GeneInfo:
GeneAttribute
GeneDescription
GeneSymbol
CLUH
FullNmae
clustered mitochondria homolog
LocusType
gene with protein product
Status
Approved
HGNC_id
HGNC:29094
EnsembleID
ENSG00000132361
Uniprot
O75153
Protein Structure:
Gene Description in Publicaton:
GeneSymbol
CellDeathType
PMID
Description
GeneType
CLUH
cuproptosis
36010978
Derived from the genome-wide CRISPR-Cas9 loss-of-function test reported in previous literature, 347 potential cuproptosis-related genes (FDR < 0.05) were identified, and for a detailed list of genes, see聽Supplementary Table S1.
Cuproptosis-related genes
Go Annotation:
GeneSymbol
Go id
CLUH
GO:0003729,GO:0003729,GO:0005737,GO:0005737,GO:0007005,GO:0048312,GO:0048312
Protein-Protein Interaction(String):
Signalink 3.0 modificators
Source
Target
Pmid
Interactiontype
Methods
Database
ETS1
CLUH
18971253
20019798
trascriptional regulation,stimulation
inferred by curator,chromatin immunoprecipitation assay
TFlink
GATA2
CLUH
19941826
trascriptional regulation,stimulation
chromatin immunoprecipitation assay
TFlink
PRDM14
CLUH
18971253
20953172
trascriptional regulation,stimulation
inferred by curator,chromatin immunoprecipitation assay
TFlink
SMARCA4
CLUH
18971253
trascriptional regulation,stimulation
inferred by curator
TFlink
CEBPA
CLUH
18971253
trascriptional regulation,stimulation
inferred by curator
TFlink
CTCF
CLUH
18971253
trascriptional regulation,stimulation
inferred by curator
TFlink
E2F1
CLUH
18971253
trascriptional regulation,stimulation
inferred by curator
TFlink
E2F4
CLUH
18971253
trascriptional regulation,stimulation
inferred by curator
TFlink
EGR1
CLUH
18971253
trascriptional regulation,stimulation
inferred by curator
TFlink
HIF1A
CLUH
18971253
trascriptional regulation,stimulation
inferred by curator
TFlink
HNF4A
CLUH
18971253
trascriptional regulation,stimulation
inferred by curator
TFlink
Source
Target
Pmid
Interactiontype
Methods
Database
URS0000122ED0
CLUH
19088304
25416803
mrna cleavage,inhibition
array technology
TarBase
URS0000324096
CLUH
18668040
23622248
25416803
mrna cleavage,inhibition
experimental interaction detection,clash
TarBase
URS00000EC1BE
CLUH
23622248
25416803
mrna cleavage,inhibition
clash
TarBase
URS00005651EE
CLUH
23622248
25416803
mrna cleavage,inhibition
clash
TarBase
URS00003CF1AD
CLUH
23622248
25416803
mrna cleavage,inhibition
clash
TarBase
URS00000157F5
CLUH
25416803
26701625
mrna cleavage,inhibition
clip
TarBase
URS000029979D
CLUH
25416803
26701625
mrna cleavage,inhibition
clip
TarBase
URS0000171CD1
CLUH
25416803
26701625
mrna cleavage,inhibition
clip
TarBase
URS000041CB9C
CLUH
25416803
26701625
mrna cleavage,inhibition
clip
TarBase
URS000009A9A2
CLUH
25416803
26701625
mrna cleavage,inhibition
clip
TarBase
URS000040EE1D
CLUH
25416803
26701625
mrna cleavage,inhibition
clip
TarBase
URS0000081D1E
CLUH
25416803
26701625
mrna cleavage,inhibition
clip
TarBase
URS0000157FBE
CLUH
25416803
26701625
mrna cleavage,inhibition
clip
TarBase
URS00002394F5
CLUH
25416803
26701625
mrna cleavage,inhibition
clip
TarBase
URS000007A060
CLUH
25416803
26701625
mrna cleavage,inhibition
clip
TarBase
URS00001310DE
CLUH
25416803
26701625
mrna cleavage,inhibition
clip
TarBase
URS000057FDB8
CLUH
25416803
26701625
mrna cleavage,inhibition
clip
TarBase
URS00000F0F49
CLUH
25416803
26701625
mrna cleavage,inhibition
clip
TarBase
URS00002578DA
CLUH
25416803
26701625
mrna cleavage,inhibition
clip
TarBase
URS000007D64A
CLUH
25416803
26701625
mrna cleavage,inhibition
clip
TarBase
URS000017EA6A
CLUH
25416803
26701625
mrna cleavage,inhibition
clip
TarBase
URS000075BDAA
CLUH
25416803
26701625
mrna cleavage,inhibition
clip
TarBase
URS0000246356
CLUH
25416803
26701625
mrna cleavage,inhibition
clip
TarBase
Source
Target
Pmid
Interactiontype
Methods
Database
ARPC3
CLUH
25348397
N/A
physical interaction
ComPPI
MOS
CLUH
25348397
N/A
physical interaction
ComPPI
UBL7
CLUH
25348397
N/A
physical interaction
ComPPI
APPL1
CLUH
25348397
N/A
physical interaction
ComPPI
DYNC1LI1
CLUH
25348397
N/A
physical interaction
ComPPI
NTRK1
CLUH
25348397
N/A
physical interaction
ComPPI
HDLBP
CLUH
25348397
N/A
physical interaction
ComPPI
MTUS1
CLUH
25348397
N/A
physical interaction
ComPPI
CYFIP1
CLUH
25348397
N/A
physical interaction
ComPPI
NCKAP1
CLUH
25348397
N/A
physical interaction
ComPPI
MCM4
CLUH
25348397
N/A
physical interaction
ComPPI
CELSR3
CLUH
12421765
14525934
24234451
25348397
physical association
two hybrid,two hybrid
ComPPI,HPRD,IntAct
GKAP1
CLUH
24234451
25348397
physical association
physical interaction,inference by socio-affinity scoring
ComPPI,IntAct
CLUH
SIRT7
25348397
N/A
physical interaction
ComPPI
CLUH
MCM7
25348397
N/A
physical interaction
ComPPI
CLUH
NDUFA10
25348397
N/A
physical interaction
ComPPI
CLUH
ABCF2
25348397
N/A
physical interaction
ComPPI
CLUH
ERCC2
25348397
N/A
physical interaction
ComPPI
CLUH
PFKFB3
25348397
N/A
physical interaction
ComPPI
CLUH
DCAF4
25348397
N/A
physical interaction
ComPPI
CLUH
RIPK4
24234451
25348397
26972000
association
anti tag coimmunoprecipitation
ComPPI,IntAct
Visualization