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GENE：CSTF3

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol CSTF3
FullNmae cleavage stimulation factor subunit 3
LocusType gene with protein product
Status Approved
HGNC_id HGNC:2485
EnsembleID ENSG00000176102
Uniprot Q12996

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
CSTF3 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
CSTF3 autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
CSTF3 cuproptosis 36010978 Derived from the genome-wide CRISPR-Cas9 loss-of-function test reported in previous literature, 347 potential cuproptosis-related genes (FDR < 0.05) were identified, and for a detailed list of genes, see聽Supplementary Table S1. Cuproptosis-related genes

Go Annotation:

GeneSymbol Go id
CSTF3 GO:0003723,GO:0003729,GO:0005515,GO:0005634,GO:0005654,GO:0005654,GO:0005848,GO:0031123,GO:0180010

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
CSTF3 hsa:1479 path:hsa03015 mRNA surveillance pathway - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
E2F4 CSTF3 17531812 18971253 trascriptional regulation,stimulation chromatin immunoprecipitation array,inferred by curator TFlink
ETS1 CSTF3 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
YBX1 CSTF3 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
TFAP2C CSTF3 20629094 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 CSTF3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA CSTF3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF CSTF3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 CSTF3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
GATA2 CSTF3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TP53 CSTF3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MYC CSTF3 N/A trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00000451A1 CSTF3 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000028BB8 CSTF3 23622248 25416803 mrna cleavage,inhibition clash TarBase

Source Target Pmid Interactiontype Methods Database
CSTF1 CSTF3 25361965 interaction type N/A PTMCode2
CSTF3 CSTF1 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
SNW1 CSTF3 20467437 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
CDC73 CSTF3 19136632 24234451 25348397 association,physical association anti bait coimmunoprecipitation,cosedimentation through density gradient,physical interaction ComPPI,IntAct
CDC5L CSTF3 20467437 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
HSPA8 CSTF3 25348397 N/A physical interaction ComPPI
NPM1 CSTF3 21822216 24234451 25348397 association anti bait coimmunoprecipitation ComPPI,IntAct
TP53BP1 CSTF3 24234451 25348397 29656893 association proximity-dependent biotin identification ComPPI,IntAct
FIP1L1 CSTF3 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
RBBP6 CSTF3 25348397 N/A physical interaction ComPPI
CUL3 CSTF3 25348397 N/A physical interaction ComPPI
GAPDH CSTF3 25348397 N/A physical interaction ComPPI
DLD CSTF3 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
NTRK1 CSTF3 25348397 N/A physical interaction ComPPI
HNRNPL CSTF3 25348397 N/A physical interaction ComPPI
PABPC1 CSTF3 25348397 N/A physical interaction ComPPI
XPO1 CSTF3 25348397 N/A physical interaction ComPPI
PAPOLA CSTF3 25348397 N/A physical interaction ComPPI
MACROD1 CSTF3 25348397 N/A physical interaction ComPPI
CYP1A1 CSTF3 25348397 N/A physical interaction ComPPI
EGFR CSTF3 25348397 N/A physical interaction ComPPI
VHL CSTF3 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
GTF2E2 CSTF3 25348397 N/A physical interaction ComPPI
POLR2A CSTF3 25348397 N/A physical interaction ComPPI
WWOX CSTF3 25348397 N/A physical interaction ComPPI
CUL7 CSTF3 25348397 N/A physical interaction ComPPI
H3C1 CSTF3 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
CSTF2 CSTF3 10669729 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
CSTF3 CSTF1 10669729 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
CSTF3 HNRNPA1 25348397 N/A physical interaction ComPPI
CSTF3 HECW2 25348397 N/A physical interaction ComPPI
CSTF3 CCNL2 25348397 N/A physical interaction ComPPI
CSTF3 UNK 25348397 N/A physical interaction ComPPI
CSTF3 PABPC3 25348397 N/A physical interaction ComPPI
CSTF3 SYMPK 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
CSTF3 RNPS1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
CSTF3 CPSF3 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
CSTF3 SSU72 25348397 N/A physical interaction ComPPI
CSTF3 BMP1 25348397 N/A physical interaction ComPPI
CSTF3 C1QL4 25348397 N/A physical interaction ComPPI
CSTF3 TRIM25 25348397 N/A physical interaction ComPPI
CSTF3 CDK4 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
CSTF3 IKBKE 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
CSTF3 CEP170P1 24234451 25348397 26496610 association anti tag coimmunoprecipitation ComPPI,IntAct
CPSF1 CSTF3 25348397 N/A physical interaction ComPPI
CSTF2T CSTF3 25348397 N/A physical interaction ComPPI
CSTF3 DAPK3 24234451 30021884 physical association cross-linking study IntAct
CSTF3 DST 24234451 30021884 physical association cross-linking study IntAct
CSTF3 MYO6 24234451 30021884 physical association cross-linking study IntAct

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