Gene Information gene info

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GENE：DHX15

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol DHX15
FullNmae DEAH-box helicase 15
LocusType gene with protein product
Status Approved
HGNC_id HGNC:2738
EnsembleID ENSG00000109606
Uniprot O43143

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
DHX15 cuproptosis 36010978 Derived from the genome-wide CRISPR-Cas9 loss-of-function test reported in previous literature, 347 potential cuproptosis-related genes (FDR < 0.05) were identified, and for a detailed list of genes, see聽Supplementary Table S1. Cuproptosis-related genes

Go Annotation:

GeneSymbol Go id
DHX15 GO:0000398,GO:0003723,GO:0003723,GO:0003723,GO:0003724,GO:0003725,GO:0004386,GO:0005515,GO:0005524,GO:0005622,GO:0005634,GO:0005654,GO:0005681,GO:0005689,GO:0005730,GO:0006397,GO:0008186,GO:0008380,GO:0009636,GO:0016607,GO:0016887,GO:0042742,GO:0043123,GO:0043279,GO:0051607,GO:0140374

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
DHX15 hsa:1665 path:hsa03040 Spliceosome - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
EED DHX15 23180781 24457600 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
AR DHX15 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 DHX15 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA1 DHX15 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA2 DHX15 18971253 19941826 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
YBX1 DHX15 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
FOXP3 DHX15 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
SMARCA4 DHX15 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA DHX15 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF DHX15 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 DHX15 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 DHX15 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 DHX15 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 DHX15 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXP1 DHX15 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS DHX15 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A DHX15 18971253 trascriptional regulation,stimulation inferred by curator TFlink
PRDM14 DHX15 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TAL1 DHX15 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00005651EE DHX15 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00000451A1 DHX15 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000170CF4 DHX15 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000000B1C9 DHX15 23622248 25416803 mrna cleavage,inhibition clash TarBase

