GeneInfo:
GeneAttribute
GeneDescription
GeneSymbol
GFM1
FullNmae
G elongation factor mitochondrial 1
LocusType
gene with protein product
Status
Approved
HGNC_id
HGNC:13780
EnsembleID
ENSG00000168827
Uniprot
Q96RP9
Protein Structure:
Gene Description in Publicaton:
GeneSymbol
CellDeathType
PMID
Description
GeneType
GFM1
cuproptosis
36010978
Derived from the genome-wide CRISPR-Cas9 loss-of-function test reported in previous literature, 347 potential cuproptosis-related genes (FDR < 0.05) were identified, and for a detailed list of genes, see聽Supplementary Table S1.
Cuproptosis-related genes
Go Annotation:
GeneSymbol
Go id
GFM1
GO:0003723,GO:0003746,GO:0003746,GO:0003924,GO:0003924,GO:0005515,GO:0005525,GO:0005739,GO:0005759,GO:0070125,GO:0070125
Protein-Protein Interaction(String):
Signalink 3.0 modificators
Source
Target
Pmid
Interactiontype
Methods
Database
ADRB2
GFM1
23180781
23798571
physical association
anti tag coimmunoprecipitation
InnateDB
Source
Target
Pmid
Interactiontype
Methods
Database
AR
GFM1
20610535
trascriptional regulation,stimulation
chromatin immunoprecipitation array
TFlink
ETS1
GFM1
18971253
20019798
trascriptional regulation,stimulation
inferred by curator,chromatin immunoprecipitation assay
TFlink
GATA2
GFM1
19941826
trascriptional regulation,stimulation
chromatin immunoprecipitation assay
TFlink
YBX1
GFM1
19151767
trascriptional regulation,stimulation
chromatin immunoprecipitation assay
TFlink
SMARCA4
GFM1
18971253
trascriptional regulation,stimulation
inferred by curator
TFlink
CTCF
GFM1
18971253
trascriptional regulation,stimulation
inferred by curator
TFlink
E2F1
GFM1
18971253
trascriptional regulation,stimulation
inferred by curator
TFlink
FOXA1
GFM1
18971253
trascriptional regulation,stimulation
inferred by curator
TFlink
FOS
GFM1
18971253
trascriptional regulation,stimulation
inferred by curator
TFlink
HNF4A
GFM1
18971253
trascriptional regulation,stimulation
inferred by curator
TFlink
MITF
GFM1
18971253
trascriptional regulation,stimulation
inferred by curator
TFlink
Source
Target
Pmid
Interactiontype
Methods
Database
URS000024CEE0
GFM1
25416803
27292025
mrna cleavage,inhibition
clip
TarBase
URS000075994C
GFM1
25416803
27292025
mrna cleavage,inhibition
clip
TarBase
Source
Target
Pmid
Interactiontype
Methods
Database
TSFM
GFM1
25361965
interaction type
N/A
PTMCode2
GFM1
TSFM
25361965
interaction type
N/A
PTMCode2
RPS16
GFM1
25361965
interaction type
N/A
PTMCode2
GFM1
RPS16
25361965
interaction type
N/A
PTMCode2
RPL8
GFM1
25361965
interaction type
N/A
PTMCode2
GFM1
RPL8
25361965
interaction type
N/A
PTMCode2
RPS5
GFM1
25361965
interaction type
N/A
PTMCode2
GFM1
RPS5
25361965
interaction type
N/A
PTMCode2
RPL23
GFM1
25361965
interaction type
N/A
PTMCode2
GFM1
RPL23
25361965
interaction type
N/A
PTMCode2
MRPS16
GFM1
25361965
interaction type
N/A
PTMCode2
GFM1
MRPS16
25361965
interaction type
N/A
PTMCode2
MRPL3
GFM1
25361965
interaction type
N/A
PTMCode2
GFM1
MRPL3
25361965
interaction type
N/A
PTMCode2
MRPL17
GFM1
25361965
interaction type
N/A
PTMCode2
GFM1
MRPL17
25361965
interaction type
N/A
PTMCode2
RPL11
GFM1
25361965
interaction type
N/A
PTMCode2
GFM1
RPL11
25361965
interaction type
