GENE:CYP2D6
GeneInfo:
GeneAttribute | GeneDescription |
---|---|
GeneSymbol | CYP2D6 |
FullNmae | cytochrome P450 family 2 subfamily D member 6 |
LocusType | gene with protein product |
Status | Approved |
HGNC_id | HGNC:2625 |
EnsembleID | ENSG00000100197 |
Uniprot | P10635 |
Protein Structure:
Gene Description in Publicaton:
GeneSymbol | CellDeathType | PMID | Description | GeneType |
---|---|---|---|---|
CYP2D6 | cuproptosis | 38187219 | DLAT acetylates the k76 site of 6-phosphogluconate dehydrogenase, and CYP2D6 regulates protein reduction, which in turn regulates intracellular copper levels. | regulator |
CYP2D6 | cuproptosis | 36072790 | CYP2D6,聽DAPK2,聽BCL2,聽RANTES, and聽IL-8聽are all related to the redox characteristics of copper. | redox characteristics of copper |
Go Annotation:
GeneSymbol | Go id |
---|---|
CYP2D6 | GO:0004497,GO:0004497,GO:0005506,GO:0005737,GO:0005739,GO:0005783,GO:0005789,GO:0006805,GO:0006805,GO:0006805,GO:0006805,GO:0008202,GO:0008203,GO:0008210,GO:0009804,GO:0009820,GO:0009822,GO:0016098,GO:0016491,GO:0016712,GO:0016712,GO:0019369,GO:0020037,GO:0020037,GO:0033076,GO:0042178,GO:0042572,GO:0042572,GO:0042759,GO:0043231,GO:0046483,GO:0051100,GO:0062187,GO:0062188,GO:0062189,GO:0070989,GO:0090350 |
KEGG Annotation:
GeneSymbol | GeneID | Pathway | Pathway Name |
---|---|---|---|
CYP2D6 | hsa:1565 | path:hsa00980 | Metabolism of xenobiotics by cytochrome P450 - Homo sapiens (human) |
CYP2D6 | hsa:1565 | path:hsa00982 | Drug metabolism - cytochrome P450 - Homo sapiens (human) |
CYP2D6 | hsa:1565 | path:hsa01522 | Endocrine resistance - Homo sapiens (human) |
CYP2D6 | hsa:1565 | path:hsa04726 | Serotonergic synapse - Homo sapiens (human) |