Gene Information gene info

  1. Home

GENE：EARS2

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol EARS2
FullNmae glutamyl-tRNA synthetase 2, mitochondrial
LocusType gene with protein product
Status Approved
HGNC_id HGNC:29419
EnsembleID ENSG00000103356
Uniprot Q5JPH6

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
EARS2 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
EARS2 cuproptosis 36010978 Derived from the genome-wide CRISPR-Cas9 loss-of-function test reported in previous literature, 347 potential cuproptosis-related genes (FDR < 0.05) were identified, and for a detailed list of genes, see聽Supplementary Table S1. Cuproptosis-related genes

Go Annotation:

GeneSymbol Go id
EARS2 GO:0000049,GO:0004818,GO:0004818,GO:0005524,GO:0005739,GO:0005739,GO:0005759,GO:0006424,GO:0006424,GO:0008270,GO:0050561,GO:0070127

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
EARS2 hsa:124454 path:hsa00860 Porphyrin metabolism - Homo sapiens (human)
EARS2 hsa:124454 path:hsa00970 Aminoacyl-tRNA biosynthesis - Homo sapiens (human)
EARS2 hsa:124454 path:hsa01100 Metabolic pathways - Homo sapiens (human)
EARS2 hsa:124454 path:hsa01240 Biosynthesis of cofactors - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
E2F4 EARS2 17531812 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 EARS2 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
CEBPA EARS2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF EARS2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 EARS2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 EARS2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 EARS2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS EARS2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A EARS2 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00001597DC EARS2 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00003CF1AD EARS2 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00002075FA EARS2 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00002FC5B0 EARS2 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS00001A7F58 EARS2 22473208 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
KEAP1 EARS2 25348397 N/A physical interaction ComPPI
NTRK1 EARS2 25348397 N/A physical interaction ComPPI
MAS1 EARS2 25348397 N/A physical interaction ComPPI
BSG EARS2 25348397 N/A physical interaction ComPPI

Visualization










  Return