N/A
PTMCode2
MRPL4
GFM1
25361965
interaction type
N/A
PTMCode2
GFM1
MRPL4
25361965
interaction type
N/A
PTMCode2
RPS14
GFM1
25361965
interaction type
N/A
PTMCode2
GFM1
RPS14
25361965
interaction type
N/A
PTMCode2
MRPS11
GFM1
25361965
interaction type
N/A
PTMCode2
GFM1
MRPS11
25361965
interaction type
N/A
PTMCode2
MRPL13
GFM1
25361965
interaction type
N/A
PTMCode2
GFM1
MRPL13
25361965
interaction type
N/A
PTMCode2
MRPS7
GFM1
25361965
interaction type
N/A
PTMCode2
GFM1
MRPS7
25361965
interaction type
N/A
PTMCode2
TUFM
GFM1
25361965
interaction type
N/A
PTMCode2
GFM1
TUFM
25361965
interaction type
N/A
PTMCode2
MRPL2
GFM1
25361965
interaction type
N/A
PTMCode2
GFM1
MRPL2
25361965
interaction type
N/A
PTMCode2
MRPL11
GFM1
25361965
interaction type
N/A
PTMCode2
GFM1
MRPL11
25361965
interaction type
N/A
PTMCode2
MRPL16
GFM1
25361965
interaction type
N/A
PTMCode2
GFM1
MRPL16
25361965
interaction type
N/A
PTMCode2
Source
Target
Pmid
Interactiontype
Methods
Database
MAGOHB
GFM1
24234451
25348397
26496610
association
anti tag coimmunoprecipitation,physical interaction
ComPPI,IntAct
BOLA1
GFM1
25348397
N/A
physical interaction
ComPPI
FASTKD3
GFM1
20869947
24234451
25348397
association
tandem affinity purification
ComPPI,IntAct
KEAP1
GFM1
25348397
N/A
physical interaction
ComPPI
TUFM
GFM1
25348397
N/A
physical interaction
ComPPI
SMURF2
GFM1
18157088
24234451
25348397
physical association
two hybrid
ComPPI,IntAct
NTRK1
GFM1
25348397
N/A
physical interaction
ComPPI
NIT1
GFM1
24234451
25348397
27499296
association
anti tag coimmunoprecipitation
ComPPI,IntAct
MAPK13
GFM1
19135240
24234451
25348397
association
anti tag coimmunoprecipitation
ComPPI,IntAct
ADRB2
GFM1
25348397
N/A
physical interaction
ComPPI
TRIM63
GFM1
18157088
24234451
25348397
physical association
two hybrid,pull down,physical interaction
ComPPI,IntAct
SUCLA2
GFM1
25348397
N/A
physical interaction
ComPPI
PDK1
GFM1
24234451
25348397
29568061
association
proximity-dependent biotin identification
ComPPI,IntAct
ECSIT
GFM1
25348397
N/A
physical interaction
ComPPI
NDUFS7
GFM1
25348397
N/A
physical interaction
ComPPI
RPL23A
GFM1
25348397
N/A
physical interaction
ComPPI
TRIM55
GFM1
18157088
24234451
25348397
physical association
pull down,physical interaction
ComPPI,IntAct
HSPD1
GFM1
24234451
25348397
29568061
association
physical interaction,proximity-dependent biotin identification
ComPPI,IntAct
DUSP13
GFM1
25348397
N/A
physical interaction
ComPPI
SLC25A10
GFM1
25348397
N/A
physical interaction
ComPPI
MGST3
GFM1
24234451
25348397
29568061
association
proximity-dependent biotin identification
ComPPI,IntAct
MRPL12
GFM1
25348397
N/A
physical interaction
ComPPI
SLX4
GFM1
19596235
24234451
25348397
association
anti tag coimmunoprecipitation
ComPPI,IntAct
DUSP13
GFM1
25348397
N/A
physical interaction
ComPPI
MRPS7
GFM1
25348397
N/A
physical interaction
ComPPI
TRMT61B
GFM1
24234451
25348397
29568061
association
proximity-dependent biotin identification
ComPPI,IntAct
NDUFS3
GFM1
25348397
N/A
physical interaction
ComPPI
YBEY
GFM1
25348397
N/A
physical interaction
ComPPI
GFM1
BOLA3
24234451
25348397
27499296
association
anti tag coimmunoprecipitation
ComPPI,IntAct
Visualization