Gene Information gene info

GENE:GFM1

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol GFM1
FullNmae G elongation factor mitochondrial 1
LocusType gene with protein product
Status Approved
HGNC_id HGNC:13780
EnsembleID ENSG00000168827
Uniprot Q96RP9

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
GFM1 cuproptosis 36010978 Derived from the genome-wide CRISPR-Cas9 loss-of-function test reported in previous literature, 347 potential cuproptosis-related genes (FDR < 0.05) were identified, and for a detailed list of genes, see聽Supplementary Table S1. Cuproptosis-related genes

Go Annotation:

GeneSymbol Go id
GFM1 GO:0003723,GO:0003746,GO:0003746,GO:0003924,GO:0003924,GO:0005515,GO:0005525,GO:0005739,GO:0005759,GO:0070125,GO:0070125

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
ADRB2 GFM1 23180781 23798571 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
AR GFM1 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 GFM1 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA2 GFM1 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
YBX1 GFM1 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 GFM1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF GFM1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 GFM1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 GFM1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS GFM1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A GFM1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF GFM1 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS000024CEE0 GFM1 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000075994C GFM1 25416803 27292025 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
TSFM GFM1 25361965 interaction type N/A PTMCode2
GFM1 TSFM 25361965 interaction type N/A PTMCode2
RPS16 GFM1 25361965 interaction type N/A PTMCode2
GFM1 RPS16 25361965 interaction type N/A PTMCode2
RPL8 GFM1 25361965 interaction type N/A PTMCode2
GFM1 RPL8 25361965 interaction type N/A PTMCode2
RPS5 GFM1 25361965 interaction type N/A PTMCode2
GFM1 RPS5 25361965 interaction type N/A PTMCode2
RPL23 GFM1 25361965 interaction type N/A PTMCode2
GFM1 RPL23 25361965 interaction type N/A PTMCode2
MRPS16 GFM1 25361965 interaction type N/A PTMCode2
GFM1 MRPS16 25361965 interaction type N/A PTMCode2
MRPL3 GFM1 25361965 interaction type N/A PTMCode2
GFM1 MRPL3 25361965 interaction type N/A PTMCode2
MRPL17 GFM1 25361965 interaction type N/A PTMCode2
GFM1 MRPL17 25361965 interaction type N/A PTMCode2
RPL11 GFM1 25361965 interaction type N/A PTMCode2
GFM1 RPL11 25361965 interaction type N/A PTMCode2
MRPL4 GFM1 25361965 interaction type N/A PTMCode2
GFM1 MRPL4 25361965 interaction type N/A PTMCode2
RPS14 GFM1 25361965 interaction type N/A PTMCode2
GFM1 RPS14 25361965 interaction type N/A PTMCode2
MRPS11 GFM1 25361965 interaction type N/A PTMCode2
GFM1 MRPS11 25361965 interaction type N/A PTMCode2
MRPL13 GFM1 25361965 interaction type N/A PTMCode2
GFM1 MRPL13 25361965 interaction type N/A PTMCode2
MRPS7 GFM1 25361965 interaction type N/A PTMCode2
GFM1 MRPS7 25361965 interaction type N/A PTMCode2
TUFM GFM1 25361965 interaction type N/A PTMCode2
GFM1 TUFM 25361965 interaction type N/A PTMCode2
MRPL2 GFM1 25361965 interaction type N/A PTMCode2
GFM1 MRPL2 25361965 interaction type N/A PTMCode2
MRPL11 GFM1 25361965 interaction type N/A PTMCode2
GFM1 MRPL11 25361965 interaction type N/A PTMCode2
MRPL16 GFM1 25361965 interaction type N/A PTMCode2
GFM1 MRPL16 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
MAGOHB GFM1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
BOLA1 GFM1 25348397 N/A physical interaction ComPPI
FASTKD3 GFM1 20869947 24234451 25348397 association tandem affinity purification ComPPI,IntAct
KEAP1 GFM1 25348397 N/A physical interaction ComPPI
TUFM GFM1 25348397 N/A physical interaction ComPPI
SMURF2 GFM1 18157088 24234451 25348397 physical association two hybrid ComPPI,IntAct
NTRK1 GFM1 25348397 N/A physical interaction ComPPI
NIT1 GFM1 24234451 25348397 27499296 association anti tag coimmunoprecipitation ComPPI,IntAct
MAPK13 GFM1 19135240 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
ADRB2 GFM1 25348397 N/A physical interaction ComPPI
TRIM63 GFM1 18157088 24234451 25348397 physical association two hybrid,pull down,physical interaction ComPPI,IntAct
SUCLA2 GFM1 25348397 N/A physical interaction ComPPI
PDK1 GFM1 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
ECSIT GFM1 25348397 N/A physical interaction ComPPI
NDUFS7 GFM1 25348397 N/A physical interaction ComPPI
RPL23A GFM1 25348397 N/A physical interaction ComPPI
TRIM55 GFM1 18157088 24234451 25348397 physical association pull down,physical interaction ComPPI,IntAct
HSPD1 GFM1 24234451 25348397 29568061 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
DUSP13 GFM1 25348397 N/A physical interaction ComPPI
SLC25A10 GFM1 25348397 N/A physical interaction ComPPI
MGST3 GFM1 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
MRPL12 GFM1 25348397 N/A physical interaction ComPPI
SLX4 GFM1 19596235 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
DUSP13 GFM1 25348397 N/A physical interaction ComPPI
MRPS7 GFM1 25348397 N/A physical interaction ComPPI
TRMT61B GFM1 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
NDUFS3 GFM1 25348397 N/A physical interaction ComPPI
YBEY GFM1 25348397 N/A physical interaction ComPPI
GFM1 BOLA3 24234451 25348397 27499296 association anti tag coimmunoprecipitation ComPPI,IntAct

Visualization