Gene Information gene info

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GENE：GATB

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol GATB
FullNmae glutamyl-tRNA amidotransferase subunit B
LocusType gene with protein product
Status Approved
HGNC_id HGNC:8849
EnsembleID ENSG00000059691
Uniprot O75879

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
GATB cuproptosis 36010978 Derived from the genome-wide CRISPR-Cas9 loss-of-function test reported in previous literature, 347 potential cuproptosis-related genes (FDR < 0.05) were identified, and for a detailed list of genes, see聽Supplementary Table S1. Cuproptosis-related genes

Go Annotation:

GeneSymbol Go id
GATB GO:0005515,GO:0005524,GO:0005739,GO:0005739,GO:0005739,GO:0030956,GO:0030956,GO:0030956,GO:0032543,GO:0032543,GO:0050567,GO:0050567,GO:0070681,GO:0070681

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
GATB hsa:5188 path:hsa00970 Aminoacyl-tRNA biosynthesis - Homo sapiens (human)
GATB hsa:5188 path:hsa01100 Metabolic pathways - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
AR GATB 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 GATB 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA1 GATB 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA2 GATB 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
YBX1 GATB 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 GATB 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF GATB 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 GATB 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 GATB 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS GATB 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A GATB 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF GATB 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 GATB 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00000B59A2 GATB 19074876 25416803 mrna cleavage,inhibition array technology TarBase
URS000000B1C9 GATB 23622248 25416803 mrna cleavage,inhibition clash TarBase

Source Target Pmid Interactiontype Methods Database
SLAMF1 GATB 25348397 N/A physical interaction ComPPI
LRP1 GATB 25348397 N/A physical interaction ComPPI
PDK1 GATB 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
AURKAIP1 GATB 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
HSPD1 GATB 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
SLC25A10 GATB 25348397 N/A physical interaction ComPPI
MRPL12 GATB 25348397 N/A physical interaction ComPPI
IL13RA2 GATB 25348397 N/A physical interaction ComPPI
MUC20 GATB 25348397 N/A physical interaction ComPPI
TRMT61B GATB 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct

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