Gene Information gene info

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GENE：GLRX5

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol GLRX5
FullNmae glutaredoxin 5
LocusType gene with protein product
Status Approved
HGNC_id HGNC:20134
EnsembleID ENSG00000182512
Uniprot Q86SX6

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
GLRX5 autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
GLRX5 cuproptosis 36313717 The details of ninety-six candidate cuproptosis-related genes involved in the copper homeostasis regulatory pathway, copper metabolism diseases, mitochondrial respiratory, and iron-sulfur cluster proteins were exhibited in聽Table S1. Genes of iron-sulfur cluster related proteins
GLRX5 cuproptosis 36118866 FeS Cluster cuproptosis gene
GLRX5 cuproptosis 36685880 A total of 43 CRGs were manually identified and used to investigate the effects of cuproptosis in HNSC in current study. cuproptosis-related genes
GLRX5 cuproptosis 36505872 A total of 44 cuproptosis-related genes were extracted from known literature. cuproptosis-related genes

Go Annotation:

GeneSymbol Go id
GLRX5 GO:0005515,GO:0005739,GO:0005739,GO:0005739,GO:0005759,GO:0005759,GO:0005759,GO:0006879,GO:0016226,GO:0030097,GO:0030425,GO:0043025,GO:0044571,GO:0045454,GO:0046872,GO:0051537,GO:0106034,GO:0106035,GO:1990229

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
APP GLRX5 21832049 23180781 physical association protein array InnateDB

Source Target Pmid Interactiontype Methods Database
GATA2 GLRX5 18971253 19941826 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
FOXP3 GLRX5 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
PRDM14 GLRX5 18971253 20953172 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 GLRX5 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA GLRX5 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF GLRX5 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 GLRX5 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS GLRX5 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 GLRX5 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A GLRX5 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TRIM28 GLRX5 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000153377 GLRX5 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000035CC3E GLRX5 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00003BBF48 GLRX5 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00000821E0 GLRX5 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS0000008A99 GLRX5 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000000C73C GLRX5 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS0000521626 GLRX5 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00000B0E50 GLRX5 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS0000535FDD GLRX5 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00002233F4 GLRX5 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000075C4B1 GLRX5 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00003538C1 GLRX5 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000041CB9C GLRX5 21572407 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
GLRX5 GLRX5 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
CHCHD2 GLRX5 25348397 N/A physical interaction ComPPI
BOLA1 GLRX5 24234451 25348397 27499296 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
KEAP1 GLRX5 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
NIT1 GLRX5 24234451 25348397 27499296 association anti tag coimmunoprecipitation ComPPI,IntAct
TXN GLRX5 25348397 N/A physical interaction ComPPI
VHL GLRX5 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
PDK1 GLRX5 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
ELAC2 GLRX5 25348397 N/A physical interaction ComPPI
SPATA20 GLRX5 25348397 N/A physical interaction ComPPI
HSPD1 GLRX5 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
ARF1 GLRX5 25348397 N/A physical interaction ComPPI
ATP5F1A GLRX5 25348397 N/A physical interaction ComPPI
NME4 GLRX5 25348397 N/A physical interaction ComPPI
PAICS GLRX5 25348397 N/A physical interaction ComPPI
MGST3 GLRX5 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
COQ9 GLRX5 25348397 N/A physical interaction ComPPI
GLOD4 GLRX5 25348397 N/A physical interaction ComPPI
APP GLRX5 25348397 N/A physical interaction ComPPI
HLA-B GLRX5 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
TRMT61B GLRX5 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
NDUFS3 GLRX5 25348397 N/A physical interaction ComPPI
OCIAD1 GLRX5 24234451 25348397 27499296 association anti tag coimmunoprecipitation ComPPI,IntAct
DHRS4 GLRX5 25348397 N/A physical interaction ComPPI
GLRX5 BOLA3 24234451 25348397 27499296 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
GLRX5 CISD3 25348397 N/A physical interaction ComPPI
GLRX5 SDHAF4 25348397 N/A physical interaction ComPPI
GLRX5 COQ7 25348397 N/A physical interaction ComPPI
GLRX5 CHCHD10 25348397 N/A physical interaction ComPPI
GLRX5 SDHAF3 25348397 N/A physical interaction ComPPI
GLRX5 NMES1 25348397 N/A physical interaction ComPPI
GLRX5 DGLUCY 24234451 25348397 27499296 association anti tag coimmunoprecipitation ComPPI,IntAct
GLRX5 SPRYD4 24234451 25348397 27499296 association anti tag coimmunoprecipitation ComPPI,IntAct
HSCB GLRX5 24234451 24606901 25348397 28380382 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation ComPPI,IntAct

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