Gene Information gene info

  1. Home

GENE：GNL3

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol GNL3
FullNmae G protein nucleolar 3
LocusType gene with protein product
Status Approved
HGNC_id HGNC:29931
EnsembleID ENSG00000163938
Uniprot Q9BVP2

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
GNL3 cuproptosis 36010978 Derived from the genome-wide CRISPR-Cas9 loss-of-function test reported in previous literature, 347 potential cuproptosis-related genes (FDR < 0.05) were identified, and for a detailed list of genes, see聽Supplementary Table S1. Cuproptosis-related genes

Go Annotation:

GeneSymbol Go id
GNL3 GO:0003723,GO:0005515,GO:0005525,GO:0005615,GO:0005634,GO:0005694,GO:0005730,GO:0005730,GO:0005730,GO:0016020,GO:0016604,GO:0017145,GO:0019827,GO:0030496,GO:0032206,GO:0033235,GO:0042127,GO:0048027,GO:1902895,GO:1904816

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
GNL3 hsa:26354 path:hsa03008 Ribosome biogenesis in eukaryotes - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
GNL3 TERF1 18680434 19487455 22045740 26192618 interaction type N/A ACSN
OAS3 GNL3 21903422 23180781 physical association anti tag coimmunoprecipitation InnateDB
EIF2AK2 GNL3 21903422 23180781 physical association anti tag coimmunoprecipitation InnateDB
GNL3 STAT3 21988832 23180781 physical association pull down InnateDB

