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GENE：DNTTIP2

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol DNTTIP2
FullNmae deoxynucleotidyltransferase terminal interacting protein 2
LocusType gene with protein product
Status Approved
HGNC_id HGNC:24013
EnsembleID ENSG00000067334
Uniprot Q5QJE6

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
DNTTIP2 cuproptosis 36010978 Derived from the genome-wide CRISPR-Cas9 loss-of-function test reported in previous literature, 347 potential cuproptosis-related genes (FDR < 0.05) were identified, and for a detailed list of genes, see聽Supplementary Table S1. Cuproptosis-related genes

Go Annotation:

GeneSymbol Go id
DNTTIP2 GO:0003723,GO:0005515,GO:0005654,GO:0005694,GO:0005730,GO:0005730,GO:0006396,GO:0032040,GO:0042274

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
AR DNTTIP2 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 DNTTIP2 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
CEBPA DNTTIP2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF DNTTIP2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 DNTTIP2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 DNTTIP2 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00005ACA7C DNTTIP2 20371350 21572407 23446348 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS00004F4657 DNTTIP2 20371350 21572407 23446348 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS00003E6EFA DNTTIP2 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS0000308E4D DNTTIP2 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000052EA98 DNTTIP2 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000025EABA DNTTIP2 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00000DDD35 DNTTIP2 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS0000298BA3 DNTTIP2 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00002B3783 DNTTIP2 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS0000042E1F DNTTIP2 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00002075FA DNTTIP2 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00000600E6 DNTTIP2 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000039E1E1 DNTTIP2 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000006F90B DNTTIP2 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00001919B0 DNTTIP2 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS000002569A DNTTIP2 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS00001A4ABF DNTTIP2 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS00005D986D DNTTIP2 22012620 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000508C13 DNTTIP2 22012620 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000039D790 DNTTIP2 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS0000085F64 DNTTIP2 21572407 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000076B539 DNTTIP2 21572407 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00000D2680 DNTTIP2 21572407 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00004283FE DNTTIP2 21572407 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000065FDF DNTTIP2 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000105D19 DNTTIP2 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00005606AA DNTTIP2 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000045DBD DNTTIP2 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000017EA6A DNTTIP2 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000000EF0B DNTTIP2 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000006BE7D DNTTIP2 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00004DA9DB DNTTIP2 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000032835F DNTTIP2 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS0000008A99 DNTTIP2 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00001C770D DNTTIP2 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS0000345DEB DNTTIP2 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS0000527B00 DNTTIP2 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00000C85B2 DNTTIP2 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00002152A8 DNTTIP2 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000019907A DNTTIP2 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS0000137EDE DNTTIP2 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000075A760 DNTTIP2 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000007F792 DNTTIP2 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000075AB0E DNTTIP2 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00000AD002 DNTTIP2 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS0000122F23 DNTTIP2 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000075C4B1 DNTTIP2 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00002A8BC6 DNTTIP2 25416803 27292025 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
ESR1 DNTTIP2 25361965 interaction type N/A PTMCode2
DNTTIP2 ESR1 25361965 interaction type N/A PTMCode2
DNTTIP2 PCNA 25361965 interaction type N/A PTMCode2
PCNA DNTTIP2 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
PCNA DNTTIP2 12786946 14525934 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
NIFK DNTTIP2 25348397 N/A physical interaction ComPPI
H4C1 DNTTIP2 25348397 N/A physical interaction ComPPI
PICK1 DNTTIP2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
FGF3 DNTTIP2 25348397 N/A physical interaction ComPPI
SPP1 DNTTIP2 25348397 N/A physical interaction ComPPI
RBM4 DNTTIP2 25348397 N/A physical interaction ComPPI
DNTT DNTTIP2 12786946 14525934 25348397 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,two hybrid ComPPI,HPRD
DNTTIP2 PPARG 14525934 1504714 25348397 27898060 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD,OmniPath
DNTTIP2 ESR2 14525934 15047147 25348397 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
DNTTIP2 ESR1 14525934 15047147 25348397 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD
DNTTIP2 RXRA 14525934 15047147 25348397 N/A experimental interaction detection,physical interaction ComPPI,HPRD
DNTTIP2 H2AW 25348397 N/A physical interaction ComPPI
DNTTIP2 H2BC1 25348397 N/A physical interaction ComPPI
DNTTIP2 H3C15 25348397 N/A physical interaction ComPPI
DNTTIP2 SIRT7 25348397 N/A physical interaction ComPPI
DNTTIP2 KAT5 25348397 N/A physical interaction ComPPI
DNTTIP2 HDAC11 23752268 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
DNTTIP2 OBSL1 25348397 N/A physical interaction ComPPI
DNTTIP2 HNRNPA1 25348397 N/A physical interaction ComPPI
DNTTIP2 IFI16 25348397 N/A physical interaction ComPPI
DNTTIP2 PHF8 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
DNTTIP2 DGCR8 25348397 N/A physical interaction ComPPI
DNTTIP2 ZNF2 25348397 N/A physical interaction ComPPI
DNTTIP2 FOXA1 25348397 N/A physical interaction ComPPI
DNTTIP2 TRIM25 25348397 N/A physical interaction ComPPI
DNTTIP2 NELL1 21723284 24234451 25348397 physical association phage display ComPPI,IntAct
DNTTIP2 TULP3 23414517 24234451 25348397 physical association two hybrid fragment pooling approach ComPPI,IntAct
DNTTIP2 RNF8 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
DNTTIP2 CAVIN1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
DNTTIP2 CEP70 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
DNTTIP2 RRP1B 20926688 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
DNTTIP2 FBL 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
MKI67 DNTTIP2 24234451 26949251 association anti tag coimmunoprecipitation IntAct
DNTTIP2 RBM6 24234451 30021884 physical association cross-linking study IntAct
DNTTIP2 RPF2 24234451 30021884 physical association cross-linking study IntAct
DNTTIP2 IFIT2 24234451 30021884 physical association cross-linking study IntAct
DNTTIP2 FAM50A 24234451 30021884 physical association cross-linking study IntAct
ATM DNTTIP2 20164059 27898060 N/A N/A OmniPath

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