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GENE：ENTPD3

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol ENTPD3
FullNmae ectonucleoside triphosphate diphosphohydrolase 3
LocusType gene with protein product
Status Approved
HGNC_id HGNC:3365
EnsembleID ENSG00000168032
Uniprot O75355

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
ENTPD3 cuproptosis 36010978 Derived from the genome-wide CRISPR-Cas9 loss-of-function test reported in previous literature, 347 potential cuproptosis-related genes (FDR < 0.05) were identified, and for a detailed list of genes, see聽Supplementary Table S1. Cuproptosis-related genes

Go Annotation:

GeneSymbol Go id
ENTPD3 GO:0004382,GO:0005515,GO:0005524,GO:0005886,GO:0005886,GO:0009134,GO:0009143,GO:0017110,GO:0017111,GO:0045134

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
ENTPD3 hsa:956 path:hsa00230 Purine metabolism - Homo sapiens (human)
ENTPD3 hsa:956 path:hsa00240 Pyrimidine metabolism - Homo sapiens (human)
ENTPD3 hsa:956 path:hsa01100 Metabolic pathways - Homo sapiens (human)
ENTPD3 hsa:956 path:hsa01232 Nucleotide metabolism - Homo sapiens (human)
ENTPD3 hsa:956 path:hsa05169 Epstein-Barr virus infection - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
GATA2 ENTPD3 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
YBX1 ENTPD3 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 ENTPD3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 ENTPD3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 ENTPD3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 ENTPD3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS ENTPD3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A ENTPD3 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00000B59A2 ENTPD3 16822819 25416803 mrna cleavage,inhibition array technology TarBase
URS0000237AF9 ENTPD3 18185580 25416803 mrna cleavage,inhibition array technology TarBase

Source Target Pmid Interactiontype Methods Database
LMNA ENTPD3 25348397 N/A physical interaction ComPPI

Visualization










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