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GENE：CIAPIN1

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol CIAPIN1
FullNmae cytokine induced apoptosis inhibitor 1
LocusType gene with protein product
Status Approved
HGNC_id HGNC:28050
EnsembleID ENSG00000005194
Uniprot Q6FI81

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
CIAPIN1 cuproptosis 36313717 Proteins carrying iron-sulfur clusters are essential for the basic metabolism of all organisms. Eukaryotic iron-sulfur cluster assembly includes direct mitochondrial iron-sulfur cluster (ISC) co-assembly pathway and cytosolic iron-sulfur cluster assembly (CIA) pathway that uses active sulfur as substrate, these pathways containing protein complex (composed of cysteine desulfurase, a scaffold protein, auxiliary ISD11 protein, acyl carrier protein, frataxin, and ferredoxin), the related genes (including NFS1, ISD11, ACP1, ISCU2, FXN, FDX2, FDXR) and proteins of cytokine induced apoptosis inhibitor 1 (CIAPIN1), novel diflavin oxidoreductase 1 (NDOR1), nucleotide binding protein 2 (NUBP2), nucleotide binding protein 1 (NUBP1), iron-only hydrogenase-like protein 1 (IOP1), and Cytosolic iron-Sulfur assembly component 1 (CIAO1) Proteins carrying iron-sulfur cluster
CIAPIN1 cuproptosis 36313717 The details of ninety-six candidate cuproptosis-related genes involved in the copper homeostasis regulatory pathway, copper metabolism diseases, mitochondrial respiratory, and iron-sulfur cluster proteins were exhibited in聽Table S1. Genes of iron-sulfur cluster related proteins

Go Annotation:

GeneSymbol Go id
CIAPIN1 GO:0005506,GO:0005515,GO:0005654,GO:0005730,GO:0005737,GO:0005737,GO:0005737,GO:0005739,GO:0005758,GO:0006915,GO:0008757,GO:0009055,GO:0016226,GO:0022900,GO:0030097,GO:0043066,GO:0051537,GO:0051539

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
ETS1 CIAPIN1 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
YBX1 CIAPIN1 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 CIAPIN1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF CIAPIN1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
GATA2 CIAPIN1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A CIAPIN1 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000338542 CIAPIN1 20584899 rna interference,inhibition experimental interaction detection miRSponge
URS0000338542 CIAPIN1 20584899 22473208 25416803 mrna cleavage,inhibition experimental interaction detection,clip TarBase
URS00000CF1D2 CIAPIN1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00000AA464 CIAPIN1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00003E5ECC CIAPIN1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000014F13C CIAPIN1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000279B6F CIAPIN1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00004DA9DB CIAPIN1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00001DA458 CIAPIN1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000005E58C CIAPIN1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000153377 CIAPIN1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000170CF4 CIAPIN1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000045E0EC CIAPIN1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00001EB9FC CIAPIN1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00000C4DB5 CIAPIN1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000023BE29 CIAPIN1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000075A760 CIAPIN1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00002152A8 CIAPIN1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00001C770D CIAPIN1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000235862 CIAPIN1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000017EA6A CIAPIN1 23592263 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
RNF40 CIAPIN1 25348397 N/A physical interaction ComPPI
AIMP2 CIAPIN1 25348397 N/A physical interaction ComPPI
ZNRD2 CIAPIN1 25348397 N/A physical interaction ComPPI
GLRX3 CIAPIN1 14525934 16189514 21516116 24234451 25348397 25416956 physical association anti tag coimmunoprecipitation,two hybrid,molecular sieving,nuclear magnetic resonance,physical interaction,mammalian protein protein interaction trap,two hybrid array,two hybrid pooling approach,two hybrid fragment pooling approach,bimolecular fluorescence complementation,two hybrid prey pooling approach,validated two hybrid,two hybrid ComPPI,HPRD,IntAct
BOLA1 CIAPIN1 25348397 N/A physical interaction ComPPI
STAT1 CIAPIN1 25348397 N/A physical interaction ComPPI
EGLN3 CIAPIN1 24234451 25348397 26972000 association anti tag coimmunoprecipitation ComPPI,IntAct
HSPB8 CIAPIN1 25348397 N/A physical interaction ComPPI
RBM8A CIAPIN1 25348397 N/A physical interaction ComPPI
CDH1 CIAPIN1 25348397 N/A physical interaction ComPPI
CAPZA1 CIAPIN1 25348397 N/A physical interaction ComPPI
EWSR1 CIAPIN1 25348397 N/A physical interaction ComPPI
RAB5B CIAPIN1 25348397 N/A physical interaction ComPPI
EPRS1 CIAPIN1 25348397 N/A physical interaction ComPPI
RANBP1 CIAPIN1 25348397 N/A physical interaction ComPPI
CUL2 CIAPIN1 25348397 N/A physical interaction ComPPI
YAP1 CIAPIN1 25348397 N/A physical interaction ComPPI
GDA CIAPIN1 25348397 N/A physical interaction ComPPI
UBA1 CIAPIN1 25348397 N/A physical interaction ComPPI
TWF1 CIAPIN1 25348397 N/A physical interaction ComPPI
KARS1 CIAPIN1 25348397 N/A physical interaction ComPPI
CACNB3 CIAPIN1 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
PPP1R2 CIAPIN1 25348397 N/A physical interaction ComPPI
NMD3 CIAPIN1 25348397 N/A physical interaction ComPPI
NDOR1 CIAPIN1 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
RGS20 CIAPIN1 25348397 N/A physical interaction ComPPI
UCHL5 CIAPIN1 25348397 N/A physical interaction ComPPI
EEF1E1 CIAPIN1 25348397 N/A physical interaction ComPPI
AARS1 CIAPIN1 25348397 N/A physical interaction ComPPI
MSH2 CIAPIN1 25348397 N/A physical interaction ComPPI
CIAPIN1 ENY2 25348397 N/A physical interaction ComPPI
CIAPIN1 IKBKG 25348397 N/A physical interaction ComPPI
CIAPIN1 AIMP1 25348397 N/A physical interaction ComPPI
CIAPIN1 PLEKHA7 24234451 25348397 28877994 association anti bait coimmunoprecipitation ComPPI,IntAct
RNF20 CIAPIN1 25348397 N/A physical interaction ComPPI
ATP6V1B2 CIAPIN1 25348397 N/A physical interaction ComPPI

Visualization










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