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GENE：DTYMK

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol DTYMK
FullNmae deoxythymidylate kinase
LocusType gene with protein product
Status Approved
HGNC_id HGNC:3061
EnsembleID ENSG00000168393
Uniprot P23919

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
DTYMK mitotic_cd 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
DTYMK autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
DTYMK cuproptosis 36010978 Derived from the genome-wide CRISPR-Cas9 loss-of-function test reported in previous literature, 347 potential cuproptosis-related genes (FDR < 0.05) were identified, and for a detailed list of genes, see聽Supplementary Table S1. Cuproptosis-related genes

Go Annotation:

GeneSymbol Go id
DTYMK GO:0004550,GO:0004798,GO:0004798,GO:0005524,GO:0005634,GO:0005737,GO:0005739,GO:0005759,GO:0005829,GO:0006227,GO:0006233,GO:0006233,GO:0006235,GO:0006235,GO:0016310,GO:0043627,GO:0045445,GO:0046105,GO:0046105,GO:0046686,GO:0046940,GO:0071363

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
DTYMK hsa:1841 path:hsa00240 Pyrimidine metabolism - Homo sapiens (human)
DTYMK hsa:1841 path:hsa01100 Metabolic pathways - Homo sapiens (human)
DTYMK hsa:1841 path:hsa01232 Nucleotide metabolism - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
AR DTYMK 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 DTYMK 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA2 DTYMK 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
MYC DTYMK 18414489 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
CEBPA DTYMK 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF DTYMK 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 DTYMK 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS DTYMK 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A DTYMK 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF DTYMK 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00000EED18 DTYMK 21566225 25416803 mrna cleavage,inhibition experimental interaction detection TarBase
URS0000345DEB DTYMK 23622248 25416803 mrna cleavage,inhibition clash TarBase

Source Target Pmid Interactiontype Methods Database
DTYMK FEN1 25361965 interaction type N/A PTMCode2
FEN1 DTYMK 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
CDC5L DTYMK 20467437 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
DLD DTYMK 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
MAPK6 DTYMK 24234451 25348397 26972000 association anti tag coimmunoprecipitation ComPPI,IntAct
ATP6AP2 DTYMK 25348397 N/A physical interaction ComPPI
CDK9 DTYMK 25348397 N/A physical interaction ComPPI
PCMT1 DTYMK 25348397 N/A physical interaction ComPPI
POU5F1 DTYMK 25348397 N/A physical interaction ComPPI
MOV10 DTYMK 25348397 N/A physical interaction ComPPI
MEPCE DTYMK 25348397 N/A physical interaction ComPPI
DTYMK HSD17B7 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct

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