association | proximity-dependent biotin identification | ComPPI,IntAct |
| APP | CCDC115 | 25348397 | N/A | physical interaction | ComPPI |
| TSPAN17 | CCDC115 | 25348397 | N/A | physical interaction | ComPPI |
| MUC1 | CCDC115 | 25348397 | N/A | physical interaction | ComPPI |
| PLXDC2 | CCDC115 | 25348397 | N/A | physical interaction | ComPPI |
| GOLT1B | CCDC115 | 24234451 25348397 26496610 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| CCDC115 | TCTN2 | 24234451 25348397 26638075 | association | physical interaction,proximity-dependent biotin identification | ComPPI,IntAct |
| CCDC115 | TCTN3 | 24234451 25348397 26638075 | association | physical interaction,proximity-dependent biotin identification | ComPPI,IntAct |
| CCDC115 | TMEM17 | 24234451 25348397 26638075 | association | physical interaction,proximity-dependent biotin identification | ComPPI,IntAct |
| CCDC115 | TPTE | 25348397 | N/A | physical interaction | ComPPI |
| CCDC115 | ATP6V0D2 | 25348397 | N/A | physical interaction | ComPPI |
| CCDC115 | KIAA2013 | 25348397 | N/A | physical interaction | ComPPI |
