Gene Information gene info

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GENE：CIT

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol CIT
FullNmae citron rho-interacting serine/threonine kinase
LocusType gene with protein product
Status Approved
HGNC_id HGNC:1985
EnsembleID ENSG00000122966
Uniprot O14578

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
CIT mitotic_cd 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
CIT cuproptosis 36010978 Derived from the genome-wide CRISPR-Cas9 loss-of-function test reported in previous literature, 347 potential cuproptosis-related genes (FDR < 0.05) were identified, and for a detailed list of genes, see聽Supplementary Table S1. Cuproptosis-related genes

Go Annotation:

GeneSymbol Go id
CIT GO:0000278,GO:0000281,GO:0001223,GO:0004674,GO:0005515,GO:0005524,GO:0005829,GO:0005829,GO:0016020,GO:0016310,GO:0017124,GO:0019901,GO:0030165,GO:0030291,GO:0032467,GO:0035331,GO:0046872,GO:0048699,GO:0051402,GO:0097110,GO:0106310

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
EZH2 CIT 23180781 24457600 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
DLG4 CIT 20005715 interaction type N/A PSP

Source Target Pmid Interactiontype Methods Database
AR CIT 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 CIT 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA1 CIT 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA2 CIT 18971253 19941826 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 CIT 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF CIT 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 CIT 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 CIT 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 CIT 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 CIT 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS CIT 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A CIT 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF CIT 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00000F31F4 CIT 19074876 25416803 mrna cleavage,inhibition array technology TarBase
URS00000B59A2 CIT 19074876 25416803 mrna cleavage,inhibition array technology TarBase
URS00000DDD35 CIT 22473208 23622248 25416803 mrna cleavage,inhibition clip,clash TarBase
URS00001A7F58 CIT 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000042E1F CIT 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS00000600E6 CIT 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS00004DA9DB CIT 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS0000482389 CIT 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS000008931A CIT 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS000006FDD4 CIT 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS0000298BA3 CIT 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS00002075FA CIT 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS00002B3783 CIT 22473208 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
CIT MYL9 22135298 phosphorylation N/A PhosphoSite
CIT DLG4 25361965 interaction type N/A PTMCode2
DLG4 CIT 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
RAC1 CIT 25348397 N/A physical interaction ComPPI
DLG4 CIT 14525934 25348397 9870942 N/A two hybrid,experimental interaction detection,in vivo,two hybrid ComPPI,HPRD
EZH2 CIT 25348397 N/A physical interaction ComPPI
RHOB CIT 25348397 N/A physical interaction ComPPI
RHOC CIT 14525934 25348397 8543060 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,two hybrid ComPPI,HPRD
CIT GRIN2D 10862698 14525934 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
CIT GRIN1 10862698 14525934 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
CIT RND3 25348397 N/A physical interaction ComPPI
CIT DISC1 12506198 14525934 25348397 N/A physical interaction,two hybrid ComPPI,HPRD
CIT ELAVL1 25348397 N/A physical interaction ComPPI
CIT HGS 25348397 N/A physical interaction ComPPI
CIT ZNF706 25348397 N/A physical interaction ComPPI
CIT USP28 25348397 N/A physical interaction ComPPI
CIT HECW2 25348397 N/A physical interaction ComPPI
CIT CUL7 25348397 N/A physical interaction ComPPI
CIT OBSL1 25348397 N/A physical interaction ComPPI
CIT ANLN 25348397 N/A physical interaction ComPPI
CIT MTNR1A 24234451 25348397 26514267 physical association two hybrid,physical interaction ComPPI,IntAct
CIT CYLD 25348397 N/A physical interaction ComPPI
CIT RPAP3 25348397 N/A physical interaction ComPPI
CIT G3BP1 25348397 N/A physical interaction ComPPI
CIT WWC1 25348397 N/A physical interaction ComPPI
CIT LNX1 25348397 N/A physical interaction ComPPI
CIT MYL12A 21457715 24234451 25348397 phosphorylation reaction protein kinase assay ComPPI,IntAct
CIT ANG 24234451 25348397 28777577 association anti bait coimmunoprecipitation ComPPI,IntAct
RHOA CIT 14525934 25348397 8543060 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,two hybrid ComPPI,HPRD
CIT RANBP9 19790105 27898060 N/A N/A OmniPath
RHOA CIT 12773565 17332740 27898060 8543060 stimulant N/A OmniPath
ARHGAP1 CIT 27898060 9697773 stimulant N/A OmniPath

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