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GENE：CMPK1

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol CMPK1
FullNmae cytidine/uridine monophosphate kinase 1
LocusType gene with protein product
Status Approved
HGNC_id HGNC:18170
EnsembleID ENSG00000162368
Uniprot P30085

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
CMPK1 cuproptosis 36010978 Derived from the genome-wide CRISPR-Cas9 loss-of-function test reported in previous literature, 347 potential cuproptosis-related genes (FDR < 0.05) were identified, and for a detailed list of genes, see聽Supplementary Table S1. Cuproptosis-related genes

Go Annotation:

GeneSymbol Go id
CMPK1 GO:0004127,GO:0004550,GO:0004849,GO:0005524,GO:0005634,GO:0005654,GO:0005730,GO:0005737,GO:0005829,GO:0006207,GO:0006222,GO:0006225,GO:0006225,GO:0009220,GO:0015949,GO:0016310,GO:0033862,GO:0033862,GO:0036430,GO:0036431,GO:0046705,GO:0046940,GO:0050145,GO:0070062

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
CMPK1 hsa:51727 path:hsa00240 Pyrimidine metabolism - Homo sapiens (human)
CMPK1 hsa:51727 path:hsa00983 Drug metabolism - other enzymes - Homo sapiens (human)
CMPK1 hsa:51727 path:hsa01100 Metabolic pathways - Homo sapiens (human)
CMPK1 hsa:51727 path:hsa01232 Nucleotide metabolism - Homo sapiens (human)
CMPK1 hsa:51727 path:hsa01240 Biosynthesis of cofactors - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
CMPK1 ELAVL1 19322201 23180781 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
ETS1 CMPK1 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA2 CMPK1 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 CMPK1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA CMPK1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF CMPK1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 CMPK1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 CMPK1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A CMPK1 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00001EFEC1 CMPK1 20371350 25416803 mrna cleavage,inhibition nucleotide sequence identification TarBase
URS0000272039 CMPK1 20371350 25416803 mrna cleavage,inhibition nucleotide sequence identification TarBase
URS00000F31F4 CMPK1 19074876 25416803 mrna cleavage,inhibition array technology TarBase
URS00000EED18 CMPK1 21566225 25416803 mrna cleavage,inhibition experimental interaction detection TarBase
URS000016D2D4 CMPK1 20371350 21572407 23446348 25416803 mrna cleavage,inhibition nucleotide sequence identification,clip TarBase
URS00000B59A2 CMPK1 19074876 25416803 mrna cleavage,inhibition array technology TarBase
URS000003ABC4 CMPK1 19088304 25416803 mrna cleavage,inhibition array technology TarBase
URS00005651EE CMPK1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00002075FA CMPK1 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS0000042E1F CMPK1 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS00000DDD35 CMPK1 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS00000600E6 CMPK1 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS00002C0FCB CMPK1 25416803 28414100 mrna cleavage,inhibition western blot TarBase
URS00002B3783 CMPK1 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS000037D7E5 CMPK1 20371350 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00003883FE CMPK1 20371350 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS0000298BA3 CMPK1 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS00004AC389 CMPK1 20371350 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS0000070CD2 CMPK1 20371350 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS0000346991 CMPK1 20371350 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000027080C CMPK1 20371350 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000041E949 CMPK1 20371350 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS0000508C13 CMPK1 20371350 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000015A0D9 CMPK1 20371350 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS0000008A99 CMPK1 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS0000527B00 CMPK1 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS0000122F23 CMPK1 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000036AFF1 CMPK1 20371350 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00000A057E CMPK1 20371350 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00000D5FFC CMPK1 20371350 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00003677B2 CMPK1 20371350 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000031F6C2 CMPK1 20371350 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS0000535FDD CMPK1 20371350 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00001067D1 CMPK1 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000004203C CMPK1 21572407 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
EIF1B CMPK1 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
SGTB CMPK1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
YWHAZ CMPK1 15161933 24234451 25348397 physical association pull down ComPPI,IntAct
EIF6 CMPK1 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
TNIK CMPK1 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
TTC19 CMPK1 25348397 N/A physical interaction ComPPI
TRIM25 CMPK1 25348397 N/A physical interaction ComPPI
ELAVL1 CMPK1 25348397 N/A physical interaction ComPPI
BACE1 CMPK1 14525934 15606899 25348397 N/A two hybrid,two hybrid ComPPI,HPRD
CIDEB CMPK1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
PRKAB1 CMPK1 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
CMPK1 MOV10 25348397 N/A physical interaction ComPPI
CMPK1 NXF1 25348397 N/A physical interaction ComPPI
CMPK1 ACOT13 25348397 N/A physical interaction ComPPI
CMPK1 ETFA 25348397 N/A physical interaction ComPPI
CMPK1 ECE2 25348397 N/A physical interaction ComPPI
CMPK1 NIT2 25348397 N/A physical interaction ComPPI
CMPK1 TATDN1 25348397 N/A physical interaction ComPPI
CMPK1 MCC 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
CMPK1 ATG5 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
CMPK1 KSR1 24234451 25348397 27086506 association anti tag coimmunoprecipitation ComPPI,IntAct
HSCB CMPK1 24234451 25348397 28380382 association anti bait coimmunoprecipitation ComPPI,IntAct

Visualization










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