Gene Information gene info

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GENE：EMC6

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol EMC6
FullNmae ER membrane protein complex subunit 6
LocusType gene with protein product
Status Approved
HGNC_id HGNC:28430
EnsembleID ENSG00000127774
Uniprot Q9BV81

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
EMC6 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
EMC6 cuproptosis 38155776 Finally, EMC6 is indeed involved in the regulation of ferroptosis, cuproptosis, and immune response in LUAD. regulator

Go Annotation:

GeneSymbol Go id
EMC6 GO:0000045,GO:0000045,GO:0005515,GO:0005789,GO:0005789,GO:0016020,GO:0032977,GO:0045050,GO:0045050,GO:0071816,GO:0071816,GO:0072546,GO:0072546,GO:0072546,GO:0072546,GO:1903349

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
ETS1 EMC6 20019798 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
E2F1 EMC6 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS000003ABC4 EMC6 19088304 25416803 mrna cleavage,inhibition array technology TarBase
URS0000324096 EMC6 18668040 25416803 mrna cleavage,inhibition experimental interaction detection TarBase
URS00000AA464 EMC6 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00005651EE EMC6 23622248 25416803 mrna cleavage,inhibition clash TarBase

Source Target Pmid Interactiontype Methods Database
AQP9 EMC6 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
SLC7A1 EMC6 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
EMC2 EMC6 25348397 N/A physical interaction ComPPI
CREB3 EMC6 25348397 N/A physical interaction ComPPI
EBP EMC6 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
TRIM25 EMC6 25348397 N/A physical interaction ComPPI
CD79A EMC6 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
PDZK1IP1 EMC6 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
TARDBP EMC6 25348397 N/A physical interaction ComPPI
HLA-DRB1 EMC6 25348397 N/A physical interaction ComPPI

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