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GENE：DYNLRB1

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol DYNLRB1
FullNmae dynein light chain roadblock-type 1
LocusType gene with protein product
Status Approved
HGNC_id HGNC:15468
EnsembleID ENSG00000125971
Uniprot Q9NP97

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
DYNLRB1 cuproptosis 36010978 Derived from the genome-wide CRISPR-Cas9 loss-of-function test reported in previous literature, 347 potential cuproptosis-related genes (FDR < 0.05) were identified, and for a detailed list of genes, see聽Supplementary Table S1. Cuproptosis-related genes

Go Annotation:

GeneSymbol Go id
DYNLRB1 GO:0003777,GO:0005515,GO:0005737,GO:0005737,GO:0005813,GO:0005813,GO:0005868,GO:0005868,GO:0005868,GO:0005874,GO:0005929,GO:0007018,GO:0007018,GO:0007632,GO:0016020,GO:0030286,GO:0045505,GO:0097542

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
DYNLRB1 hsa:83658 path:hsa04814 Motor proteins - Homo sapiens (human)
DYNLRB1 hsa:83658 path:hsa05132 Salmonella infection - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
AR DYNLRB1 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 DYNLRB1 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA2 DYNLRB1 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
YBX1 DYNLRB1 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
TFAP2C DYNLRB1 20629094 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 DYNLRB1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA DYNLRB1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF DYNLRB1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 DYNLRB1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS DYNLRB1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 DYNLRB1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A DYNLRB1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF DYNLRB1 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
PRKACA DYNLRB1 22135298 phosphorylation N/A PhosphoSite
DYNC1H1 DYNLRB1 25361965 interaction type N/A PTMCode2
DYNLRB1 DYNC1H1 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
MAPRE1 DYNLRB1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
DYNLL1 DYNLRB1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
BCL2L11 DYNLRB1 10198631 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
DYNC2I2 DYNLRB1 24234451 25348397 27173435 association,physical association physical interaction,tandem affinity purification,inference by socio-affinity scoring ComPPI,IntAct
MAGEA2 DYNLRB1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
BCL2L1 DYNLRB1 10198631 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
PLOD3 DYNLRB1 25348397 N/A physical interaction ComPPI
FLNC DYNLRB1 25348397 N/A physical interaction ComPPI
CUL3 DYNLRB1 25348397 N/A physical interaction ComPPI
DYNC1LI1 DYNLRB1 25348397 N/A physical interaction ComPPI
MYC DYNLRB1 21150319 24234451 25348397 association tandem affinity purification ComPPI,IntAct
AKAP12 DYNLRB1 25348397 N/A physical interaction ComPPI
MPHOSPH8 DYNLRB1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
SEPTIN2 DYNLRB1 25348397 N/A physical interaction ComPPI
HSPH1 DYNLRB1 25348397 N/A physical interaction ComPPI
CENPJ DYNLRB1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
DYNC1H1 DYNLRB1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
DYNLT1 DYNLRB1 24234451 25348397 27173435 association,physical association physical interaction,tandem affinity purification,inference by socio-affinity scoring ComPPI,IntAct
PALS2 DYNLRB1 14525934 15231747 25348397 N/A two hybrid,physical interaction,two hybrid ComPPI,HPRD
MPHOSPH6 DYNLRB1 14525934 15231747 24234451 25348397 physical association two hybrid,two hybrid ComPPI,HPRD,IntAct
SAFB DYNLRB1 25348397 N/A physical interaction ComPPI
DCTN2 DYNLRB1 25348397 N/A physical interaction ComPPI
LAMTOR2 DYNLRB1 25348397 N/A physical interaction ComPPI
DYNC1I2 DYNLRB1 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
LNX1 DYNLRB1 25348397 N/A physical interaction ComPPI
CPEB1 DYNLRB1 12629046 14525934 25348397 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
DYNLRB1 DYNC1I1 14525934 16189514 24234451 25348397 physical association physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
DYNLRB1 MRPS26 25348397 N/A physical interaction ComPPI
DYNLRB1 DYNC1LI2 25348397 N/A physical interaction ComPPI
DYNLRB1 KIF11 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
DYNLRB1 CCDC88A 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
DYNLRB1 DYNLT2B 24234451 25348397 27173435 association,physical association physical interaction,tandem affinity purification,inference by socio-affinity scoring ComPPI,IntAct
DYNLRB1 PHLDA3 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
DYNLRB1 HLA-B 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
DYNLRB1 EPB41 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
DYNLRB1 TCTE1 24234451 25348397 26638075 association proximity-dependent biotin identification ComPPI,IntAct
DYNLRB1 SHLD3 24234451 25348397 29656893 association anti tag coimmunoprecipitation ComPPI,IntAct
PRKACA DYNLRB1 23333499 27898060 stimulant N/A OmniPath

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