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GENE：GADD45GIP1

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol GADD45GIP1
FullNmae GADD45G interacting protein 1
LocusType gene with protein product
Status Approved
HGNC_id HGNC:29996
EnsembleID ENSG00000179271
Uniprot Q8TAE8

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
GADD45GIP1 mitotic_cd 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
GADD45GIP1 cuproptosis 36010978 Derived from the genome-wide CRISPR-Cas9 loss-of-function test reported in previous literature, 347 potential cuproptosis-related genes (FDR < 0.05) were identified, and for a detailed list of genes, see聽Supplementary Table S1. Cuproptosis-related genes

Go Annotation:

GeneSymbol Go id
GADD45GIP1 GO:0005515,GO:0005654,GO:0005739,GO:0005739,GO:0005743,GO:0005759,GO:0005762,GO:0007049,GO:0032543

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
IKBKG GADD45GIP1 20098747 23180781 physical association protein array InnateDB
APP GADD45GIP1 21832049 23180781 physical association protein array InnateDB

Source Target Pmid Interactiontype Methods Database
ETS1 GADD45GIP1 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
HIF1A GADD45GIP1 18971253 19828020 trascriptional regulation,stimulation chromatin immunoprecipitation array,inferred by curator TFlink
SMARCA4 GADD45GIP1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF GADD45GIP1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 GADD45GIP1 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS000003ABC4 GADD45GIP1 19088304 25416803 mrna cleavage,inhibition array technology TarBase
URS00003D5391 GADD45GIP1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000070B1D GADD45GIP1 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS0000214763 GADD45GIP1 19536157 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
CSNK2A1 GADD45GIP1 22135298 phosphorylation N/A PhosphoSite
GADD45GIP1 GADD45A 25361965 interaction type N/A PTMCode2
GADD45A GADD45GIP1 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
GEM GADD45GIP1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
GOLGA2 GADD45GIP1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
OIP5 GADD45GIP1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
PBX4 GADD45GIP1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
GADD45G GADD45GIP1 12716909 14525934 24234451 25348397 physical association anti tag coimmunoprecipitation,two hybrid,experimental interaction detection,pull down,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD,IntAct
LDOC1 GADD45GIP1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
LZTS2 GADD45GIP1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
MAGEA6 GADD45GIP1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
FOXB1 GADD45GIP1 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
MRPL28 GADD45GIP1 25348397 N/A physical interaction ComPPI
MKRN3 GADD45GIP1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
PTPN6 GADD45GIP1 25348397 N/A physical interaction ComPPI
NIFK GADD45GIP1 25348397 N/A physical interaction ComPPI
KRT31 GADD45GIP1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
SMN1 GADD45GIP1 25348397 N/A two hybrid ComPPI
KRT40 GADD45GIP1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
PNMA1 GADD45GIP1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
GPRASP2 GADD45GIP1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
PICK1 GADD45GIP1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
AR GADD45GIP1 25348397 N/A physical interaction ComPPI
COPS5 GADD45GIP1 25348397 N/A physical interaction ComPPI
NFE2L2 GADD45GIP1 25348397 N/A physical interaction ComPPI
MTMR10 GADD45GIP1 25348397 N/A physical interaction ComPPI
TAP1 GADD45GIP1 25348397 N/A physical interaction ComPPI
GADD45B GADD45GIP1 12716909 14525934 25348397 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD
PTPN2 GADD45GIP1 25348397 N/A physical interaction ComPPI
WWP2 GADD45GIP1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
TNS2 GADD45GIP1 25348397 N/A physical interaction ComPPI
HMG20A GADD45GIP1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
EIF3C GADD45GIP1 25348397 N/A physical interaction ComPPI
PTP4A2 GADD45GIP1 25348397 N/A physical interaction ComPPI
TRAF1 GADD45GIP1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
ABCE1 GADD45GIP1 25348397 N/A physical interaction ComPPI
UPF2 GADD45GIP1 25348397 N/A physical interaction ComPPI
SPTA1 GADD45GIP1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
NR4A1 GADD45GIP1 14525934 15459248 25348397 N/A two hybrid,experimental interaction detection,physical interaction,in vivo,two hybrid ComPPI,HPRD
CDC14B GADD45GIP1 25348397 N/A physical interaction ComPPI
H3C1 GADD45GIP1 25348397 N/A physical interaction ComPPI
EXOSC4 GADD45GIP1 14525934 15231747 24234451 25348397 physical association two hybrid,physical interaction,two hybrid ComPPI,HPRD,IntAct
TFIP11 GADD45GIP1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
PTRH2 GADD45GIP1 25348397 N/A physical interaction ComPPI
TRIM25 GADD45GIP1 25348397 N/A physical interaction ComPPI
DVL3 GADD45GIP1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
TRIM27 GADD45GIP1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
PTP4A1 GADD45GIP1 25348397 N/A physical interaction ComPPI
