GeneInfo:
GeneAttribute
GeneDescription
GeneSymbol
CCDC137
FullNmae
coiled-coil domain containing 137
LocusType
gene with protein product
Status
Approved
HGNC_id
HGNC:33451
EnsembleID
ENSG00000185298
Uniprot
Q6PK04
Protein Structure:
Gene Description in Publicaton:
GeneSymbol
CellDeathType
PMID
Description
GeneType
CCDC137
cuproptosis
36010978
Derived from the genome-wide CRISPR-Cas9 loss-of-function test reported in previous literature, 347 potential cuproptosis-related genes (FDR < 0.05) were identified, and for a detailed list of genes, see聽Supplementary Table S1.
Cuproptosis-related genes
Go Annotation:
GeneSymbol
Go id
CCDC137
GO:0001650,GO:0003723,GO:0005515,GO:0005634,GO:0005694,GO:0005730
Protein-Protein Interaction(String):
Signalink 3.0 modificators
Source
Target
Pmid
Interactiontype
Methods
Database
ETS1
CCDC137
18971253
20019798
trascriptional regulation,stimulation
inferred by curator,chromatin immunoprecipitation assay
TFlink
SMARCA4
CCDC137
18971253
trascriptional regulation,stimulation
inferred by curator
TFlink
CTCF
CCDC137
18971253
trascriptional regulation,stimulation
inferred by curator
TFlink
E2F4
CCDC137
18971253
trascriptional regulation,stimulation
inferred by curator
TFlink
EGR1
CCDC137
18971253
trascriptional regulation,stimulation
inferred by curator
TFlink
FOXP1
CCDC137
18971253
trascriptional regulation,stimulation
inferred by curator
TFlink
FOS
CCDC137
18971253
trascriptional regulation,stimulation
inferred by curator
TFlink
HNF4A
CCDC137
18971253
trascriptional regulation,stimulation
inferred by curator
TFlink
SPI1
CCDC137
18971253
trascriptional regulation,stimulation
inferred by curator
TFlink
Source
Target
Pmid
Interactiontype
Methods
Database
URS0000338542
CCDC137
18668040
25416803
mrna cleavage,inhibition
experimental interaction detection
TarBase
URS0000070B1D
CCDC137
23622248
25416803
mrna cleavage,inhibition
clash
TarBase
URS00003D5391
CCDC137
23622248
25416803
mrna cleavage,inhibition
clash
TarBase
URS00002075FA
CCDC137
20371350
22473208
25416803
mrna cleavage,inhibition
clip
TarBase
URS000006FDD4
CCDC137
20371350
22473208
25416803
mrna cleavage,inhibition
clip
TarBase
URS0000042E1F
CCDC137
20371350
22473208
25416803
mrna cleavage,inhibition
clip
TarBase
URS00000DDD35
CCDC137
20371350
22473208
25416803
mrna cleavage,inhibition
clip
TarBase
URS000039E1E1
CCDC137
20371350
25416803
mrna cleavage,inhibition
clip
TarBase
URS0000315338
CCDC137
20371350
25416803
mrna cleavage,inhibition
clip
TarBase
URS00000600E6
CCDC137
20371350
22473208
25416803
mrna cleavage,inhibition
clip
TarBase
URS00001C11BC
CCDC137
20371350
25416803
mrna cleavage,inhibition
clip
TarBase
URS00002C0FCB
CCDC137
20371350
25416803
mrna cleavage,inhibition
clip
TarBase
URS00002B3783
CCDC137
20371350
22473208
25416803
mrna cleavage,inhibition
clip
TarBase
URS000037D7E5
CCDC137
20371350
25416803
mrna cleavage,inhibition
clip
TarBase
URS00003883FE
CCDC137
20371350
25416803
mrna cleavage,inhibition
clip
TarBase
URS0000298BA3
CCDC137
