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GENE：IMP4

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol IMP4
FullNmae IMP U3 small nucleolar ribonucleoprotein 4
LocusType gene with protein product
Status Approved
HGNC_id HGNC:30856
EnsembleID ENSG00000136718
Uniprot Q96G21

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
IMP4 cuproptosis 36010978 Derived from the genome-wide CRISPR-Cas9 loss-of-function test reported in previous literature, 347 potential cuproptosis-related genes (FDR < 0.05) were identified, and for a detailed list of genes, see聽Supplementary Table S1. Cuproptosis-related genes

Go Annotation:

GeneSymbol Go id
IMP4 GO:0001650,GO:0005515,GO:0005654,GO:0005730,GO:0005730,GO:0005730,GO:0006364,GO:0006364,GO:0030490,GO:0030515,GO:0030684,GO:0032040,GO:0032040,GO:0034457,GO:0034457,GO:0034457,GO:0042134,GO:0042274

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
IMP4 hsa:92856 path:hsa03008 Ribosome biogenesis in eukaryotes - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
APP IMP4 21832049 23180781 physical association protein array InnateDB

Source Target Pmid Interactiontype Methods Database
AR IMP4 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 IMP4 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA2 IMP4 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 IMP4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF IMP4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 IMP4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS IMP4 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000122ED0 IMP4 19088304 25416803 mrna cleavage,inhibition array technology TarBase
URS00003CF1AD IMP4 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000759B6A IMP4 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00001FC26E IMP4 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00005CCD18 IMP4 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000486E0B IMP4 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000034E58D IMP4 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000013ABA3 IMP4 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000075AB0E IMP4 23824327 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000075AB14 IMP4 23824327 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00000EE7F0 IMP4 23824327 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000030F801 IMP4 23824327 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00000011DF IMP4 23824327 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000046CDA6 IMP4 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00005E6F45 IMP4 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS00002FF522 IMP4 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS0000366551 IMP4 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS0000170CF4 IMP4 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000007F792 IMP4 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00000AD002 IMP4 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS0000078918 IMP4 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00004CCA62 IMP4 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000039A052 IMP4 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000021202F IMP4 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS0000076E54 IMP4 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000075C4B1 IMP4 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000075CC78 IMP4 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00002B0B46 IMP4 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS0000259AE4 IMP4 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000075D814 IMP4 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000075D15B IMP4 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00001012BC IMP4 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000045147B IMP4 25416803 27292025 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
IMP4 NOP58 25361965 interaction type N/A PTMCode2
NOP58 IMP4 25361965 interaction type N/A PTMCode2
IMP4 PWP2 25361965 interaction type N/A PTMCode2
PWP2 IMP4 25361965 interaction type N/A PTMCode2
IMP4 UTP15 25361965 interaction type N/A PTMCode2
UTP15 IMP4 25361965 interaction type N/A PTMCode2
IMP4 IMP3 25361965 interaction type N/A PTMCode2
IMP3 IMP4 25361965 interaction type N/A PTMCode2
IMP4 NOC4L 25361965 interaction type N/A PTMCode2
NOC4L IMP4 25361965 interaction type N/A PTMCode2
IMP4 BMS1 25361965 interaction type N/A PTMCode2
BMS1 IMP4 25361965 interaction type N/A PTMCode2
MPHOSPH10 IMP4 25361965 interaction type N/A PTMCode2
IMP4 MPHOSPH10 25361965 interaction type N/A PTMCode2
FBL IMP4 25361965 interaction type N/A PTMCode2
IMP4 FBL 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
IMP4 MPHOSPH10 10409734 12655004 14525934 14990745 25348397 26344197 27898060 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD,OmniPath
IMP4 APP 25348397 N/A physical interaction ComPPI
IMP4 ZBTB7B 21516116 24234451 25348397 25416956 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
IMP4 ILF2 25348397 N/A physical interaction ComPPI
IMP4 DDX52 25348397 N/A physical interaction ComPPI
IMP4 UTP3 25348397 N/A physical interaction ComPPI
IMP4 NAT10 25348397 N/A physical interaction ComPPI
IMP4 NOL10 25348397 N/A physical interaction ComPPI
IMP4 IFI16 25348397 N/A physical interaction ComPPI
IMP4 S100B 25348397 N/A physical interaction ComPPI
IMP4 PCNT 25348397 N/A physical interaction ComPPI
IMP4 RPL10 25348397 N/A physical interaction ComPPI
IMP4 THOC5 25348397 N/A physical interaction ComPPI
IMP4 NOP56 25348397 N/A physical interaction ComPPI
IMP4 MCM2 25348397 N/A physical interaction ComPPI
IMP4 ZNF692 25348397 N/A physical interaction ComPPI
IMP4 ZNF2 25348397 N/A physical interaction ComPPI
IMP4 WDR46 25348397 N/A physical interaction ComPPI
IMP4 RPL30 25348397 N/A physical interaction ComPPI
IMP4 RPL37A 25348397 N/A physical interaction ComPPI
IMP4 RBM34 25348397 N/A physical interaction ComPPI
IMP4 RPL18A 25348397 N/A physical interaction ComPPI
IMP4 NOP53 25348397 N/A physical interaction ComPPI
IMP4 RRP1B 20926688 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
IMP4 RPS6 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
IMP4 FBL 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
LTB4R2 IMP4 24234451 28298427 physical association ubiquitin reconstruction IntAct
IMP4 IMP3 19482034 27898060 N/A N/A OmniPath

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