Gene Information gene info

GENE:DDX20

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol DDX20
FullNmae DEAD-box helicase 20
LocusType gene with protein product
Status Approved
HGNC_id HGNC:2743
EnsembleID ENSG00000064703
Uniprot Q9UHI6

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
DDX20 cuproptosis 36010978 Derived from the genome-wide CRISPR-Cas9 loss-of-function test reported in previous literature, 347 potential cuproptosis-related genes (FDR < 0.05) were identified, and for a detailed list of genes, see聽Supplementary Table S1. Cuproptosis-related genes

Go Annotation:

GeneSymbol Go id
DDX20 GO:0000122,GO:0000244,GO:0000387,GO:0000387,GO:0000387,GO:0003677,GO:0003723,GO:0003724,GO:0005515,GO:0005524,GO:0005634,GO:0005654,GO:0005654,GO:0005737,GO:0005829,GO:0005829,GO:0005856,GO:0006396,GO:0008285,GO:0016020,GO:0016604,GO:0016887,GO:0019904,GO:0030674,GO:0032797,GO:0032797,GO:0032797,GO:0034719,GO:0042826,GO:0043065,GO:0043065,GO:0048477,GO:0050810,GO:0090571,GO:0097504,GO:0140297

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
E2F4 DDX20 17531812 18971253 trascriptional regulation,stimulation chromatin immunoprecipitation array,inferred by curator TFlink
SMARCA4 DDX20 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF DDX20 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 DDX20 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ETS1 DDX20 18971253 trascriptional regulation,stimulation inferred by curator TFlink
GATA2 DDX20 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR2 DDX20 N/A trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00004505E4 DDX20 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000005481D DDX20 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000324096 DDX20 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000023133F DDX20 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS000075D814 DDX20 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS000075CC78 DDX20 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00000939AF DDX20 20371350 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
SNRPD1 DDX20 25361965 interaction type N/A PTMCode2
DDX20 SNRPD1 25361965 interaction type N/A PTMCode2
SNRPD2 DDX20 25361965 interaction type N/A PTMCode2
DDX20 SNRPD2 25361965 interaction type N/A PTMCode2
DHX9 DDX20 25361965 interaction type N/A PTMCode2
DDX20 DHX9 25361965 interaction type N/A PTMCode2
GEMIN5 DDX20 25361965 interaction type N/A PTMCode2
DDX20 GEMIN5 25361965 interaction type N/A PTMCode2
ETV3 DDX20 25361965 interaction type N/A PTMCode2
DDX20 ETV3 25361965 interaction type N/A PTMCode2
DDX20 SMN1 25361965 interaction type N/A PTMCode2
SMN1 DDX20 25361965 interaction type N/A PTMCode2
GEMIN4 DDX20 25361965 interaction type N/A PTMCode2
DDX20 GEMIN4 25361965 interaction type N/A PTMCode2
SNRPD3 DDX20 25361965 interaction type N/A PTMCode2
DDX20 SNRPD3 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
MFAP1 DDX20 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
SNRPB DDX20 10601333 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
CIAO1 DDX20 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
CD2BP2 DDX20 25348397 N/A physical interaction ComPPI
CRYAB DDX20 25348397 N/A physical interaction ComPPI
SNRPF DDX20 10601333 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
LSM2 DDX20 25348397 N/A physical interaction ComPPI
UBL4A DDX20 25348397 N/A physical interaction ComPPI
TP53BP1 DDX20 24234451 25348397 29656893 association proximity-dependent biotin identification ComPPI,IntAct
SNRPG DDX20 10601333 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
SNRPD1 DDX20 10601333 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
KEAP1 DDX20 25348397 N/A physical interaction ComPPI
SMN1 DDX20 10601333 10942426 11714716 14525934 19928837 21072240 23752268 24234451 25348397 association anti bait coimmunoprecipitation,experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD,IntAct
CPSF7 DDX20 25348397 N/A physical interaction ComPPI
GEMIN6 DDX20 25348397 N/A physical interaction ComPPI
GEMIN7 DDX20 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PTPN9 DDX20 25348397 N/A physical interaction ComPPI
DDX20 ETV3 12007404 14525934 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
DDX20 NCOR2 25348397 N/A in vitro ComPPI
DDX20 NCOR1 12007404 14525934 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
DDX20 SNRPD2 10601333 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
DDX20 SNRPD3 10601333 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
DDX20 STXBP2 11748230 14525934 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
DDX20 GEMIN2 10601333 11714716 14525934 24234451 25348397 association anti bait coimmunoprecipitation,experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD,IntAct
DDX20 HDAC2 25348397 N/A in vivo ComPPI
DDX20 GEMIN5 11714716 14525934 24234451 25348397 26496610 association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD,IntAct
DDX20 AGO2 11914277 14525934 14970384 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
DDX20 HDAC5 12007404 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
DDX20 SIN3A 12007404 14525934 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
DDX20 STXBP3 12065586 14525934 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
