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GENE：COPB2

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol COPB2
FullNmae COPI coat complex subunit beta 2
LocusType gene with protein product
Status Approved
HGNC_id HGNC:2232
EnsembleID ENSG00000184432
Uniprot P35606

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
COPB2 pyroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
COPB2 cuproptosis 36010978 Derived from the genome-wide CRISPR-Cas9 loss-of-function test reported in previous literature, 347 potential cuproptosis-related genes (FDR < 0.05) were identified, and for a detailed list of genes, see聽Supplementary Table S1. Cuproptosis-related genes
COPB2 cuproptosis 36550822 Next, 11 hub CAGs(cuproptosis-associated genes), including COPB2, MRPL39, PGK1, PRDX1, PCMT1, MPZL3, LACTB2, HSPH1, DIP2B, DLG3, and NFKBIA, were applied to construct a novel prognostic risk signature for BR. cuproptosis-associated gene

Go Annotation:

GeneSymbol Go id
COPB2 GO:0000139,GO:0005198,GO:0005515,GO:0005789,GO:0005829,GO:0006886,GO:0006888,GO:0006890,GO:0006890,GO:0006890,GO:0006891,GO:0006891,GO:0030126,GO:0030126,GO:0030133

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
AR COPB2 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 COPB2 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA2 COPB2 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 COPB2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS COPB2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A COPB2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF COPB2 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000070B1D COPB2 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00001CC4BD COPB2 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS00002C28B2 COPB2 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS000016E46F COPB2 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS00001C04A2 COPB2 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS0000122ED0 COPB2 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS00002F8148 COPB2 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS0000324096 COPB2 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS00003BD367 COPB2 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS00004C689A COPB2 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS00001FFA8C COPB2 23313552 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
COPB1 COPB2 25361965 interaction type N/A PTMCode2
COPB2 COPB1 25361965 interaction type N/A PTMCode2
COPB2 COPA 25361965 interaction type N/A PTMCode2
COPA COPB2 25361965 interaction type N/A PTMCode2
ARCN1 COPB2 25361965 interaction type N/A PTMCode2
COPB2 ARCN1 25361965 interaction type N/A PTMCode2
CDC6 COPB2 25361965 interaction type N/A PTMCode2
COPB2 CDC6 25361965 interaction type N/A PTMCode2
RGS2 COPB2 25361965 interaction type N/A PTMCode2
COPB2 RGS2 25361965 interaction type N/A PTMCode2
CDK2 COPB2 25361965 interaction type N/A PTMCode2
COPB2 CDK2 25361965 interaction type N/A PTMCode2
PRKCE COPB2 25361965 interaction type N/A PTMCode2
COPB2 PRKCE 25361965 interaction type N/A PTMCode2
ARF4 COPB2 25361965 interaction type N/A PTMCode2
COPB2 ARF4 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
SNW1 COPB2 20467437 24234451 25348397 association anti bait coimmunoprecipitation ComPPI,IntAct
CDC5L COPB2 20467437 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
CIAO1 COPB2 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
CEP19 COPB2 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
TUBB COPB2 25348397 N/A physical interaction ComPPI
WBP2 COPB2 25348397 N/A physical interaction ComPPI
MAGEA6 COPB2 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
RINT1 COPB2 24056303 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
CETN2 COPB2 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
JUN COPB2 24234451 25348397 25609649 association anti bait coimmunoprecipitation ComPPI,IntAct
PRKCE COPB2 14525934 25348397 9360998 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
CUL3 COPB2 25348397 N/A physical interaction ComPPI
NTRK1 COPB2 25348397 N/A physical interaction ComPPI
CANX COPB2 24234451 25348397 29568061 association pull down,proximity-dependent biotin identification ComPPI,IntAct
RGS4 COPB2 10982407 14525934 25348397 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD
COPB1 COPB2 25348397 N/A physical interaction ComPPI
COPA COPB2 10921873 14525934 14729954 22863883 22939629 25348397 26344197 27898060 8537409 8940050 9482852 9751720 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD,OmniPath
