Gene Information gene info

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GENE：IDH3B

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol IDH3B
FullNmae isocitrate dehydrogenase (NAD(+)) 3 non-catalytic subunit beta
LocusType gene with protein product
Status Approved
HGNC_id HGNC:5385
EnsembleID ENSG00000101365
Uniprot O43837

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
IDH3B cuproptosis 36324575 TCA and copper malnutrition-related genes (CDKN2A, IDH1, OGDHL, IDH3G, IDH3B, GLS, DLAT, LIPT1)聽were finally included. copper malnutrition-related genes

Go Annotation:

GeneSymbol Go id
IDH3B GO:0000287,GO:0004449,GO:0005634,GO:0005739,GO:0005739,GO:0005739,GO:0005759,GO:0005962,GO:0006099,GO:0006099,GO:0006102,GO:0009055,GO:0022900,GO:0051287

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
IDH3B hsa:3420 path:hsa00020 Citrate cycle (TCA cycle) - Homo sapiens (human)
IDH3B hsa:3420 path:hsa01100 Metabolic pathways - Homo sapiens (human)
IDH3B hsa:3420 path:hsa01200 Carbon metabolism - Homo sapiens (human)
IDH3B hsa:3420 path:hsa01210 2-Oxocarboxylic acid metabolism - Homo sapiens (human)
IDH3B hsa:3420 path:hsa01230 Biosynthesis of amino acids - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
ADRB2 IDH3B 23180781 23798571 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
ETS1 IDH3B 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
YBX1 IDH3B 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 IDH3B 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF IDH3B 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 IDH3B 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A IDH3B 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF IDH3B 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 IDH3B 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MYC IDH3B N/A trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000302909 IDH3B 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00003D5391 IDH3B 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000148B91 IDH3B 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00000F4AC3 IDH3B 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS000023133F IDH3B 19536157 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
IDH2 IDH3B 25361965 interaction type N/A PTMCode2
IDH3B IDH2 25361965 interaction type N/A PTMCode2
DLST IDH3B 25361965 interaction type N/A PTMCode2
IDH3B DLST 25361965 interaction type N/A PTMCode2
IDH3G IDH3B 25361965 interaction type N/A PTMCode2
IDH3B IDH3G 25361965 interaction type N/A PTMCode2
DLD IDH3B 25361965 interaction type N/A PTMCode2
IDH3B DLD 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
KEAP1 IDH3B 25348397 N/A physical interaction ComPPI
CASP3 IDH3B 25348397 N/A physical interaction ComPPI
JUN IDH3B 24234451 25348397 25609649 association anti bait coimmunoprecipitation ComPPI,IntAct
NTRK1 IDH3B 25348397 N/A physical interaction ComPPI
IDH2 IDH3B 25348397 N/A physical interaction ComPPI
PRMT1 IDH3B 14525934 16169070 24234451 25348397 physical association two hybrid,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
MYC IDH3B 17314511 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
CFTR IDH3B 25348397 N/A physical interaction ComPPI
NPHP1 IDH3B 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
MAPK6 IDH3B 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
NFATC2 IDH3B 25348397 N/A physical interaction ComPPI
ADRB2 IDH3B 25348397 N/A physical interaction ComPPI
EGFR IDH3B 25348397 N/A physical interaction ComPPI
MMS19 IDH3B 25348397 N/A physical interaction ComPPI
ATXN3 IDH3B 25348397 N/A physical interaction ComPPI
IDH3A IDH3B 10601238 14525934 25348397 N/A experimental interaction detection,physical interaction,ion exchange chromatography,in vitro,in vivo ComPPI,HPRD
IDH3G IDH3B 10677231 14525934 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
IDH3B ATXN2 14525934 16713569 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array,two hybrid ComPPI,HPRD,IntAct
IDH3B RAB35 14525934 16169070 24234451 25348397 physical association two hybrid,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
IDH3B TP53 25348397 N/A physical interaction ComPPI
IDH3B MOV10 25348397 N/A physical interaction ComPPI
IDH3B NXF1 25348397 N/A physical interaction ComPPI
IDH3B CUL7 25348397 N/A physical interaction ComPPI
IDH3B DBT 25348397 N/A physical interaction ComPPI
IDH3B GDF3 25348397 N/A physical interaction ComPPI
IDH3B IDH1 25348397 N/A physical interaction ComPPI
IDH3B OFD1 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
IDH3B PCM1 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
IDH3B TCTN3 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
IDH3B CEP164 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
IDH3B CNTRL 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
IDH3B RPGRIP1L 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
IDH3B POC5 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
IDH3B OTUB1 24234451 25348397 26752685 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
IDH3B GPD1 25348397 N/A physical interaction ComPPI
IDH3B PHLDA3 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
IDH3B CLPP 24234451 25348397 26058080 association proximity-dependent biotin identification ComPPI,IntAct
IDH3B HSPD1 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
IDH3B PDK1 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
TRMT61B IDH3B 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
HSCB IDH3B 24234451 25348397 28380382 association anti bait coimmunoprecipitation ComPPI,IntAct

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