Source Target Pmid Interactiontype Methods Database
SF3A3 DHX15 24234451 25348397 29021621 colocalization,association anti tag coimmunoprecipitation,physical interaction,fluorescence microscopy ComPPI,IntAct
PIN1 DHX15 25348397 N/A physical interaction ComPPI
HNRNPK DHX15 25348397 N/A physical interaction ComPPI
TXLNA DHX15 25348397 N/A physical interaction ComPPI
GPANK1 DHX15 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
SNW1 DHX15 20467437 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
CUL5 DHX15 25348397 N/A physical interaction ComPPI
RBM17 DHX15 22365833 24234451 25348397 25416956 29021621 association,physical association anti tag coimmunoprecipitation,two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
CDC5L DHX15 25348397 N/A physical interaction ComPPI
DHX15 YWHAB 14525934 15324660 24234451 25348397 physical association coimmunoprecipitation,experimental interaction detection,physical interaction,in vivo ComPPI,HPRD,IntAct
DHX15 YWHAG 14525934 15324660 24234451 25348397 physical association coimmunoprecipitation,experimental interaction detection,physical interaction,in vivo ComPPI,HPRD,IntAct
DHX15 SF3A2 17332742 24234451 24304693 25348397 association,physical association affinity chromatography technology,anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
DHX15 TAF10 25348397 N/A physical interaction ComPPI
DHX15 TOPORS 25348397 N/A physical interaction ComPPI
DHX15 TADA2A 25348397 N/A physical interaction ComPPI
DHX15 MYC 17314511 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
DHX15 HDAC5 25348397 N/A physical interaction ComPPI
DHX15 PINX1 21900206 24234451 24823796 25348397 27898060 physical association two hybrid,physical interaction ComPPI,IntAct,OmniPath
DHX15 HDGF 21907836 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
DHX15 ARRB2 17620599 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
DHX15 SIRT7 25348397 N/A physical interaction ComPPI
DHX15 HNRNPA1 25348397 N/A physical interaction ComPPI
DHX15 CUL3 25348397 N/A physical interaction ComPPI
DHX15 CUL4A 25348397 N/A physical interaction ComPPI
DHX15 CUL4B 25348397 N/A physical interaction ComPPI
DHX15 CUL2 25348397 N/A physical interaction ComPPI
DHX15 CDK2 25348397 N/A physical interaction ComPPI
DHX15 CUL1 25348397 N/A physical interaction ComPPI
DHX15 COPS5 25348397 N/A physical interaction ComPPI
DHX15 CAND1 25348397 N/A physical interaction ComPPI
DHX15 GRK5 25348397 N/A physical interaction ComPPI
DHX15 SF3B6 24234451 25348397 29021621 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
DHX15 SNRPD2 25348397 N/A physical interaction ComPPI
DHX15 SF3A1 24234451 24304693 25348397 29021621 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
DHX15 SRSF1 25348397 N/A physical interaction ComPPI
DHX15 DDX5 25348397 N/A physical interaction ComPPI
DHX15 PABPC1 25348397 N/A physical interaction ComPPI
DHX15 SRSF5 25348397 N/A physical interaction ComPPI
DHX15 HNRNPF 25348397 N/A physical interaction ComPPI
DHX15 SYNCRIP 25348397 N/A physical interaction ComPPI
DHX15 SRSF3 25348397 N/A physical interaction ComPPI
DHX15 ACIN1 25348397 N/A physical interaction ComPPI
DHX15 SRSF7 25348397 N/A physical interaction ComPPI
DHX15 SRRM2 25348397 N/A physical interaction ComPPI
DHX15 DEK 25348397 N/A physical interaction ComPPI
DHX15 RBMX 25348397 N/A physical interaction ComPPI
DHX15 NOP58 25348397 N/A physical interaction ComPPI
DHX15 RPL31 25348397 N/A physical interaction ComPPI
DHX15 NOP56 25348397 N/A physical interaction ComPPI
DHX15 SUPT16H 25348397 N/A physical interaction ComPPI
DHX15 FBL 25348397 N/A physical interaction ComPPI
DHX15 VTN 25348397 N/A physical interaction ComPPI
DHX15 ECSIT 25348397 N/A physical interaction ComPPI
DHX15 GTF3C1 25348397 N/A physical interaction ComPPI
DHX15 NDUFAF4 25348397 N/A physical interaction ComPPI
DHX15 PFN2 25348397 N/A physical interaction ComPPI
DHX15 TMEM126B 25348397 N/A physical interaction ComPPI
DHX15 S100A9 25348397 N/A physical interaction ComPPI