Source Target Pmid Interactiontype Methods Database
ETS1 GNL3 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
FOXA1 GNL3 18971253 21878914 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
MYC GNL3 12747840 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 GNL3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA GNL3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF GNL3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 GNL3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 GNL3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 GNL3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A GNL3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF GNL3 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS000003ABC4 GNL3 19088304 25416803 mrna cleavage,inhibition array technology TarBase
URS00003D5391 GNL3 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000345DEB GNL3 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00001123BD GNL3 20371350 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS0000285DCB GNL3 20371350 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000005A8ED GNL3 20371350 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00001EFEC1 GNL3 20371350 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00000393C7 GNL3 20371350 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00001481F9 GNL3 20371350 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00002A71AD GNL3 20371350 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00005E1A16 GNL3 20371350 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS0000140295 GNL3 20371350 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000075B538 GNL3 20371350 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS0000284586 GNL3 20371350 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000045B99E GNL3 20371350 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS0000427B68 GNL3 20371350 21572407 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
CIAO1 GNL3 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
RPS7 GNL3 25348397 N/A physical interaction ComPPI
CEP19 GNL3 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
NPM1 GNL3 25348397 N/A physical interaction ComPPI
RPL37A GNL3 25348397 N/A physical interaction ComPPI
CDKN1B GNL3 25348397 N/A physical interaction ComPPI
LMNA GNL3 24234451 25348397 29568061 association pull down ComPPI,IntAct
RPL11 GNL3 25348397 N/A physical interaction ComPPI
KEAP1 GNL3 25348397 N/A physical interaction ComPPI
NIFK GNL3 25348397 N/A physical interaction ComPPI
INO80B GNL3 25348397 N/A physical interaction ComPPI
RRS1 GNL3 25348397 N/A physical interaction ComPPI
RPL10 GNL3 25348397 N/A physical interaction ComPPI
JUN GNL3 24234451 25348397 25609649 association anti bait coimmunoprecipitation ComPPI,IntAct
COPS5 GNL3 25348397 N/A physical interaction ComPPI
RPL18A GNL3 25348397 N/A physical interaction ComPPI
CUL3 GNL3 25348397 N/A physical interaction ComPPI
CDKN2A GNL3 25348397 N/A physical interaction ComPPI
NTRK1 GNL3 25348397 N/A physical interaction ComPPI
CANX GNL3 24234451 25348397 29568061 association pull down ComPPI,IntAct
YBX1 GNL3 24234451 25348397 25497084 association anti bait coimmunoprecipitation ComPPI,IntAct
EIF2AK2 GNL3 21903422 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PPP2R5A GNL3 14525934 16097049 24234451 25348397 27898060 physical association anti bait coimmunoprecipitation,two hybrid,experimental interaction detection,in vivo,two hybrid ComPPI,HPRD,IntAct,OmniPath
MYC GNL3 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
HNRNPU GNL3 25348397 N/A physical interaction ComPPI
HNRNPL GNL3 25348397 N/A physical interaction ComPPI
TERT GNL3 24234451 24550003 25348397 colocalization,association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,fluorescence microscopy ComPPI,IntAct
EIF6 GNL3 25348397 N/A physical interaction ComPPI
PDHA1 GNL3 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
NR2F6 GNL3 20195357 24234451 25348397 physical association display technology ComPPI,IntAct
RAB5A GNL3 24234451 25348397 29568061 association pull down ComPPI,IntAct
BCCIP GNL3 25348397 N/A physical interaction ComPPI
RBBP4 GNL3 25348397 N/A physical interaction ComPPI
RPS6 GNL3 24234451 25348397 29568061 association pull down,physical interaction,proximity-dependent biotin identification ComPPI,IntAct
RPL4 GNL3 25348397 N/A physical interaction ComPPI
SMNDC1 GNL3 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
MDM2 GNL3 21132010 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
CUL1 GNL3 25348397 N/A physical interaction ComPPI
PSTPIP1 GNL3 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
RNF2 GNL3 25348397 N/A physical interaction ComPPI
GABARAP GNL3 20562859 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
GNL3 ASCC2 14525934 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
GNL3 TP53 12464630 14525934 24234451 25348397 physical association anti bait coimmunoprecipitation,experimental interaction detection,physical interaction ComPPI,HPRD,IntAct
GNL3 DOT1L 25348397 N/A physical interaction ComPPI
GNL3 TERF1 17000763 19487455 25348397 27898060 N/A physical interaction ComPPI,OmniPath
GNL3 NOP56 25348397 N/A physical interaction ComPPI
GNL3 OAS3 21903422 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
GNL3 HDGF 21907836 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
GNL3 SIRT7 25348397 N/A physical interaction ComPPI
GNL3 CAND1 25348397 N/A physical interaction ComPPI
GNL3 RPL6 25348397 N/A physical interaction ComPPI
GNL3 RPL7 25348397 N/A physical interaction ComPPI
GNL3 RPL15 25348397 N/A physical interaction ComPPI
GNL3 FBL 24234451 25348397 29568061 association pull down,physical interaction ComPPI,IntAct
GNL3 RPS15A 25348397 N/A physical interaction ComPPI
GNL3 RPL19 25348397 N/A physical interaction ComPPI
GNL3 RPS4X 25348397 N/A physical interaction ComPPI
GNL3 RPS5 25348397 N/A physical interaction ComPPI
GNL3 RPS3 25348397 N/A physical interaction ComPPI
GNL3 RPL5 25348397 N/A physical interaction ComPPI
GNL3 SNU13 25348397 N/A physical interaction ComPPI
GNL3 RPS8 25348397 N/A physical interaction ComPPI
GNL3 RPS24 25348397 N/A physical interaction ComPPI
GNL3 NOP58 25348397 N/A physical interaction ComPPI
GNL3 RNPS1 25348397 N/A physical interaction ComPPI
GNL3 NOP2 25348397 N/A physical interaction ComPPI
GNL3 FTSJ3 25348397 N/A physical interaction ComPPI
GNL3 DIDO1 25348397 N/A physical interaction ComPPI
GNL3 BOP1 25348397 N/A physical interaction ComPPI
GNL3 ESR1 21182205 24234451 25348397 association affinity chromatography technology,cosedimentation through density gradient,physical interaction ComPPI,IntAct
GNL3 MPG 25348397 N/A physical interaction ComPPI
GNL3 STAT3 21988832 24234451 25348397 physical association two hybrid,pull down,physical interaction ComPPI,IntAct
GNL3 SRPK3 23602568 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
GNL3 TARDBP 25348397 N/A physical interaction ComPPI
GNL3 CDKN2A 25348397 N/A physical interaction ComPPI
GNL3 TRIP12 25348397 N/A physical interaction ComPPI
GNL3 CUL7 25348397 N/A physical interaction ComPPI
GNL3 OBSL1 25348397 N/A physical interaction ComPPI
GNL3 EED 25348397 N/A physical interaction ComPPI
GNL3 DDX24 25348397 N/A physical interaction ComPPI
GNL3 DKC1 25348397 N/A physical interaction ComPPI
GNL3 PUM3 25348397 N/A physical interaction ComPPI
GNL3 KRR1 25348397 N/A physical interaction ComPPI
GNL3 PES1 25348397 N/A physical interaction ComPPI
GNL3 RBBP7 25348397 N/A physical interaction ComPPI
GNL3 TEX10 25348397 N/A physical interaction ComPPI
GNL3 IFI16 25348397 N/A physical interaction ComPPI
GNL3 ZNF746 25348397 N/A physical interaction ComPPI
GNL3 RPL18 25348397 N/A physical interaction ComPPI
GNL3 PPAN 25348397 N/A physical interaction ComPPI
GNL3 NCL 25348397 N/A physical interaction ComPPI
GNL3 DLST 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
GNL3 TRIM25 25348397 N/A physical interaction ComPPI
GNL3 MTF1 25348397 N/A physical interaction ComPPI
GNL3 WRAP73 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
GNL3 PHLDA3 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
GNL3 AGO1 17932509 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
GNL3 AGO2 17932509 24234451 24550003 25348397 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation ComPPI,IntAct
GNL3 ESR2 21182203 24234451 25348397 association affinity chromatography technology,cosedimentation through density gradient ComPPI,IntAct
GNL3 CBX6 21282530 24234451 25348397 association tandem affinity purification ComPPI,IntAct
GNL3 DYSF 23414517 24234451 25348397 physical association two hybrid fragment pooling approach ComPPI,IntAct
GNL3 MNDA 24234451 25348397 25665578 association anti tag coimmunoprecipitation ComPPI,IntAct
GNL3 RRP1B 20926688 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
GNL3 TGOLN2 24234451 25348397 29568061 association pull down ComPPI,IntAct
H3C1 GNL3 24234451 25348397 29568061 association pull down ComPPI,IntAct
RPL23 GNL3 25348397 N/A physical interaction ComPPI
AURKAIP1 GNL3 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
RPL14 GNL3 25348397 N/A physical interaction ComPPI
EIF4A3 GNL3 25348397 N/A physical interaction ComPPI
RPS14 GNL3 25348397 N/A physical interaction ComPPI
LYAR GNL3 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
EBNA1BP2 GNL3 25348397 N/A physical interaction ComPPI
RRP7A GNL3 25348397 N/A physical interaction ComPPI
MKI67 GNL3 24234451 26949251 association anti tag coimmunoprecipitation IntAct
METTL3 GNL3 24234451 29507755 association anti tag coimmunoprecipitation IntAct
DDX18 GNL3 24234451 30021884 physical association cross-linking study IntAct
GNL3 TP53 12464630 19033382 20664182 27898060 inhibition,stimulant N/A OmniPath
GNL3 STAT3 21988832 27898060 N/A N/A OmniPath

Visualization










  Return