STAT3 GADD45GIP1 18200042 24234451 25348397 25416956 27898060 physical association anti tag coimmunoprecipitation,two hybrid,mammalian protein protein interaction trap ComPPI,IntAct,OmniPath
RPL13 GADD45GIP1 25348397 N/A physical interaction ComPPI
PSMB1 GADD45GIP1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
ELF3 GADD45GIP1 19801644 25348397 27898060 N/A physical interaction ComPPI,OmniPath
ZRANB1 GADD45GIP1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
FOXL2 GADD45GIP1 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
RBM11 GADD45GIP1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
AURKAIP1 GADD45GIP1 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
FBXW11 GADD45GIP1 25348397 N/A physical interaction ComPPI
RNGTT GADD45GIP1 25348397 N/A physical interaction ComPPI
CARD10 GADD45GIP1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
MTMR2 GADD45GIP1 25348397 N/A physical interaction ComPPI
RAB5C GADD45GIP1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
CSNK2B GADD45GIP1 11710515 14525934 25348397 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,two hybrid ComPPI,HPRD
GADD45GIP1 GADD45A 12716909 14525934 24234451 25348397 physical association anti tag coimmunoprecipitation,two hybrid,experimental interaction detection,pull down,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD,IntAct
GADD45GIP1 IKBKG 20098747 24234451 25348397 N/A protein array,physical interaction ComPPI,IntAct
GADD45GIP1 MRPL58 20186120 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
GADD45GIP1 HNRNPA1 25348397 N/A physical interaction ComPPI
GADD45GIP1 APP 25348397 N/A physical interaction ComPPI
GADD45GIP1 SLC25A10 25348397 N/A physical interaction ComPPI
GADD45GIP1 TSR1 25348397 N/A physical interaction ComPPI
GADD45GIP1 TMEM177 25348397 N/A physical interaction ComPPI
GADD45GIP1 MRPL11 25348397 N/A physical interaction ComPPI
GADD45GIP1 MRPL14 25348397 N/A physical interaction ComPPI
GADD45GIP1 LIN28A 25348397 N/A physical interaction ComPPI
GADD45GIP1 CCDC8 25348397 N/A physical interaction ComPPI
GADD45GIP1 RPS8 25348397 N/A physical interaction ComPPI
GADD45GIP1 MRPL37 25348397 N/A physical interaction ComPPI
GADD45GIP1 MRPS30 25348397 N/A physical interaction ComPPI
GADD45GIP1 MRPL47 25348397 N/A physical interaction ComPPI
GADD45GIP1 KIF2A 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
GADD45GIP1 MRPL50 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
GADD45GIP1 KRBOX4 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
GADD45GIP1 FOXL1 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
GADD45GIP1 FOXS1 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
GADD45GIP1 ACP1 25348397 N/A physical interaction ComPPI
GADD45GIP1 FAN1 25348397 N/A physical interaction ComPPI
GADD45GIP1 MRPL42 25348397 N/A physical interaction ComPPI
GADD45GIP1 MRPL41 25348397 N/A physical interaction ComPPI
GADD45GIP1 MRPL10 25348397 N/A physical interaction ComPPI
GADD45GIP1 ZC3HAV1 25348397 N/A physical interaction ComPPI
GADD45GIP1 MAGEA11 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
GADD45GIP1 MRPL38 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
GADD45GIP1 BPIFA1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
GADD45GIP1 MIPOL1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
GADD45GIP1 CCNC 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
GADD45GIP1 KRT34 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
GADD45GIP1 GAS8 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
GADD45GIP1 ENKD1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
GADD45GIP1 NTAQ1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
GADD45GIP1 KANK2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
GADD45GIP1 NFKBID 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
GADD45GIP1 CEP70 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
GADD45GIP1 LRRC73 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
GADD45GIP1 GOLGA6A 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
GADD45GIP1 ANKRD28 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
GADD45GIP1 PRDM6 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
GADD45GIP1 KRT27 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
GADD45GIP1 GOLGA6L9 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
GADD45GIP1 KSR1 24234451 25348397 27086506 association anti tag coimmunoprecipitation ComPPI,IntAct
MRPL4 GADD45GIP1 25348397 N/A physical interaction ComPPI
MGST3 GADD45GIP1 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
MRPL12 GADD45GIP1 25348397 N/A physical interaction ComPPI
MRPL9 GADD45GIP1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
TRMT61B GADD45GIP1 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
MRPL1 GADD45GIP1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
HSCB GADD45GIP1 24234451 25348397 28380382 association anti bait coimmunoprecipitation ComPPI,IntAct
MYG1 GADD45GIP1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
GADD45GIP1 NEXN 24234451 30021884 physical association cross-linking study IntAct
IKBKG GADD45GIP1 20098747 27898060 N/A N/A OmniPath
GADD45GIP1 NFE2L2 20427290 27898060 inhibition N/A OmniPath
CSNK2A1 GADD45GIP1 17069992 27898060 N/A N/A OmniPath

Visualization










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