Gene Information gene info

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GENE：EXOC3

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol EXOC3
FullNmae exocyst complex component 3
LocusType gene with protein product
Status Approved
HGNC_id HGNC:30378
EnsembleID ENSG00000180104
Uniprot O60645

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
EXOC3 cuproptosis 36010978 Derived from the genome-wide CRISPR-Cas9 loss-of-function test reported in previous literature, 347 potential cuproptosis-related genes (FDR < 0.05) were identified, and for a detailed list of genes, see聽Supplementary Table S1. Cuproptosis-related genes

Go Annotation:

GeneSymbol Go id
EXOC3 GO:0000145,GO:0000145,GO:0000149,GO:0000281,GO:0005515,GO:0005794,GO:0005829,GO:0006887,GO:0006904,GO:0015031,GO:0030426,GO:0030496,GO:0030667,GO:0042734,GO:0045296,GO:0048471,GO:0051601,GO:0090148,GO:0090522

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
EXOC3 EXOC4 17018283 23180781 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
CTCF EXOC3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 EXOC3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 EXOC3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF EXOC3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
VDR EXOC3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ATF1 EXOC3 N/A trascriptional regulation,stimulation inferred by curator TFlink
JUN EXOC3 N/A trascriptional regulation,stimulation inferred by curator TFlink
POU2F1 EXOC3 N/A trascriptional regulation,stimulation inferred by curator TFlink
SP1 EXOC3 N/A trascriptional regulation,stimulation inferred by curator TFlink
STAT1 EXOC3 N/A trascriptional regulation,stimulation inferred by curator TFlink
STAT3 EXOC3 N/A trascriptional regulation,stimulation inferred by curator TFlink
STAT5A EXOC3 N/A trascriptional regulation,stimulation inferred by curator TFlink
STAT5B EXOC3 N/A trascriptional regulation,stimulation inferred by curator TFlink
TFAP2A EXOC3 N/A trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000338542 EXOC3 18668040 25416803 mrna cleavage,inhibition experimental interaction detection TarBase

Source Target Pmid Interactiontype Methods Database
EXOC5 EXOC3 24234451 25348397 27173435 association,physical association physical interaction,tandem affinity purification,inference by socio-affinity scoring ComPPI,IntAct
SNW1 EXOC3 20467437 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
VAMP2 EXOC3 25348397 N/A physical interaction ComPPI
PTPRH EXOC3 25348397 N/A physical interaction ComPPI
TRIM32 EXOC3 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
EXOC8 EXOC3 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
KXD1 EXOC3 25348397 N/A physical interaction ComPPI
SDC2 EXOC3 25348397 N/A physical interaction ComPPI
NTRK1 EXOC3 25348397 N/A physical interaction ComPPI
CDH1 EXOC3 25348397 N/A physical interaction ComPPI
BUB3 EXOC3 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
PKD2 EXOC3 25348397 N/A physical interaction ComPPI
PTPRA EXOC3 25348397 N/A physical interaction ComPPI
MYC EXOC3 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
RALA EXOC3 11406615 14525934 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
MKNK2 EXOC3 25348397 N/A physical interaction ComPPI
EXOC1 EXOC3 24234451 25348397 27173435 association,physical association physical interaction,tandem affinity purification,inference by socio-affinity scoring ComPPI,IntAct
EXOC3 EXOC2 14525934 14525976 24234451 25348397 27173435 association,physical association two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,tandem affinity purification,inference by socio-affinity scoring,two hybrid ComPPI,HPRD,IntAct
EXOC3 BIRC6 14525934 18329369 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
EXOC3 EXOC4 24234451 25348397 27173435 association,physical association physical interaction,tandem affinity purification,inference by socio-affinity scoring ComPPI,IntAct
EXOC3 DLG3 25348397 N/A physical interaction ComPPI
EXOC3 GRIN2B 25348397 N/A physical interaction ComPPI
EXOC3 MYO5A 25348397 N/A physical interaction ComPPI
EXOC3 APP 25348397 N/A physical interaction ComPPI
EXOC3 EXOC6 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
EXOC3 MLH1 20706999 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
EXOC3 EGFR 24234451 25348397 25594178 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
EXOC3 PRPF19 25348397 N/A physical interaction ComPPI
EXOC3 KHDC4 25348397 N/A physical interaction ComPPI
EXOC3 CCDC8 25348397 N/A physical interaction ComPPI
EXOC3 BSG 25348397 N/A physical interaction ComPPI
EXOC3 DTNBP1 25348397 N/A physical interaction ComPPI
EXOC3 EXOC7 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
EXOC3 METAP1 25348397 N/A physical interaction ComPPI
EXOC3 TRMT2A 25348397 N/A physical interaction ComPPI
EXOC3 TMEM17 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
EXOC3 KIF2A 25348397 N/A physical interaction ComPPI
EXOC3 GCC2 25348397 N/A physical interaction ComPPI
EXOC3 TRIP11 25348397 N/A physical interaction ComPPI
EXOC3 SCLT1 25348397 N/A physical interaction ComPPI
EXOC3 EXOC6B 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
EXOC3 KIZ 25348397 N/A physical interaction ComPPI
EXOC3 KLC2 25348397 N/A physical interaction ComPPI
EXOC3 IL1R2 25348397 N/A physical interaction ComPPI
EXOC3 IFT20 25348397 N/A physical interaction ComPPI
EXOC3 KIF3A 25348397 N/A physical interaction ComPPI
EXOC3 CCDC136 25348397 N/A physical interaction ComPPI
EXOC3 PIBF1 25348397 N/A physical interaction ComPPI
EXOC3 KLC1 25348397 N/A physical interaction ComPPI
EXOC3 COA8 25348397 N/A physical interaction ComPPI
EXOC3 RGPD2 25348397 N/A physical interaction ComPPI
EXOC3 MACROD1 25348397 N/A physical interaction ComPPI
EXOC3 RGPD5 25348397 N/A physical interaction ComPPI
EXOC3 TMED1 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
EXOC3 RALB 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
EXOC3 TULP3 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
EXOC3 TRIM25 25348397 N/A physical interaction ComPPI
EXOC3 ZUP1 25348397 N/A physical interaction ComPPI
EXOC3 LAPTM4B 24234451 25348397 25594178 physical association anti tag coimmunoprecipitation ComPPI,IntAct
HNRNPA1L2 EXOC3 24234451 30021884 physical association cross-linking study IntAct

Source Target Pmid Interactiontype Methods Database
URS00008B5296 EXOC3 27087310 direct interaction,inhibition N/A NPInter

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