DHX15 SENP3 25348397 N/A physical interaction ComPPI
DHX15 EIF2D 25348397 N/A physical interaction ComPPI
DHX15 MMGT1 25348397 N/A physical interaction ComPPI
DHX15 RPL36 25348397 N/A physical interaction ComPPI
DHX15 SLC30A9 25348397 N/A physical interaction ComPPI
DHX15 PCDHA2 25348397 N/A physical interaction ComPPI
DHX15 RANBP2 25348397 N/A physical interaction ComPPI
DHX15 SRSF10 25348397 N/A physical interaction ComPPI
DHX15 LBR 25348397 N/A physical interaction ComPPI
DHX15 EBNA1BP2 25348397 N/A physical interaction ComPPI
DHX15 PEX3 25348397 N/A physical interaction ComPPI
DHX15 NXF1 25348397 N/A physical interaction ComPPI
DHX15 FUT8 25348397 N/A physical interaction ComPPI
DHX15 IWS1 25348397 N/A physical interaction ComPPI
DHX15 RPL22 25348397 N/A physical interaction ComPPI
DHX15 ESR1 21182205 24234451 25348397 association affinity chromatography technology,cosedimentation through density gradient,physical interaction ComPPI,IntAct
DHX15 NOTCH1 23022380 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
DHX15 EIF4A3 23084401 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
DHX15 MAGOH 23084401 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
DHX15 UBC 25348397 N/A physical interaction ComPPI
DHX15 POLR2C 18562274 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
DHX15 FN1 19738201 24234451 25348397 association cross-linking study,physical interaction ComPPI,IntAct
DHX15 VCAM1 19738201 22623428 24234451 25348397 association cross-linking study,physical interaction ComPPI,IntAct
DHX15 RBM10 22365833 24234451 25348397 29021621 association,physical association anti tag coimmunoprecipitation,two hybrid,physical interaction ComPPI,IntAct
DHX15 RBM5 22365833 22569250 24234451 24304693 25348397 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,two hybrid,pull down,physical interaction ComPPI,IntAct
DHX15 SUGP1 22365833 24234451 25348397 physical association anti tag coimmunoprecipitation,two hybrid,physical interaction ComPPI,IntAct
DHX15 DDX42 22365833 24234451 25348397 29021621 association,physical association anti tag coimmunoprecipitation,two hybrid,physical interaction ComPPI,IntAct
DHX15 TRA2A 22365833 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
DHX15 NKAP 22365833 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
DHX15 ITGA4 25348397 N/A physical interaction ComPPI
DHX15 CD81 25348397 N/A physical interaction ComPPI
DHX15 IGSF8 25348397 N/A physical interaction ComPPI
DHX15 NPM1 25348397 N/A physical interaction ComPPI
DHX15 SRPK2 23602568 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
DHX15 SRPK3 23602568 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
DHX15 FBXO6 25348397 N/A physical interaction ComPPI
DHX15 WBP4 16055720 24234451 25348397 28838205 physical association two hybrid,pull down,physical interaction,two hybrid array ComPPI,IntAct
DHX15 APBB1 25348397 N/A physical interaction ComPPI
DHX15 AHCY 25348397 N/A physical interaction ComPPI
DHX15 FH 25348397 N/A physical interaction ComPPI
DHX15 MSN 25348397 N/A physical interaction ComPPI
DHX15 NSFL1C 25348397 N/A physical interaction ComPPI
DHX15 PCNA 25348397 N/A physical interaction ComPPI
DHX15 PPP1CB 25348397 N/A physical interaction ComPPI
DHX15 MCTS1 25348397 N/A physical interaction ComPPI
DHX15 PAPSS1 25348397 N/A physical interaction ComPPI
DHX15 TMOD3 25348397 N/A physical interaction ComPPI
DHX15 RPA1 25348397 N/A physical interaction ComPPI
DHX15 RPA2 25348397 N/A physical interaction ComPPI
DHX15 RPA3 25348397 N/A physical interaction ComPPI
DHX15 WWOX 25348397 N/A physical interaction ComPPI
DHX15 NUDCD1 24234451 24304693 25036637 25348397 29021621 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
DHX15 STAU1 25348397 N/A physical interaction ComPPI
DHX15 CEP250 25348397 N/A physical interaction ComPPI
DHX15 CEP57 25348397 N/A physical interaction ComPPI
DHX15 FUS 25348397 N/A physical interaction ComPPI
DHX15 ZGPAT 19644445 24234451 25348397 25416956 association,physical association anti tag coimmunoprecipitation,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
