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GENE：COX18

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol COX18
FullNmae cytochrome c oxidase assembly factor COX18
LocusType gene with protein product
Status Approved
HGNC_id HGNC:26801
EnsembleID ENSG00000163626
Uniprot Q8N8Q8

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
COX18 cuproptosis 36010978 Derived from the genome-wide CRISPR-Cas9 loss-of-function test reported in previous literature, 347 potential cuproptosis-related genes (FDR < 0.05) were identified, and for a detailed list of genes, see聽Supplementary Table S1. Cuproptosis-related genes

Go Annotation:

GeneSymbol Go id
COX18 GO:0005515,GO:0005743,GO:0008535,GO:0032977,GO:0032977,GO:0032977,GO:0032979,GO:0032979,GO:0033617,GO:0033617,GO:0051204

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
COX18 hsa:285521 path:hsa04714 Thermogenesis - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
AR COX18 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
E2F4 COX18 17531812 18971253 trascriptional regulation,stimulation chromatin immunoprecipitation array,inferred by curator TFlink
ETS1 COX18 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA1 COX18 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA2 COX18 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
YBX1 COX18 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
FOXP3 COX18 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
SMARCA4 COX18 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA COX18 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000568FF8 COX18 23313552 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000075D814 COX18 23313552 23824327 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000075CC78 COX18 23313552 23824327 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS0000209F04 COX18 23313552 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000453664 COX18 23313552 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00000E7139 COX18 23313552 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00001012BC COX18 23313552 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000013ABA3 COX18 23313552 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000021202F COX18 23313552 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00000AD002 COX18 23706177 25416803 mrna cleavage,inhibition clip TarBase
URS000075C4B1 COX18 23706177 25416803 mrna cleavage,inhibition clip TarBase
URS00000C4DB5 COX18 23706177 25416803 mrna cleavage,inhibition clip TarBase
URS000007F792 COX18 23706177 25416803 mrna cleavage,inhibition clip TarBase
URS00004F2EB0 COX18 23706177 25416803 mrna cleavage,inhibition clip TarBase
URS00005D986D COX18 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS0000508C13 COX18 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS0000045DBD COX18 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS000075C1E1 COX18 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS00002A8BC6 COX18 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS000032AE90 COX18 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS00003E5ECC COX18 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS00000753AD COX18 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS000075A760 COX18 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS00002152A8 COX18 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS0000137EDE COX18 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS000019907A COX18 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS00002B0B46 COX18 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS0000076E54 COX18 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS000075D15B COX18 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS00001C770D COX18 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS00000C5969 COX18 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS00003D4175 COX18 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS0000411672 COX18 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00004F859B COX18 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000075A608 COX18 25416803 27292025 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
VNN2 COX18 25348397 N/A physical interaction ComPPI

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