Gene Information gene info

GENE:CIAO2A

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol CIAO2A
FullNmae cytosolic iron-sulfur assembly component 2A
LocusType gene with protein product
Status Approved
HGNC_id HGNC:26235
EnsembleID ENSG00000166797
Uniprot Q9H5X1

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
CIAO2A cuproptosis 36313717 The details of ninety-six candidate cuproptosis-related genes involved in the copper homeostasis regulatory pathway, copper metabolism diseases, mitochondrial respiratory, and iron-sulfur cluster proteins were exhibited in聽Table S1. Genes of iron-sulfur cluster related proteins
CIAO2A cuproptosis 36010978 Derived from the genome-wide CRISPR-Cas9 loss-of-function test reported in previous literature, 347 potential cuproptosis-related genes (FDR < 0.05) were identified, and for a detailed list of genes, see聽Supplementary Table S1. Cuproptosis-related genes

Go Annotation:

GeneSymbol Go id
CIAO2A GO:0005515,GO:0005654,GO:0005829,GO:0007059,GO:0016226,GO:0046872,GO:0097361,GO:0097428,GO:0106035

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
AR CIAO2A 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 CIAO2A 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 CIAO2A 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF CIAO2A 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 CIAO2A 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 CIAO2A 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 CIAO2A 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS CIAO2A 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A CIAO2A 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF CIAO2A 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000324096 CIAO2A N/A rna interference,inhibition experimental interaction detection miRSponge
URS0000324096 CIAO2A 18668040 25416803 mrna cleavage,inhibition experimental interaction detection,experimental interaction detection,experimental interaction detection TarBase
URS00000ED600 CIAO2A 20215506 25416803 mrna cleavage,inhibition array technology TarBase
URS0000065D58 CIAO2A 18668040 25416803 mrna cleavage,inhibition experimental interaction detection TarBase
URS00001CC4BD CIAO2A 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000033EBB8 CIAO2A 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000236310 CIAO2A 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000018C928 CIAO2A 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000272039 CIAO2A 23313552 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000040EC3B CIAO2A 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS0000259AE4 CIAO2A 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS0000100748 CIAO2A 23313552 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
CIAO1 CIAO2A 14525934 16189514 24234451 25348397 25416956 physical association two hybrid,physical interaction,two hybrid array,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid prey pooling approach,validated two hybrid,two hybrid ComPPI,HPRD,IntAct
APOA2 CIAO2A 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
POLE CIAO2A 25348397 N/A physical interaction ComPPI
AGTRAP CIAO2A 25348397 N/A physical interaction ComPPI
TOP3B CIAO2A 25348397 N/A physical interaction ComPPI
VAMP3 CIAO2A 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
PLP2 CIAO2A 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
PRPS2 CIAO2A 25348397 N/A physical interaction ComPPI
DERL1 CIAO2A 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
DNAJB6 CIAO2A 25348397 N/A physical interaction ComPPI
TNFRSF10D CIAO2A 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
EBAG9 CIAO2A 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
CIAO2A IREB2 25348397 N/A physical interaction ComPPI
CIAO2A MLF2 25348397 N/A physical interaction ComPPI
CIAO2A LIME1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
CIAO2A PRAF2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
CIAO2A CREB3L1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct

Visualization