DHX15 ENO1 25348397 N/A physical interaction ComPPI
DHX15 MOV10 25348397 N/A physical interaction ComPPI
DHX15 CUL7 25348397 N/A physical interaction ComPPI
DHX15 OBSL1 25348397 N/A physical interaction ComPPI
DHX15 EED 25348397 N/A physical interaction ComPPI
DHX15 EPB41L3 24234451 24366813 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
DHX15 UNK 25348397 N/A physical interaction ComPPI
DHX15 NTRK1 25348397 N/A physical interaction ComPPI
DHX15 ATXN2 25348397 N/A physical interaction ComPPI
DHX15 DDX17 25348397 N/A physical interaction ComPPI
DHX15 DDX43 25348397 N/A physical interaction ComPPI
DHX15 DDX18 25348397 N/A physical interaction ComPPI
DHX15 DHX37 25348397 N/A physical interaction ComPPI
DHX15 GGA1 25348397 N/A physical interaction ComPPI
DHX15 HNRNPL 25348397 N/A physical interaction ComPPI
DHX15 ILK 25348397 N/A physical interaction ComPPI
DHX15 KHDRBS1 25348397 N/A physical interaction ComPPI
DHX15 PUM3 25348397 N/A physical interaction ComPPI
DHX15 NDRG1 25348397 N/A physical interaction ComPPI
DHX15 PUS7 25348397 N/A physical interaction ComPPI
DHX15 SRRM1 25348397 N/A physical interaction ComPPI
DHX15 UFD1 25348397 N/A physical interaction ComPPI
DHX15 XAB2 25348397 N/A physical interaction ComPPI
DHX15 DKC1 25348397 N/A physical interaction ComPPI
DHX15 DNAJC9 25348397 N/A physical interaction ComPPI
DHX15 HNRNPR 25348397 N/A physical interaction ComPPI
DHX15 KIAA1143 25348397 N/A physical interaction ComPPI
DHX15 MSH2 25348397 N/A physical interaction ComPPI
DHX15 NEMF 25348397 N/A physical interaction ComPPI
DHX15 NOC2L 25348397 N/A physical interaction ComPPI
DHX15 NOL6 25348397 N/A physical interaction ComPPI
DHX15 NOLC1 25348397 N/A physical interaction ComPPI
DHX15 PABPC4 25348397 N/A physical interaction ComPPI
DHX15 PES1 25348397 N/A physical interaction ComPPI
DHX15 PRPF19 24234451 24304693 25348397 colocalization cosedimentation through density gradient,physical interaction ComPPI,IntAct
DHX15 PRPF4 25348397 N/A physical interaction ComPPI
DHX15 PRPF8 24234451 24304693 25348397 colocalization cosedimentation through density gradient,physical interaction ComPPI,IntAct
DHX15 RBM15 25348397 N/A physical interaction ComPPI
DHX15 RBM15B 25348397 N/A physical interaction ComPPI
DHX15 RPF2 25348397 N/A physical interaction ComPPI
DHX15 RPL12 25348397 N/A physical interaction ComPPI
DHX15 RSU1 25348397 N/A physical interaction ComPPI
DHX15 SEC31A 25348397 N/A physical interaction ComPPI
DHX15 SF3B1 24234451 24304693 25348397 29021621 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
DHX15 SF3B3 24234451 24304693 25348397 29021621 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
DHX15 MTREX 25348397 N/A physical interaction ComPPI
DHX15 SNRNP200 25348397 N/A physical interaction ComPPI
DHX15 SNRPA1 24234451 25348397 29021621 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
DHX15 SRSF11 25348397 N/A physical interaction ComPPI
DHX15 TDRD3 25348397 N/A physical interaction ComPPI
DHX15 TRMT112 25348397 N/A physical interaction ComPPI
DHX15 TTC27 25348397 N/A physical interaction ComPPI
DHX15 USP3 25348397 N/A physical interaction ComPPI
DHX15 WDR36 25348397 N/A physical interaction ComPPI
DHX15 ZYX 25348397 N/A physical interaction ComPPI
DHX15 SFN 25348397 N/A physical interaction ComPPI
DHX15 KIFAP3 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
DHX15 CRY2 25348397 N/A physical interaction ComPPI
DHX15 ALKBH3 25348397 N/A physical interaction ComPPI
DHX15 MCM5 25348397 N/A physical interaction ComPPI
DHX15 MCM2 25348397 N/A physical interaction ComPPI
DHX15 NF2 25348397 N/A physical interaction ComPPI
DHX15 USP37 25348397 N/A physical interaction ComPPI
DHX15 U2AF2 25348397 N/A physical interaction ComPPI
DHX15 ZNF746 25348397 N/A physical interaction ComPPI
DHX15 KNOP1 25348397 N/A physical interaction ComPPI
DHX15 NCL 25348397 N/A physical interaction ComPPI
DHX15 CYLD 25348397 N/A physical interaction ComPPI
