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GENE：COQ7

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol COQ7
FullNmae coenzyme Q7, hydroxylase
LocusType gene with protein product
Status Approved
HGNC_id HGNC:2244
EnsembleID ENSG00000167186
Uniprot Q99807

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
COQ7 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
COQ7 cuproptosis 36010978 Derived from the genome-wide CRISPR-Cas9 loss-of-function test reported in previous literature, 347 potential cuproptosis-related genes (FDR < 0.05) were identified, and for a detailed list of genes, see聽Supplementary Table S1. Cuproptosis-related genes

Go Annotation:

GeneSymbol Go id
COQ7 GO:0005515,GO:0005634,GO:0005634,GO:0005694,GO:0005743,GO:0005743,GO:0006744,GO:0006744,GO:0006744,GO:0008340,GO:0008682,GO:0010468,GO:0016709,GO:0031314,GO:0046872,GO:0110142,GO:2000377

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
COQ7 hsa:10229 path:hsa00130 Ubiquinone and other terpenoid-quinone biosynthesis - Homo sapiens (human)
COQ7 hsa:10229 path:hsa01100 Metabolic pathways - Homo sapiens (human)
COQ7 hsa:10229 path:hsa01240 Biosynthesis of cofactors - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
ETS1 COQ7 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA1 COQ7 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA2 COQ7 18971253 19941826 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
HIF1A COQ7 19828020 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
SMARCA4 COQ7 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA COQ7 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF COQ7 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 COQ7 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 COQ7 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXP1 COQ7 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS COQ7 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A COQ7 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF COQ7 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TP53 COQ7 N/A trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00003003B4 COQ7 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000002569A COQ7 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00001A4ABF COQ7 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00005194EC COQ7 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00005D986D COQ7 19536157 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000508C13 COQ7 19536157 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000021D08 COQ7 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000184017 COQ7 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00004AAAFF COQ7 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00000AA464 COQ7 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000367985 COQ7 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00003D8730 COQ7 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS0000306C70 COQ7 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS00001E3523 COQ7 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS00000C48FA COQ7 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS00003B59DF COQ7 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS0000486E0B COQ7 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS000047A67D COQ7 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS000013ABA3 COQ7 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS00000753AD COQ7 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000034B6F5 COQ7 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000043C1C3 COQ7 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00001481F9 COQ7 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS0000221168 COQ7 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000075C4B1 COQ7 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000075BDAA COQ7 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00000EC1BE COQ7 25416803 27292025 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
CHCHD2 COQ7 24234451 25348397 27499296 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
CYCS COQ7 24234451 25348397 27499296 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
POLDIP2 COQ7 24234451 25348397 27499296 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
C1QBP COQ7 24234451 25348397 27499296 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
BIRC5 COQ7 25348397 N/A anti bait coimmunoprecipitation,physical interaction ComPPI
SHMT2 COQ7 24234451 25348397 27499296 association anti tag coimmunoprecipitation ComPPI,IntAct
ATP5F1C COQ7 24234451 25348397 27499296 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
SLC25A5 COQ7 24234451 25348397 27499296 association anti tag coimmunoprecipitation ComPPI,IntAct
ECH1 COQ7 24234451 25348397 27499296 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
COQ8A COQ7 25348397 N/A physical interaction ComPPI
IDE COQ7 25348397 N/A physical interaction ComPPI
COX6B1 COQ7 24234451 25348397 27499296 association anti tag coimmunoprecipitation ComPPI,IntAct
MRPL13 COQ7 24234451 25348397 27499296 association anti tag coimmunoprecipitation ComPPI,IntAct
GLRX5 COQ7 25348397 N/A physical interaction ComPPI

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