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GENE：COA5

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol COA5
FullNmae cytochrome c oxidase assembly factor 5
LocusType gene with protein product
Status Approved
HGNC_id HGNC:33848
EnsembleID ENSG00000183513
Uniprot Q86WW8

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
COA5 cuproptosis 36010978 Derived from the genome-wide CRISPR-Cas9 loss-of-function test reported in previous literature, 347 potential cuproptosis-related genes (FDR < 0.05) were identified, and for a detailed list of genes, see聽Supplementary Table S1. Cuproptosis-related genes

Go Annotation:

GeneSymbol Go id
COA5 GO:0005515,GO:0005739,GO:0033617

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
COA5 hsa:493753 path:hsa04714 Thermogenesis - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
GATA2 COA5 18971253 19941826 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
FOXP3 COA5 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
CEBPA COA5 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF COA5 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 COA5 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ETS1 COA5 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00002FF522 COA5 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS0000137EDE COA5 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS000019907A COA5 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS0000195F5B COA5 22012620 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
KRT31 COA5 24234451 25348397 25416956 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
COA5 APP 25348397 N/A physical interaction ComPPI
COA5 PTBP3 22575643 24234451 25348397 association anti bait coimmunoprecipitation ComPPI,IntAct

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