DHX15 CD2BP2 25348397 N/A physical interaction ComPPI
DHX15 INO80B 25348397 N/A physical interaction ComPPI
DHX15 UBE2A 25348397 N/A physical interaction ComPPI
DHX15 BRCA1 25348397 N/A physical interaction ComPPI
DHX15 LMNA 25348397 N/A physical interaction ComPPI
DHX15 RNF168 25348397 N/A physical interaction ComPPI
DHX15 MTF1 25348397 N/A physical interaction ComPPI
DHX15 KEAP1 25348397 N/A physical interaction ComPPI
DHX15 AGO1 17932509 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
DHX15 AGO2 17932509 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
DHX15 MAP1LC3A 20562859 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
DHX15 GABARAPL2 20562859 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
DHX15 GABARAPL1 20562859 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
DHX15 GABARAP 20562859 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
DHX15 RNF169 21252943 24234451 25348397 association pull down ComPPI,IntAct
DHX15 DYSF 23414517 24234451 25348397 physical association two hybrid fragment pooling approach ComPPI,IntAct
DHX15 ANXA1 23754495 24234451 25348397 association anti bait coimmunoprecipitation ComPPI,IntAct
DHX15 PAXBP1 24234451 24304693 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
DHX15 TFIP11 24234451 24304693 25348397 29021621 colocalization,association anti tag coimmunoprecipitation,cosedimentation through density gradient ComPPI,IntAct
DHX15 CHERP 24234451 24304693 25348397 29021621 association anti tag coimmunoprecipitation ComPPI,IntAct
DHX15 SF3B4 24234451 24304693 25348397 29021621 association anti tag coimmunoprecipitation ComPPI,IntAct
DHX15 SMAP 24234451 24304693 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
DHX15 GCFC2 24234451 24304693 25348397 29021621 association anti tag coimmunoprecipitation ComPPI,IntAct
DHX15 SF3B2 24234451 24304693 25348397 29021621 association anti tag coimmunoprecipitation ComPPI,IntAct
DHX15 CMTR1 24234451 24304693 25348397 29021621 association anti tag coimmunoprecipitation ComPPI,IntAct
DHX15 AQR 24234451 24304693 25348397 colocalization cosedimentation through density gradient ComPPI,IntAct
DHX15 RALGAPB 24234451 24814574 25348397 association tandem affinity purification ComPPI,IntAct
DHX15 SF1 24234451 25348397 26420826 association anti bait coimmunoprecipitation ComPPI,IntAct
DHX15 JUN 24234451 25348397 25609649 association anti bait coimmunoprecipitation ComPPI,IntAct
DHX15 DDX41 24234451 25348397 25920683 association anti tag coimmunoprecipitation ComPPI,IntAct
DHX15 NKRF 24234451 25348397 29021621 association,physical association anti tag coimmunoprecipitation,two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
DHX15 AGGF1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
DHX15 KRT75 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
DHX15 REXO1L1P 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
DHX15 PLEKHA7 24234451 25348397 28877994 association anti bait coimmunoprecipitation ComPPI,IntAct
DHX15 RRP1B 20926688 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
PRPF40A DHX15 25348397 N/A physical interaction ComPPI
DHX15 MRPS18B 24234451 29021621 association anti tag coimmunoprecipitation IntAct
DHX15 SNRPB2 24234451 29021621 association anti tag coimmunoprecipitation IntAct
DHX15 LOXL4 24234451 29021621 association anti tag coimmunoprecipitation IntAct
DHX15 EIF3I 24234451 29021621 association anti tag coimmunoprecipitation IntAct
DHX15 LOXL2 24234451 29021621 association anti tag coimmunoprecipitation IntAct
DHX15 PPP1R3B 24234451 29021621 association anti tag coimmunoprecipitation IntAct
DHX15 SLC25A3 24234451 29021621 association anti tag coimmunoprecipitation IntAct
DHX15 SF3B5 24234451 29021621 association anti tag coimmunoprecipitation IntAct
DICER1 DHX15 21858095 24234451 association anti tag coimmunoprecipitation IntAct
H2BC21 DHX15 24234451 30021884 physical association cross-linking study IntAct

Visualization










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