Gene Information gene info

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GENE：IFT81

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol IFT81
FullNmae intraflagellar transport 81
LocusType gene with protein product
Status Approved
HGNC_id HGNC:14313
EnsembleID ENSG00000122970
Uniprot Q8WYA0

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
IFT81 cuproptosis 36010978 Derived from the genome-wide CRISPR-Cas9 loss-of-function test reported in previous literature, 347 potential cuproptosis-related genes (FDR < 0.05) were identified, and for a detailed list of genes, see聽Supplementary Table S1. Cuproptosis-related genes

Go Annotation:

GeneSymbol Go id
IFT81 GO:0005515,GO:0005737,GO:0005813,GO:0005814,GO:0005929,GO:0005929,GO:0005929,GO:0007283,GO:0008589,GO:0015631,GO:0015631,GO:0030992,GO:0030992,GO:0030992,GO:0031514,GO:0035720,GO:0035735,GO:0036064,GO:0042073,GO:0060271,GO:0060271,GO:0097225,GO:0097228,GO:0097542,GO:0120316

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
GATA2 IFT81 18971253 19941826 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 IFT81 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA IFT81 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF IFT81 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 IFT81 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 IFT81 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 IFT81 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS IFT81 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A IFT81 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF IFT81 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000237AF9 IFT81 18185580 25416803 mrna cleavage,inhibition array technology TarBase

Source Target Pmid Interactiontype Methods Database
NDC80 IFT81 25348397 N/A physical interaction ComPPI
GLI1 IFT81 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
RHPN1 IFT81 25348397 N/A physical interaction ComPPI
NTRK1 IFT81 25348397 N/A physical interaction ComPPI
ODF2 IFT81 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
LTBR IFT81 25348397 N/A physical interaction ComPPI
IFT57 IFT81 25348397 N/A physical interaction ComPPI
IFT20 IFT81 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
MED4 IFT81 25348397 N/A physical interaction ComPPI
NINL IFT81 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
CEP44 IFT81 25348397 N/A physical interaction ComPPI
CEP63 IFT81 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
FGF8 IFT81 25348397 N/A physical interaction ComPPI
OFD1 IFT81 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
APP IFT81 25348397 N/A physical interaction ComPPI
PCM1 IFT81 24234451 25348397 26638075 association anti tag coimmunoprecipitation,physical interaction,proximity-dependent biotin identification ComPPI,IntAct
FBF1 IFT81 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
UBXN10 IFT81 25348397 N/A physical interaction ComPPI
IFT81 CCDC28B 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
IFT81 PPP2CB 24234451 30021884 physical association cross-linking study IntAct

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