20371350
22473208
25416803
mrna cleavage,inhibition
clip
TarBase
URS00003E5ECC
CCDC137
20371350
25416803
mrna cleavage,inhibition
clip
TarBase
URS000075ABF4
CCDC137
20371350
25416803
mrna cleavage,inhibition
clip
TarBase
URS000031602A
CCDC137
20371350
25416803
mrna cleavage,inhibition
clip
TarBase
URS0000251D0B
CCDC137
20371350
25416803
mrna cleavage,inhibition
clip
TarBase
URS00004F2EB0
CCDC137
20371350
25416803
mrna cleavage,inhibition
clip
TarBase
URS0000279B6F
CCDC137
20371350
25416803
mrna cleavage,inhibition
clip
TarBase
URS000015A0D9
CCDC137
20371350
25416803
mrna cleavage,inhibition
clip
TarBase
URS0000047A8F
CCDC137
20371350
25416803
mrna cleavage,inhibition
clip
TarBase
URS0000214763
CCDC137
20371350
25416803
mrna cleavage,inhibition
clip
TarBase
URS000014F13C
CCDC137
20371350
25416803
mrna cleavage,inhibition
clip
TarBase
URS0000284586
CCDC137
20371350
25416803
mrna cleavage,inhibition
clip
TarBase
URS00003003B4
CCDC137
23824327
25416803
mrna cleavage,inhibition
clip
TarBase
URS00000B7E30
CCDC137
23824327
25416803
mrna cleavage,inhibition
clip
TarBase
URS0000101787
CCDC137
23824327
25416803
mrna cleavage,inhibition
clip
TarBase
Source
Target
Pmid
Interactiontype
Methods
Database
NPM1
CCDC137
25348397
N/A
physical interaction
ComPPI
RPL37A
CCDC137
25348397
N/A
physical interaction
ComPPI
SNRNP70
CCDC137
25348397
N/A
physical interaction
ComPPI
HNRNPU
CCDC137
24234451
25348397
26496610
association
anti tag coimmunoprecipitation,physical interaction
ComPPI,IntAct
RPS6
CCDC137
24234451
25348397
29568061
association
proximity-dependent biotin identification
ComPPI,IntAct
SYNCRIP
CCDC137
25348397
N/A
physical interaction
ComPPI
FOXA1
CCDC137
25348397
N/A
physical interaction
ComPPI
NOP56
CCDC137
24234451
25348397
26496610
association
anti tag coimmunoprecipitation,physical interaction
ComPPI,IntAct
MPP3
CCDC137
16169070
24234451
25348397
physical association
two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach
ComPPI,IntAct
TERF2
CCDC137
21044950
24234451
25348397
physical association
pull down,physical interaction,bimolecular fluorescence complementation
ComPPI,IntAct
IFI16
CCDC137
25348397
N/A
physical interaction
ComPPI
RPL14
CCDC137
25348397
N/A
physical interaction
ComPPI
SRPK3
CCDC137
23602568
24234451
25348397
association
physical interaction,tandem affinity purification
ComPPI,IntAct
DGCR8
CCDC137
25348397
N/A
physical interaction
ComPPI
RPS14
CCDC137
25348397
N/A
physical interaction
ComPPI
RPL8
CCDC137
25348397
N/A
physical interaction
ComPPI
RPL30
CCDC137
25348397
N/A
physical interaction
ComPPI
NOP53
CCDC137
25348397
N/A
physical interaction
ComPPI
CCDC137
RBM34
25348397
N/A
physical interaction
ComPPI
CCDC137
WDR46
25348397
N/A
physical interaction
ComPPI
CCDC137
RRP8
25348397
N/A
physical interaction
ComPPI
CCDC137
ZNF2
25348397
N/A
physical interaction
ComPPI
CCDC137
CNBP
25348397
N/A
physical interaction
ComPPI
MKI67
CCDC137
24234451
26949251
association
anti tag coimmunoprecipitation
IntAct
Visualization