Gene Information gene info

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GENE：CERT1

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol CERT1
FullNmae ceramide transporter 1
LocusType gene with protein product
Status Approved
HGNC_id HGNC:2205
EnsembleID ENSG00000113163
Uniprot Q9Y5P4

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
CERT1 cuproptosis 36010978 Derived from the genome-wide CRISPR-Cas9 loss-of-function test reported in previous literature, 347 potential cuproptosis-related genes (FDR < 0.05) were identified, and for a detailed list of genes, see聽Supplementary Table S1. Cuproptosis-related genes

Go Annotation:

GeneSymbol Go id
CERT1 GO:0000902,GO:0001701,GO:0003007,GO:0005515,GO:0005654,GO:0005739,GO:0005789,GO:0005794,GO:0005829,GO:0005829,GO:0006672,GO:0006936,GO:0006955,GO:0007029,GO:0007165,GO:0008283,GO:0016301,GO:0034976,GO:0035621,GO:0035627,GO:0048471,GO:0055088,GO:0070584,GO:0097001,GO:0120009,GO:0120012,GO:0120017,GO:1902387,GO:1902388,GO:1902389

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
GATA3 CERT1 21878914 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
FOXA1 CERT1 18971253 21878914 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
PRDM14 CERT1 18971253 20953172 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 CERT1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA CERT1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF CERT1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 CERT1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS CERT1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A CERT1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
RUNX1 CERT1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TAL1 CERT1 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00000011DF CERT1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00002C28B2 CERT1 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000016E46F CERT1 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00001C04A2 CERT1 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000020579D CERT1 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00004C6C6F CERT1 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00000C5BAA CERT1 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00001EE123 CERT1 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS0000334286 CERT1 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00000AD002 CERT1 23446348 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS0000214763 CERT1 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS0000047A8F CERT1 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000075C4B1 CERT1 23446348 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000007F792 CERT1 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00001A6D0C CERT1 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000029D9F1 CERT1 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00003D4175 CERT1 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000027352D CERT1 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00001496AE CERT1 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000040EC3B CERT1 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS000075D15B CERT1 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS00007455B8 CERT1 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS0000243FF1 CERT1 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS00002F3336 CERT1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000298BA3 CERT1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000075C1E1 CERT1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00002A8BC6 CERT1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000032AE90 CERT1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00003E5ECC CERT1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000075A760 CERT1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00002152A8 CERT1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000137EDE CERT1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000019907A CERT1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00001DABC0 CERT1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00000B989F CERT1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00001C770D CERT1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00001067D1 CERT1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000435A77 CERT1 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00000D0874 CERT1 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS0000239117 CERT1 25416803 27292025 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
CSNK1G2 CERT1 22135298 phosphorylation N/A PhosphoSite
PRKD1 CERT1 22135298 phosphorylation N/A PhosphoSite

Source Target Pmid Interactiontype Methods Database
CBSL CERT1 25348397 N/A physical interaction ComPPI
FTL CERT1 25348397 N/A physical interaction ComPPI
CSNK1G2 CERT1 14525934 16189514 24234451 25348397 25416956 physical association two hybrid,physical interaction,two hybrid array,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid prey pooling approach,validated two hybrid,two hybrid ComPPI,HPRD,IntAct
PNMA2 CERT1 25348397 N/A physical interaction ComPPI
TGM2 CERT1 21988832 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
PRKAR1A CERT1 20195357 24234451 25348397 physical association display technology ComPPI,IntAct
ITGB3BP CERT1 14525934 16189514 24234451 25348397 25416956 physical association two hybrid,physical interaction,two hybrid array,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid prey pooling approach,validated two hybrid,two hybrid ComPPI,HPRD,IntAct
PARP2 CERT1 21812934 24234451 25348397 adp ribosylation reaction protein array ComPPI,IntAct
HNRNPL CERT1 25348397 N/A physical interaction ComPPI
PPP2R5C CERT1 25348397 N/A physical interaction ComPPI
RUFY1 CERT1 25348397 N/A physical interaction ComPPI
RANGAP1 CERT1 25348397 N/A physical interaction ComPPI
MARK2 CERT1 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
RTN4 CERT1 14525934 16189514 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
RANBP2 CERT1 25348397 N/A physical interaction ComPPI
MARK3 CERT1 25348397 N/A physical interaction ComPPI
ARL6IP1 CERT1 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
EYA1 CERT1 25348397 N/A physical interaction ComPPI
MARK1 CERT1 25348397 N/A physical interaction ComPPI
RTN3 CERT1 14525934 16189514 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
PACSIN2 CERT1 25348397 N/A physical interaction ComPPI
EXOSC3 CERT1 25348397 N/A physical interaction ComPPI
COL4A3 CERT1 10212244 14525934 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
NAP1L5 CERT1 25348397 N/A physical interaction ComPPI
TRAF7 CERT1 25348397 N/A physical interaction ComPPI
CERT1 POM121 14525934 16189514 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
CERT1 ENTPD7 25348397 N/A physical interaction ComPPI
CBS CERT1 19447967 24234451 25348397 physical association physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach ComPPI,IntAct
ACTL8 CERT1 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
AQP2 CERT1 25348397 N/A physical interaction ComPPI
CERT1 CERT1 14525934 16189514 24234451 25416956 physical association two hybrid array,two hybrid pooling approach,two hybrid HPRD,IntAct
BLVRA CERT1 20177069 27898060 N/A N/A OmniPath
PRKD1 CERT1 17442665 17591919 19005213 21285358 23676904 27898060 inhibition N/A OmniPath
CSNK1G2 CERT1 16189514 19005213 25416956 27898060 inhibition N/A OmniPath
PPM1L CERT1 18165232 27898060 N/A N/A OmniPath
CERT1 COL4A3 10212244 27898060 7768924 N/A N/A OmniPath

Visualization










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