DDX20 DHX9 11149922 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
DDX20 NR0B2 14525934 14963109 25348397 N/A two hybrid,two hybrid ComPPI,HPRD
DDX20 SNRPE 10601333 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
DDX20 PRRC2A 14525934 14667819 24234451 25348397 physical association two hybrid,physical interaction,two hybrid ComPPI,HPRD,IntAct
DDX20 GSK3B 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
DDX20 RNPS1 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
DDX20 PHB2 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
DDX20 PNKP 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
DDX20 POLR1E 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
DDX20 PPP4R2 25348397 N/A physical interaction ComPPI
DDX20 GEMIN4 10725331 11714716 14525934 23752268 24234451 25348397 association,physical association anti bait coimmunoprecipitation,coimmunoprecipitation,experimental interaction detection,filter binding,pull down,physical interaction,two hybrid array,two hybrid prey pooling approach ComPPI,HPRD,IntAct
DDX20 FBL 25348397 N/A physical interaction ComPPI
DDX20 GAR1 25348397 N/A physical interaction ComPPI
DDX20 SNUPN 25348397 N/A physical interaction ComPPI
DDX20 SNRPGP15 25348397 N/A physical interaction ComPPI
DDX20 SLX1A 19596235 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
DDX20 CLN3 20562859 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
DDX20 GIGYF2 25348397 N/A physical interaction ComPPI
DDX20 MYC 17314511 17353931 24234451 25348397 association,physical association anti bait coimmunoprecipitation,physical interaction,tandem affinity purification ComPPI,IntAct
DDX20 SIRT7 25348397 N/A physical interaction ComPPI
DDX20 TCF3 25348397 N/A physical interaction ComPPI
DDX20 COPS5 25348397 N/A physical interaction ComPPI
DDX20 COPA 25348397 N/A physical interaction ComPPI
DDX20 APP 25348397 N/A physical interaction ComPPI
DDX20 SRP9 25348397 N/A physical interaction ComPPI
DDX20 SRP54 25348397 N/A physical interaction ComPPI
DDX20 BARD1 25348397 N/A physical interaction ComPPI
DDX20 HDAC11 23752268 24234451 25348397 association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
DDX20 DICER1 23752268 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
DDX20 EGFR 25348397 N/A physical interaction ComPPI
DDX20 PARP16 25348397 N/A physical interaction ComPPI
DDX20 P2RY12 25348397 N/A physical interaction ComPPI
DDX20 DCLRE1C 25348397 N/A physical interaction ComPPI
DDX20 SCN2B 25348397 N/A physical interaction ComPPI
DDX20 ALDH3A2 25348397 N/A physical interaction ComPPI
DDX20 NSD2 25348397 N/A physical interaction ComPPI
DDX20 NTRK1 25348397 N/A physical interaction ComPPI
DDX20 NCBP1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
DDX20 STRAP 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
DDX20 CRY2 25348397 N/A physical interaction ComPPI
DDX20 NANOGP8 25348397 N/A physical interaction ComPPI
DDX20 NANOG 25348397 N/A physical interaction ComPPI
DDX20 POU5F1 25348397 N/A physical interaction ComPPI
DDX20 USP9X 25348397 N/A physical interaction ComPPI
DDX20 ITCH 25348397 N/A physical interaction ComPPI
DDX20 GEMIN8 25348397 N/A physical interaction ComPPI
DDX20 USO1 25348397 N/A physical interaction ComPPI
DDX20 SNRNP70 25348397 N/A physical interaction ComPPI
DDX20 LSM11 25348397 N/A physical interaction ComPPI
DDX20 PHAX 25348397 N/A physical interaction ComPPI
DDX20 GAPDHS 25348397 N/A physical interaction ComPPI
DDX20 SIGLECL1 25348397 N/A physical interaction ComPPI
DDX20 EAF1 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
DDX20 NAF1 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
DDX20 EIF2AK1 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
DDX20 AP3B1 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
DDX20 ATRX 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
DDX20 POLD1 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
DDX20 RBM14 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
DDX20 MCM3 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
DDX20 TRIM25 25348397 N/A physical interaction ComPPI
DDX20 NUFIP1 25348397 N/A physical interaction ComPPI
DDX20 WRAP53 21072240 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
DDX20 MED19 15175163 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
DDX20 MED29 15175163 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
DDX20 BRF2 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
DDX20 PTP4A3 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
DDX20 PRKAB1 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
DDX20 MAP1LC3A 20562859 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
DDX20 PARP2 21812934 24234451 25348397 adp ribosylation reaction protein array ComPPI,IntAct
DDX20 JUN 24234451 25348397 25609649 association anti bait coimmunoprecipitation ComPPI,IntAct
DDX20 PLEKHA7 24234451 25348397 28877994 association anti bait coimmunoprecipitation ComPPI,IntAct
COMTD1 DDX20 25348397 N/A physical interaction ComPPI
HSCB DDX20 24234451 25348397 28380382 association anti bait coimmunoprecipitation ComPPI,IntAct
NCBP3 DDX20 24234451 26382858 association pull down IntAct
NCBP2 DDX20 24234451 26382858 association pull down IntAct
PPM1G DDX20 17984321 27898060 N/A N/A OmniPath
DDX20 FOXL2 16153597 27898060 stimulant N/A OmniPath

Visualization