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GENE：H2AC6

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol H2AC6
FullNmae H2A clustered histone 6
LocusType gene with protein product
Status Approved
HGNC_id HGNC:4733
EnsembleID ENSG00000180573
Uniprot Q93077

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
H2AC6 cuproptosis 36010978 Derived from the genome-wide CRISPR-Cas9 loss-of-function test reported in previous literature, 347 potential cuproptosis-related genes (FDR < 0.05) were identified, and for a detailed list of genes, see聽Supplementary Table S1. Cuproptosis-related genes

Go Annotation:

GeneSymbol Go id
H2AC6 GO:0000786,GO:0003674,GO:0003677,GO:0005515,GO:0005634,GO:0005634,GO:0005654,GO:0008285,GO:0030527,GO:0046982,GO:0070062

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
H2AC6 hsa:8334 path:hsa03082 ATP-dependent chromatin remodeling - Homo sapiens (human)
H2AC6 hsa:8334 path:hsa04217 Necroptosis - Homo sapiens (human)
H2AC6 hsa:8334 path:hsa04613 Neutrophil extracellular trap formation - Homo sapiens (human)
H2AC6 hsa:8334 path:hsa05034 Alcoholism - Homo sapiens (human)
H2AC6 hsa:8334 path:hsa05322 Systemic lupus erythematosus - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
GATA1 H2AC6 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA2 H2AC6 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA3 H2AC6 21878914 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
FOXA1 H2AC6 18971253 21878914 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
FOXP3 H2AC6 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
SMARCA4 H2AC6 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 H2AC6 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 H2AC6 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXP1 H2AC6 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS H2AC6 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00000EED18 H2AC6 21566225 25416803 mrna cleavage,inhibition experimental interaction detection TarBase
URS0000122ED0 H2AC6 19088304 25416803 mrna cleavage,inhibition array technology TarBase
URS00002F3336 H2AC6 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00005CC20C H2AC6 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000007A060 H2AC6 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000170CF4 H2AC6 23622248 25416803 mrna cleavage,inhibition clash TarBase

Source Target Pmid Interactiontype Methods Database
MCM5 H2AC6 25348397 N/A physical interaction ComPPI
MCM2 H2AC6 25348397 N/A physical interaction ComPPI
ITGA4 H2AC6 25348397 N/A physical interaction ComPPI
AIRE H2AC6 25348397 N/A physical interaction ComPPI
MTNR1A H2AC6 24234451 25348397 26514267 physical association ubiquitin reconstruction,physical interaction ComPPI,IntAct
H2AC6 HEMGN 25348397 N/A physical interaction ComPPI

Visualization










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