ILK COPB2 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
MYC COPB2 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
NELFCD COPB2 25348397 N/A physical interaction ComPPI
RGS2 COPB2 10982407 14525934 25348397 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,two hybrid ComPPI,HPRD
CFTR COPB2 25348397 N/A physical interaction ComPPI
COPB2 ARCN1 14525934 25348397 8940050 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
COPB2 SACM1L 14525934 14527956 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
COPB2 NDRG1 14525934 17220478 24234451 25348397 physical association anti bait coimmunoprecipitation,experimental interaction detection,physical interaction,in vivo ComPPI,HPRD,IntAct
COPB2 TSC22D1 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
COPB2 NFKB1 21988832 24234451 25348397 25609649 association,physical association two hybrid,physical interaction,tandem affinity purification ComPPI,IntAct
COPB2 COPE 25348397 N/A physical interaction ComPPI
COPB2 COPG1 25348397 N/A physical interaction ComPPI
COPB2 UBA5 20562859 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
COPB2 HDAC5 25348397 N/A physical interaction ComPPI
COPB2 SIRT7 25348397 N/A physical interaction ComPPI
COPB2 TMED10 24234451 25348397 9472029 association affinity chromatography technology,physical interaction ComPPI,IntAct
COPB2 COPG2 25348397 N/A physical interaction ComPPI
COPB2 LMAN1 25348397 N/A physical interaction ComPPI
COPB2 COPZ1 25348397 N/A physical interaction ComPPI
COPB2 FBXO6 25348397 N/A physical interaction ComPPI
COPB2 KLC4 25348397 N/A physical interaction ComPPI
COPB2 RUFY1 25348397 N/A physical interaction ComPPI
COPB2 TELO2 25348397 N/A physical interaction ComPPI
COPB2 TTI1 25348397 N/A physical interaction ComPPI
COPB2 NUDCD1 24234451 25036637 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
COPB2 HUWE1 25348397 N/A physical interaction ComPPI
COPB2 RNF2 25348397 N/A physical interaction ComPPI
COPB2 UNK 25348397 N/A physical interaction ComPPI
COPB2 TRIP10 25348397 N/A physical interaction ComPPI
COPB2 TUBB4B 25348397 N/A physical interaction ComPPI
COPB2 HERC2 24234451 25348397 29426014 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
COPB2 HERC2P3 25348397 N/A physical interaction ComPPI
COPB2 CNTRL 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
COPB2 TMEM237 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
COPB2 XPO1 25348397 N/A physical interaction ComPPI
COPB2 RNF126 25348397 N/A physical interaction ComPPI
COPB2 FAM210A 25348397 N/A physical interaction ComPPI
COPB2 MYO6 25348397 N/A physical interaction ComPPI
COPB2 ZNF746 25348397 N/A physical interaction ComPPI
COPB2 PPM1G 25348397 N/A physical interaction ComPPI
COPB2 ATP5F1D 25348397 N/A physical interaction ComPPI
COPB2 EDEM3 25348397 N/A physical interaction ComPPI
COPB2 MCPH1 25348397 N/A physical interaction ComPPI
COPB2 BRCA1 25348397 N/A physical interaction ComPPI
COPB2 NBAS 24056303 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
COPB2 ZW10 24056303 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
COPB2 UVRAG 24056303 24234451 25348397 association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
COPB2 KDM1A 25348397 N/A pull down,physical interaction ComPPI
COPB2 BRF2 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
COPB2 MCC 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
COPB2 TNFRSF10D 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
COPB2 TNIK 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
COPB2 GIPC1 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
COPB2 RTCA 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
COPB2 CDK4 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
COPB2 PRKAB1 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
COPB2 GSTK1 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
COPB2 ESR2 21182203 24234451 25348397 25604459 association affinity chromatography technology,tandem affinity purification ComPPI,IntAct
COPB2 TMED9 24234451 25348397 9472029 association affinity chromatography technology ComPPI,IntAct
COPB2 TGOLN2 24234451 25348397 29568061 association pull down,proximity-dependent biotin identification ComPPI,IntAct
COPB2 MFHAS1 24234451 25348397 29513927 N/A protein array ComPPI,IntAct
KCNJ10 COPB2 25348397 N/A physical interaction ComPPI
DDA1 COPB2 25348397 N/A physical interaction ComPPI

Visualization










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