GeneInfo:
GeneAttribute
GeneDescription
GeneSymbol
FAM111A
FullNmae
FAM111 trypsin like peptidase A
LocusType
gene with protein product
Status
Approved
HGNC_id
HGNC:24725
EnsembleID
ENSG00000166801
Uniprot
Q96PZ2
Protein Structure:
Gene Description in Publicaton:
GeneSymbol
CellDeathType
PMID
Description
GeneType
FAM111A
cuproptosis
36010978
Derived from the genome-wide CRISPR-Cas9 loss-of-function test reported in previous literature, 347 potential cuproptosis-related genes (FDR < 0.05) were identified, and for a detailed list of genes, see聽Supplementary Table S1.
Cuproptosis-related genes
Go Annotation:
GeneSymbol
Go id
FAM111A
GO:0000785,GO:0000785,GO:0001650,GO:0003697,GO:0005515,GO:0005634,GO:0005634,GO:0005654,GO:0005737,GO:0006260,GO:0006260,GO:0006508,GO:0006974,GO:0008233,GO:0016540,GO:0031297,GO:0045071,GO:0106300
Protein-Protein Interaction(String):
Signalink 3.0 modificators
Source
Target
Pmid
Interactiontype
Methods
Database
AR
FAM111A
20610535
trascriptional regulation,stimulation
chromatin immunoprecipitation array
TFlink
E2F4
FAM111A
17531812
18971253
trascriptional regulation,stimulation
chromatin immunoprecipitation array,inferred by curator
TFlink
ETS1
FAM111A
18971253
20019798
trascriptional regulation,stimulation
inferred by curator,chromatin immunoprecipitation assay
TFlink
YBX1
FAM111A
19151767
trascriptional regulation,stimulation
chromatin immunoprecipitation assay
TFlink
FOXP3
FAM111A
20554955
trascriptional regulation,stimulation
chromatin immunoprecipitation array
TFlink
SMARCA4
FAM111A
18971253
trascriptional regulation,stimulation
inferred by curator
TFlink
CEBPA
FAM111A
18971253
trascriptional regulation,stimulation
inferred by curator
TFlink
CTCF
FAM111A
18971253
trascriptional regulation,stimulation
inferred by curator
TFlink
EGR1
FAM111A
18971253
trascriptional regulation,stimulation
inferred by curator
TFlink
Source
Target
Pmid
Interactiontype
Methods
Database
URS00000AA464
FAM111A
20304954
25416803
mrna cleavage,inhibition
array technology
TarBase
Source
Target
Pmid
Interactiontype
Methods
Database
HNRNPL
FAM111A
25348397
N/A
physical interaction
ComPPI
NCSTN
FAM111A
24234451
25348397
26496610
association
anti tag coimmunoprecipitation,physical interaction
ComPPI,IntAct
NOP56
FAM111A
24234451
25348397
26496610
association
anti tag coimmunoprecipitation,physical interaction
ComPPI,IntAct
BRCA1
FAM111A
24234451
25348397
29656893
association
proximity-dependent biotin identification
ComPPI,IntAct
CDC23
FAM111A
24234451
25348397
26496610
association
anti tag coimmunoprecipitation,physical interaction
ComPPI,IntAct
TP53
FAM111A
25348397
N/A
physical interaction
ComPPI
MKI67
FAM111A
24234451
26949251
association
anti tag coimmunoprecipitation
IntAct
SF3A1
FAM111A
24234451
30021884
physical association
cross-linking study
IntAct
Visualization