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GENE：COQ2

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol COQ2
FullNmae coenzyme Q2, polyprenyltransferase
LocusType gene with protein product
Status Approved
HGNC_id HGNC:25223
EnsembleID ENSG00000173085
Uniprot Q96H96

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
COQ2 ferroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
COQ2 cuproptosis 36010978 Derived from the genome-wide CRISPR-Cas9 loss-of-function test reported in previous literature, 347 potential cuproptosis-related genes (FDR < 0.05) were identified, and for a detailed list of genes, see聽Supplementary Table S1. Cuproptosis-related genes

Go Annotation:

GeneSymbol Go id
COQ2 GO:0002083,GO:0002083,GO:0002083,GO:0004659,GO:0005743,GO:0005743,GO:0006071,GO:0006744,GO:0006744,GO:0006744,GO:0006744,GO:0006744,GO:0006744,GO:0008299,GO:0008412,GO:0047293

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
COQ2 hsa:27235 path:hsa00130 Ubiquinone and other terpenoid-quinone biosynthesis - Homo sapiens (human)
COQ2 hsa:27235 path:hsa01100 Metabolic pathways - Homo sapiens (human)
COQ2 hsa:27235 path:hsa01240 Biosynthesis of cofactors - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
SMARCA4 COQ2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA COQ2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF COQ2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 COQ2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 COQ2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 COQ2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ETS1 COQ2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 COQ2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS COQ2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
GATA2 COQ2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A COQ2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
PRDM14 COQ2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TAL1 COQ2 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
CHCHD3 COQ2 24234451 25348397 29128334 association cross-linking study ComPPI,IntAct
NUDT21 COQ2 24234451 25348397 29128334 association cross-linking study ComPPI,IntAct
CHCHD2 COQ2 24234451 25348397 27499296 association anti tag coimmunoprecipitation ComPPI,IntAct
LDHB COQ2 24234451 25348397 29128334 association cross-linking study ComPPI,IntAct
CASP14 COQ2 24234451 25348397 29128334 association cross-linking study ComPPI,IntAct
SET COQ2 24234451 25348397 29128334 association cross-linking study ComPPI,IntAct
SLC25A6 COQ2 24234451 25348397 27499296 29128334 association anti tag coimmunoprecipitation,cross-linking study ComPPI,IntAct
UQCRH COQ2 24234451 25348397 27499296 association anti tag coimmunoprecipitation ComPPI,IntAct
JUP COQ2 24234451 25348397 29128334 association cross-linking study ComPPI,IntAct
SCYL2 COQ2 24234451 25348397 29128334 association cross-linking study ComPPI,IntAct
YWHAZ COQ2 24234451 25348397 29128334 association cross-linking study ComPPI,IntAct
PPM1A COQ2 24234451 25348397 29128334 association cross-linking study ComPPI,IntAct
IDH2 COQ2 24234451 25348397 29128334 association cross-linking study ComPPI,IntAct
SSBP1 COQ2 24234451 25348397 29128334 association cross-linking study ComPPI,IntAct
TXN COQ2 24234451 25348397 29128334 association cross-linking study ComPPI,IntAct
C1QBP COQ2 24234451 25348397 27499296 association anti tag coimmunoprecipitation ComPPI,IntAct
TPM3 COQ2 24234451 25348397 29128334 association cross-linking study ComPPI,IntAct
PDHB COQ2 24234451 25348397 29128334 association cross-linking study ComPPI,IntAct
PDHA1 COQ2 24234451 25348397 29128334 association cross-linking study ComPPI,IntAct
EPRS1 COQ2 24234451 25348397 29128334 association cross-linking study ComPPI,IntAct
TRAP1 COQ2 24234451 25348397 29128334 association cross-linking study ComPPI,IntAct
VDAC2 COQ2 24234451 25348397 29128334 association cross-linking study ComPPI,IntAct
SERPINB12 COQ2 24234451 25348397 29128334 association cross-linking study ComPPI,IntAct
BCLAF1 COQ2 24234451 25348397 29128334 association cross-linking study ComPPI,IntAct
PPM1B COQ2 24234451 25348397 29128334 association cross-linking study ComPPI,IntAct
PIP5K1C COQ2 24234451 25348397 29128334 association cross-linking study ComPPI,IntAct
NOP56 COQ2 24234451 25348397 29128334 association cross-linking study ComPPI,IntAct
ILF2 COQ2 24234451 25348397 29128334 association cross-linking study ComPPI,IntAct
SAFB COQ2 24234451 25348397 29128334 association cross-linking study ComPPI,IntAct
RCC2 COQ2 24234451 25348397 29128334 association cross-linking study ComPPI,IntAct
ALYREF COQ2 24234451 25348397 29128334 association cross-linking study ComPPI,IntAct
RBMXL2 COQ2 24234451 25348397 29128334 association cross-linking study ComPPI,IntAct
H2AC4 COQ2 24234451 25348397 29128334 association cross-linking study ComPPI,IntAct
RNPS1 COQ2 24234451 25348397 29128334 association cross-linking study ComPPI,IntAct
THRAP3 COQ2 24234451 25348397 29128334 association cross-linking study ComPPI,IntAct
EIF4A3 COQ2 24234451 25348397 29128334 association cross-linking study ComPPI,IntAct
GFAP COQ2 24234451 25348397 29128334 association cross-linking study ComPPI,IntAct
ARF1 COQ2 24234451 25348397 29128334 association cross-linking study ComPPI,IntAct
DSG1 COQ2 24234451 25348397 29128334 association cross-linking study ComPPI,IntAct
DSP COQ2 24234451 25348397 29128334 association cross-linking study ComPPI,IntAct
ATP5F1C COQ2 24234451 25348397 29128334 association cross-linking study ComPPI,IntAct
MDH2 COQ2 24234451 25348397 29128334 association cross-linking study ComPPI,IntAct
SLC25A5 COQ2 24234451 25348397 29128334 association cross-linking study ComPPI,IntAct
CPSF6 COQ2 24234451 25348397 29128334 association cross-linking study ComPPI,IntAct
DKC1 COQ2 24234451 25348397 29128334 association cross-linking study ComPPI,IntAct
SLC25A3 COQ2 24234451 25348397 29128334 association cross-linking study ComPPI,IntAct
SLC25A4 COQ2 24234451 25348397 29128334 association cross-linking study ComPPI,IntAct
TKT COQ2 24234451 25348397 29128334 association cross-linking study ComPPI,IntAct
STOML2 COQ2 24234451 25348397 29128334 association cross-linking study ComPPI,IntAct
H1-0 COQ2 24234451 25348397 29128334 association cross-linking study ComPPI,IntAct
ATAD3A COQ2 24234451 25348397 29128334 association cross-linking study ComPPI,IntAct
DCD COQ2 24234451 25348397 29128334 association cross-linking study ComPPI,IntAct
HRNR COQ2 24234451 25348397 29128334 association cross-linking study ComPPI,IntAct
SFXN1 COQ2 24234451 25348397 29128334 association cross-linking study ComPPI,IntAct
RSL1D1 COQ2 24234451 25348397 29128334 association cross-linking study ComPPI,IntAct
H1-10 COQ2 24234451 25348397 29128334 association cross-linking study ComPPI,IntAct
LONP1 COQ2 24234451 25348397 29128334 association cross-linking study ComPPI,IntAct
H2AZ2 COQ2 24234451 25348397 29128334 association cross-linking study ComPPI,IntAct
RPL27 COQ2 24234451 25348397 29128334 association cross-linking study ComPPI,IntAct

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