Gene Information gene info

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GENE：NCS1

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol NCS1
FullNmae neuronal calcium sensor 1
LocusType gene with protein product
Status Approved
HGNC_id HGNC:3953
EnsembleID ENSG00000107130
Uniprot P62166

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
NCS1 necroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
NCS1 mitotic_cd 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
NCS1 GO:0005245,GO:0005509,GO:0005509,GO:0005515,GO:0005737,GO:0005794,GO:0005886,GO:0008048,GO:0010975,GO:0014069,GO:0030424,GO:0030425,GO:0043231,GO:0048471,GO:0070588

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
AR NCS1 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 NCS1 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA1 NCS1 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA2 NCS1 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
CEBPA NCS1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF NCS1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 NCS1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 NCS1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 NCS1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS NCS1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A NCS1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TRIM28 NCS1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ZNF263 NCS1 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000521626 NCS1 17612493 25416803 mrna cleavage,inhibition array technology TarBase
URS0000028BB8 NCS1 17612493 25416803 mrna cleavage,inhibition array technology TarBase
URS00000EC1BE NCS1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00005651EE NCS1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00001597DC NCS1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000007A060 NCS1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000214763 NCS1 23592263 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000047A8F NCS1 23592263 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00000254A6 NCS1 23592263 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00004AD450 NCS1 23592263 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000029D793 NCS1 23592263 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00001067D1 NCS1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00001C85C7 NCS1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00002FAA8C NCS1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000032BDF4 NCS1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000585553 NCS1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00000BE495 NCS1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000453664 NCS1 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS0000298BA3 NCS1 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS00002EF20A NCS1 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000014F13C NCS1 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000383DF4 NCS1 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00002394F5 NCS1 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00004C6C6F NCS1 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00001CE046 NCS1 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000334286 NCS1 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000156390 NCS1 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00002E177F NCS1 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000209F04 NCS1 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00003AD2AA NCS1 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00000A9FB9 NCS1 25416803 28735896 mrna cleavage,inhibition clip TarBase
URS00002B7450 NCS1 25416803 28735896 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
SNRPB NCS1 25348397 N/A physical interaction ComPPI
C1QTNF2 NCS1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
TK1 NCS1 25348397 N/A physical interaction ComPPI
FCGR3A NCS1 25348397 N/A physical interaction ComPPI
SPRED2 NCS1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
SPP1 NCS1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
HNRNPL NCS1 25348397 N/A physical interaction ComPPI
KCND2 NCS1 11606724 14525934 25348397 27898060 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD,OmniPath
XPO1 NCS1 25348397 N/A physical interaction ComPPI
GRK2 NCS1 12351722 14525934 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
DRD3 NCS1 12351722 14525934 25348397 N/A two hybrid,experimental interaction detection,physical interaction,in vivo,two hybrid ComPPI,HPRD
DRD2 NCS1 12351722 14525934 25348397 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD
DTX2 NCS1 14525934 16189514 21516116 24234451 25348397 25416956 physical association two hybrid,physical interaction,two hybrid array,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid prey pooling approach,validated two hybrid,two hybrid ComPPI,HPRD,IntAct
NCS1 IL1RAPL1 12783849 14525934 25348397 27898060 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD,OmniPath
NCS1 PI4KB 11526106 12244129 14525934 14607934 25348397 27898060 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD,OmniPath
NCS1 DRD5 12351722 14525934 25348397 N/A two hybrid,two hybrid ComPPI,HPRD
NCS1 ELAVL1 25348397 N/A physical interaction ComPPI
NCS1 NAF1 25348397 N/A physical interaction ComPPI
NCS1 NUFIP1 25348397 N/A physical interaction ComPPI
NCS1 NMT2 25348397 N/A physical interaction ComPPI
NCS1 USP24 25348397 N/A physical interaction ComPPI
NCS1 NMT1 25348397 N/A physical interaction ComPPI
NCS1 ICAM1 25348397 N/A physical interaction ComPPI
NCS1 CNOT3 25348397 N/A physical interaction ComPPI
NCS1 SIGLEC9 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
NCS1 FZD7 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
TRAF2 NCS1 24234451 30561431 association virotrap IntAct
RBCK1 NCS1 24234451 30561431 association virotrap IntAct
SHARPIN NCS1 24234451 30561431 association virotrap IntAct
TANK NCS1 24234451 30561431 association virotrap IntAct
TNIP2 NCS1 24234451 30561431 association virotrap IntAct
NCS1 TRPC5 16469785 27898060 stimulant N/A OmniPath

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