GeneInfo:
GeneAttribute
GeneDescription
GeneSymbol
CHCHD1
FullNmae
coiled-coil-helix-coiled-coil-helix domain containing 1
LocusType
gene with protein product
Status
Approved
HGNC_id
HGNC:23518
EnsembleID
ENSG00000172586
Uniprot
Q96BP2
Protein Structure:
Gene Description in Publicaton:
GeneSymbol
CellDeathType
PMID
Description
GeneType
CHCHD1
cuproptosis
36010978
Derived from the genome-wide CRISPR-Cas9 loss-of-function test reported in previous literature, 347 potential cuproptosis-related genes (FDR < 0.05) were identified, and for a detailed list of genes, see聽Supplementary Table S1.
Cuproptosis-related genes
Go Annotation:
GeneSymbol
Go id
CHCHD1
GO:0001650,GO:0003723,GO:0005515,GO:0005654,GO:0005654,GO:0005739,GO:0005739,GO:0005743,GO:0005743,GO:0005763,GO:0005829,GO:0032543
Protein-Protein Interaction(String):
Signalink 3.0 modificators
Source
Target
Pmid
Interactiontype
Methods
Database
ETS1
CHCHD1
18971253
20019798
trascriptional regulation,stimulation
inferred by curator,chromatin immunoprecipitation assay
TFlink
HIF1A
CHCHD1
19828020
trascriptional regulation,stimulation
chromatin immunoprecipitation array
TFlink
SMARCA4
CHCHD1
18971253
trascriptional regulation,stimulation
inferred by curator
TFlink
CEBPA
CHCHD1
18971253
trascriptional regulation,stimulation
inferred by curator
TFlink
E2F4
CHCHD1
18971253
trascriptional regulation,stimulation
inferred by curator
TFlink
FOS
CHCHD1
18971253
trascriptional regulation,stimulation
inferred by curator
TFlink
Source
Target
Pmid
Interactiontype
Methods
Database
CBY1
CHCHD1
24234451
25348397
27173435
association,physical association
physical interaction,tandem affinity purification,inference by socio-affinity scoring
ComPPI,IntAct
SDCBP2
CHCHD1
24234451
25348397
physical association
two hybrid,two hybrid array,two hybrid prey pooling approach
ComPPI,IntAct
PDK3
CHCHD1
24234451
25348397
27499296
association
anti tag coimmunoprecipitation
ComPPI,IntAct
MESD
CHCHD1
24234451
25348397
physical association
two hybrid,two hybrid array,two hybrid prey pooling approach
ComPPI,IntAct
SLC25A5
CHCHD1
24234451
25348397
27499296
association
anti tag coimmunoprecipitation
ComPPI,IntAct
NEDD1
CHCHD1
25348397
N/A
physical interaction
ComPPI
IDE
CHCHD1
25348397
N/A
physical interaction
ComPPI
ATAD3B
CHCHD1
24234451
25348397
27499296
association
anti tag coimmunoprecipitation
ComPPI,IntAct
CHCHD1
PPM1K
25348397
N/A
physical interaction
ComPPI
CHCHD1
MSRB2
24234451
25348397
27499296
association
anti tag coimmunoprecipitation
ComPPI,IntAct
Visualization