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GENE：CDK5RAP1

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol CDK5RAP1
FullNmae CDK5 regulatory subunit associated protein 1
LocusType gene with protein product
Status Approved
HGNC_id HGNC:15880
EnsembleID ENSG00000101391
Uniprot Q96SZ6

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
CDK5RAP1 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
CDK5RAP1 cuproptosis 36685880 A total of 43 CRGs were manually identified and used to investigate the effects of cuproptosis in HNSC in current study. cuproptosis-related genes
CDK5RAP1 cuproptosis 36505872 A total of 44 cuproptosis-related genes were extracted from known literature. cuproptosis-related genes

Go Annotation:

GeneSymbol Go id
CDK5RAP1 GO:0005575,GO:0005654,GO:0005739,GO:0005739,GO:0005829,GO:0005829,GO:0007420,GO:0019901,GO:0035597,GO:0035600,GO:0045664,GO:0045736,GO:0045736,GO:0045736,GO:0045903,GO:0046872,GO:0051539,GO:0070131,GO:0070900

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
AR CDK5RAP1 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 CDK5RAP1 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA1 CDK5RAP1 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA2 CDK5RAP1 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
PRDM14 CDK5RAP1 18971253 20953172 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 CDK5RAP1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA CDK5RAP1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF CDK5RAP1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 CDK5RAP1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 CDK5RAP1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 CDK5RAP1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A CDK5RAP1 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
CDK5RAP1 CDK5 25361965 interaction type N/A PTMCode2
CDK5 CDK5RAP1 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
EXOSC5 CDK5RAP1 15231747 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
BAG3 CDK5RAP1 25348397 N/A physical interaction ComPPI
CDK5R1 CDK5RAP1 10721722 10915792 11882646 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
ZMYND19 CDK5RAP1 25348397 N/A physical interaction ComPPI
WWP2 CDK5RAP1 25348397 N/A physical interaction ComPPI
XRCC5 CDK5RAP1 25348397 N/A physical interaction ComPPI
XRCC6 CDK5RAP1 25348397 N/A physical interaction ComPPI
HNRNPL CDK5RAP1 25348397 N/A physical interaction ComPPI
PDZK1 CDK5RAP1 25348397 N/A physical interaction ComPPI
CDK5 CDK5RAP1 11882646 14525934 25348397 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
CDK5RAP1 EXOSC3 14525934 15231747 24234451 25348397 physical association two hybrid,physical interaction,two hybrid ComPPI,HPRD,IntAct
CDK5RAP1 KCTD17 25348397 N/A physical interaction ComPPI
CDK5RAP1 CARNMT1 25348397 N/A physical interaction ComPPI
CDK5RAP1 KIAA0930 25348397 N/A physical interaction ComPPI
CDK5RAP1 NDUFAF5 25348397 N/A physical interaction ComPPI
CDK5RAP1 PDZK1P1 25348397 N/A physical interaction ComPPI
CDK5RAP1 PLA2G10 25348397 N/A physical interaction ComPPI
CDK5RAP1 ZZEF1 25348397 N/A physical interaction ComPPI
CDK5RAP1 ARMC8 25348397 N/A physical interaction ComPPI
CDK5RAP1 MATR3 25348397 N/A physical interaction ComPPI
CDK5RAP1 RIPK4 24234451 25348397 26972000 association anti tag coimmunoprecipitation ComPPI,IntAct
MGST3 CDK5RAP1 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
TRMT61B CDK5RAP1 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct

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