GeneInfo:
| GeneAttribute |
GeneDescription |
| GeneSymbol |
GFRA3 |
| FullNmae |
GDNF family receptor alpha 3 |
| LocusType |
gene with protein product |
| Status |
Approved |
| HGNC_id |
HGNC:4245 |
| EnsembleID |
ENSG00000146013 |
| Uniprot |
O60609 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol |
CellDeathType |
PMID |
Description |
GeneType |
| GFRA3 |
cuproptosis |
36353226 |
The cell proliferation assay revealed that the knockdown of BARX1 and聽GFRA3 deficiency facilitated the cuproptosis induced by elesclomol-CuCl2. |
suppressor |
Go Annotation:
| GeneSymbol |
Go id |
| GFRA3 |
GO:0001764,GO:0005102,GO:0005515,GO:0005829,GO:0005886,GO:0005886,GO:0007165,GO:0007399,GO:0007411,GO:0007422,GO:0008046,GO:0009897,GO:0019898,GO:0038023,GO:0043235,GO:0048485 |
Protein-Protein Interaction(String):
Signalink 3.0 modificators
| Source |
Target |
Pmid |
Interactiontype |
Methods |
Database |
| YBX1 |
GFRA3 |
19151767
|
trascriptional regulation,stimulation |
chromatin immunoprecipitation assay |
TFlink |
| PRDM14 |
GFRA3 |
18971253
20953172
|
trascriptional regulation,stimulation |
inferred by curator,chromatin immunoprecipitation assay |
TFlink |
| SMARCA4 |
GFRA3 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
| CEBPA |
GFRA3 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
| E2F1 |
GFRA3 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
| EGR1 |
GFRA3 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
| HNF4A |
GFRA3 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
| MITF |
GFRA3 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
| TAL1 |
GFRA3 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
| Source |
Target |
Pmid |
Interactiontype |
Methods |
Database |
| URS00000EED18 |
GFRA3 |
25416803
28356515
|
mrna cleavage,inhibition |
western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay |
TarBase |
| Source |
Target |
Pmid |
Interactiontype |
Methods |
Database |
| RET |
GFRA3 |
27898060
9883723
|
N/A |
N/A |
OmniPath |
Visualization