Gene Information gene info

  1. Home

GENE：CDK2AP1

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol CDK2AP1
FullNmae cyclin dependent kinase 2 associated protein 1
LocusType gene with protein product
Status Approved
HGNC_id HGNC:14002
EnsembleID ENSG00000111328
Uniprot O14519

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
CDK2AP1 necroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
CDK2AP1 GO:0000785,GO:0001934,GO:0005515,GO:0005634,GO:0005634,GO:0005654,GO:0005737,GO:0005829,GO:0006261,GO:0006357,GO:0007049,GO:0016581,GO:0048471,GO:0070182

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
CDK2AP1 hsa:8099 path:hsa03082 ATP-dependent chromatin remodeling - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
AR CDK2AP1 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
YBX1 CDK2AP1 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 CDK2AP1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF CDK2AP1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 CDK2AP1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A CDK2AP1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TAL1 CDK2AP1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TP53 CDK2AP1 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS000009262D CDK2AP1 21191961 21328460 rna interference,inhibition experimental interaction detection,western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay miRSponge
URS000009262D CDK2AP1 21328460 25416803 mrna cleavage,inhibition experimental interaction detection,western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase
URS000035CC3E CDK2AP1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000058276F CDK2AP1 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000017EE98 CDK2AP1 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000040EE1D CDK2AP1 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS0000080D0A CDK2AP1 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00004F507C CDK2AP1 25416803 27292025 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
IKBKE CDK2AP1 22135298 phosphorylation N/A PhosphoSite
CDK2AP1 CDK2 25361965 interaction type N/A PTMCode2
CDK2 CDK2AP1 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
GATAD2B CDK2AP1 24234451 25123934 25348397 26496610 association anti tag coimmunoprecipitation,pull down,physical interaction ComPPI,IntAct
CIAO1 CDK2AP1 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
SH3GLB1 CDK2AP1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
ATPAF2 CDK2AP1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
MRFAP1L1 CDK2AP1 21516116 24234451 25348397 25416956 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
VCP CDK2AP1 25348397 N/A physical interaction ComPPI
RPS15 CDK2AP1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
CDK2AP2 CDK2AP1 14525934 14985111 25348397 27898060 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD,OmniPath
ZNF219 CDK2AP1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PICK1 CDK2AP1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
TCF20 CDK2AP1 25348397 N/A physical interaction ComPPI
ZMYND8 CDK2AP1 25348397 N/A physical interaction ComPPI
POLA1 CDK2AP1 10877824 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
XRCC1 CDK2AP1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
HMG20A CDK2AP1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
RBBP4 CDK2AP1 24234451 25123934 25348397 27705803 association pull down,physical interaction,tandem affinity purification ComPPI,IntAct
WDR77 CDK2AP1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
CDK2 CDK2AP1 10938106 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
SPG21 CDK2AP1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
HDAC2 CDK2AP1 23752268 24234451 25123934 25348397 26496610 association anti tag coimmunoprecipitation,pull down,physical interaction ComPPI,IntAct
STRAP CDK2AP1 25348397 N/A physical interaction ComPPI
MTA1 CDK2AP1 24234451 25123934 25348397 26496610 association anti tag coimmunoprecipitation,pull down,physical interaction ComPPI,IntAct
MTA3 CDK2AP1 24234451 25123934 25348397 association pull down,physical interaction ComPPI,IntAct
BCOR CDK2AP1 25348397 N/A physical interaction ComPPI
CDK2AP1 AMY1C 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
CDK2AP1 SRRM2 25348397 N/A physical interaction ComPPI
CDK2AP1 HDAC1 23752268 24234451 25123934 25348397 26496610 association anti tag coimmunoprecipitation,pull down,physical interaction ComPPI,IntAct
CDK2AP1 RBBP7 24234451 25123934 25348397 26496610 27705803 association anti tag coimmunoprecipitation,pull down,physical interaction,tandem affinity purification ComPPI,IntAct
CDK2AP1 MBD3 24234451 25123934 25348397 26496610 association anti tag coimmunoprecipitation,pull down,physical interaction ComPPI,IntAct
CDK2AP1 MBD2 24234451 25123934 25348397 26496610 association anti tag coimmunoprecipitation,pull down,physical interaction ComPPI,IntAct
CDK2AP1 ELAVL1 25348397 N/A physical interaction ComPPI
CDK2AP1 ZNF420 21988832 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
CDK2AP1 CCDC136 25348397 N/A physical interaction ComPPI
CDK2AP1 MBD3L1 25348397 N/A physical interaction ComPPI
CDK2AP1 ALDOA 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
CDK2AP1 CHD3 24234451 25123934 25348397 26496610 28977666 association anti tag coimmunoprecipitation,pull down,physical interaction ComPPI,IntAct
CDK2AP1 CHD4 24234451 25123934 25348397 28977666 association anti tag coimmunoprecipitation,pull down,physical interaction ComPPI,IntAct
CDK2AP1 ERCC6 25348397 N/A physical interaction ComPPI
CDK2AP1 ERCC6 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
CDK2AP1 TRPS1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
CDK2AP1 MTA2 24234451 25123934 25348397 26496610 association anti tag coimmunoprecipitation,pull down,physical interaction ComPPI,IntAct
CDK2AP1 PHF14 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
CDK2AP1 RAI1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
CDK2AP1 ZBTB7B 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
CDK2AP1 ESF1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
CDK2AP1 GATAD2A 24234451 25123934 25348397 26496610 association anti tag coimmunoprecipitation,pull down,physical interaction ComPPI,IntAct
CDK2AP1 DDX60 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
CDK2AP1 TSR1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
CDK2AP1 TMEM165 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
CDK2AP1 ZNF687 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
CDK2AP1 ZBTB2 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
CDK2AP1 COPS7B 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
CDK2AP1 PGBD3 25348397 N/A physical interaction ComPPI
CDK2AP1 NANOGP8 25348397 N/A physical interaction ComPPI
CDK2AP1 NANOG 25348397 N/A physical interaction ComPPI
CDK2AP1 POU5F1 25348397 N/A physical interaction ComPPI
CDK2AP1 IGHA1 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
CDK2AP1 IGHA2 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
CDK2AP1 CSNK2B 10094392 24234451 25348397 physical association two hybrid ComPPI,IntAct
CDK2AP1 NTAQ1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
KPNA6 CDK2AP1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
LEO1 CDK2AP1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
CDK2AP1 CDK2AP1 24234451 25123934 association pull down IntAct
IKBKE CDK2AP1 22427660 27898060 N/A N/A OmniPath

Visualization










  Return