GENE：DIP2B
GeneInfo:
| GeneAttribute | GeneDescription |
|---|---|
| GeneSymbol | DIP2B |
| FullNmae | disco interacting protein 2 homolog B |
| LocusType | gene with protein product |
| Status | Approved |
| HGNC_id | HGNC:29284 |
| EnsembleID | ENSG00000066084 |
| Uniprot | Q9P265 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol | CellDeathType | PMID | Description | GeneType |
|---|---|---|---|---|
| DIP2B | cuproptosis | 36550822 | Next, 11 hub CAGs(cuproptosis-associated genes), including COPB2, MRPL39, PGK1, PRDX1, PCMT1, MPZL3, LACTB2, HSPH1, DIP2B, DLG3, and NFKBIA, were applied to construct a novel prognostic risk signature for BR. | cuproptosis-associated gene |
Go Annotation:
| GeneSymbol | Go id |
|---|---|
| DIP2B | GO:0003674,GO:0005634,GO:0005737,GO:0007399,GO:0008150,GO:0016020,GO:0030424,GO:0030425,GO:0030517,GO:0043014,GO:0043204,GO:0070062,GO:2000758 |
Protein-Protein Interaction(String):
Gene-Drug Network:
Signalink 3.0 modificators
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| AR | DIP2B | 20610535 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| E2F4 | DIP2B | 17531812 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| ETS1 | DIP2B | 18971253 20019798 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| GATA2 | DIP2B | 18971253 19941826 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| YBX1 | DIP2B | 19151767 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| FOXP3 | DIP2B | 20554955 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| PRDM14 | DIP2B | 18971253 20953172 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| SMARCA4 | DIP2B | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CEBPA | DIP2B | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CTCF | DIP2B | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| E2F1 | DIP2B | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOXA1 | DIP2B | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOXP1 | DIP2B | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOS | DIP2B | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| HNF4A | DIP2B | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| MITF | DIP2B | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| TAL1 | DIP2B | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| RAD21 | DIP2B | 25348397 | N/A | physical interaction | ComPPI |
| NTRK1 | DIP2B | 25348397 | N/A | physical interaction | ComPPI |
| MYC | DIP2B | 21150319 24234451 25348397 | association | tandem affinity purification | ComPPI,IntAct |
| HNRNPL | DIP2B | 25348397 | N/A | physical interaction | ComPPI |
| SQSTM1 | DIP2B | 20562859 24234451 25348397 | physical association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| EFNB2 | DIP2B | 25348397 | N/A | physical interaction | ComPPI |
| SELE | DIP2B | 25348397 | N/A | physical interaction | ComPPI |
| TRIM25 | DIP2B | 25348397 | N/A | physical interaction | ComPPI |
| ELAVL1 | DIP2B | 25348397 | N/A | physical interaction | ComPPI |
| ARFGAP1 | DIP2B | 25348397 | N/A | physical interaction | ComPPI |
| EZR | DIP2B | 24234451 25348397 29568061 | association | proximity-dependent biotin identification | ComPPI,IntAct |
| HAVCR2 | DIP2B | 25348397 | N/A | physical interaction | ComPPI |