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GENE：KIDINS220

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol KIDINS220
FullNmae kinase D interacting substrate 220
LocusType gene with protein product
Status Approved
HGNC_id HGNC:29508
EnsembleID ENSG00000134313
Uniprot Q9ULH0

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
KIDINS220 cuproptosis 36010978 Derived from the genome-wide CRISPR-Cas9 loss-of-function test reported in previous literature, 347 potential cuproptosis-related genes (FDR < 0.05) were identified, and for a detailed list of genes, see聽Supplementary Table S1. Cuproptosis-related genes

Go Annotation:

GeneSymbol Go id
KIDINS220 GO:0001701,GO:0005770,GO:0005829,GO:0010976,GO:0016020,GO:0019887,GO:0030165,GO:0030165,GO:0032991,GO:0038180,GO:0038180,GO:0048813,GO:1990090

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
KIDINS220 hsa:57498 path:hsa04722 Neurotrophin signaling pathway - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
KIDINS220 NTRK1 20005715 interaction type N/A PSP
KIDINS220 NGFR 20005715 interaction type N/A PSP
KIDINS220 CRKL 20005715 interaction type N/A PSP
KIDINS220 PRKD1 20005715 interaction type N/A PSP
KIDINS220 NTRK3 20005715 interaction type N/A PSP
KIDINS220 NTRK2 20005715 interaction type N/A PSP
KIDINS220 CRKL 15167895 18988627 20005715 N/A N/A SignaLink
KIDINS220 NTRK3 15167895 18988627 20005715 N/A N/A SignaLink
KIDINS220 NTRK1 11150334 15167895 18988627 20005715 20005715 N/A N/A SignaLink
KIDINS220 NTRK2 15167895 18988627 20005715 20005715 N/A N/A SignaLink
KIDINS220 PRKD1 20005715 20005715 N/A N/A SignaLink

Source Target Pmid Interactiontype Methods Database
AR KIDINS220 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
GATA1 KIDINS220 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA2 KIDINS220 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
YBX1 KIDINS220 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 KIDINS220 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA KIDINS220 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF KIDINS220 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 KIDINS220 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 KIDINS220 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS KIDINS220 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A KIDINS220 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00000B59A2 KIDINS220 16822819 25416803 mrna cleavage,inhibition array technology TarBase
URS0000065D58 KIDINS220 18668040 25416803 mrna cleavage,inhibition experimental interaction detection TarBase
URS0000324096 KIDINS220 18668040 25416803 mrna cleavage,inhibition experimental interaction detection TarBase
URS00000BE495 KIDINS220 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000005CE28 KIDINS220 25416803 27329728 mrna cleavage,inhibition western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase

Source Target Pmid Interactiontype Methods Database
CDC73 KIDINS220 14525934 16169070 24234451 25348397 physical association two hybrid,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
KIF5B KIDINS220 25348397 N/A physical interaction ComPPI
CRKL KIDINS220 14525934 15167895 25348397 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
PRKD1 KIDINS220 10998417 14525934 25348397 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
FGFR2 KIDINS220 25348397 N/A physical interaction ComPPI
VAPA KIDINS220 25348397 N/A physical interaction ComPPI
GSK3B KIDINS220 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
RAB7A KIDINS220 25348397 N/A physical interaction ComPPI
NTRK1 KIDINS220 11150334 14525934 15167895 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
CDH1 KIDINS220 25348397 N/A physical interaction ComPPI
CDH5 KIDINS220 25348397 N/A physical interaction ComPPI
PTPN1 KIDINS220 25348397 N/A physical interaction ComPPI
MYC KIDINS220 20195357 24234451 25348397 physical association display technology,physical interaction ComPPI,IntAct
TNFRSF1A KIDINS220 25348397 N/A physical interaction ComPPI
NTRK2 KIDINS220 14525934 15167895 25348397 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
HNRNPL KIDINS220 25348397 N/A physical interaction ComPPI
PDHA1 KIDINS220 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
ATP6AP2 KIDINS220 25348397 N/A physical interaction ComPPI
CLTC KIDINS220 25348397 N/A physical interaction ComPPI
RAB11A KIDINS220 25348397 N/A physical interaction ComPPI
NGFR KIDINS220 11150334 14525934 15378608 25348397 27898060 N/A two hybrid,experimental interaction detection,in vivo,two hybrid ComPPI,HPRD,OmniPath
KIDINS220 MOB4 14525934 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
KIDINS220 FN1 19738201 24234451 25348397 association cross-linking study,physical interaction ComPPI,IntAct
KIDINS220 LGR4 25348397 N/A physical interaction ComPPI
KIDINS220 HLA-DPA1 25348397 N/A physical interaction ComPPI
KIDINS220 CEACAM21 25348397 N/A physical interaction ComPPI
KIDINS220 CGRRF1 25348397 N/A physical interaction ComPPI
KIDINS220 TXNDC15 25348397 N/A physical interaction ComPPI
KIDINS220 VSIG4 25348397 N/A physical interaction ComPPI
KIDINS220 EVA1C 25348397 N/A physical interaction ComPPI
KIDINS220 FAF2 25348397 N/A physical interaction ComPPI
KIDINS220 LDLRAD4 25348397 N/A physical interaction ComPPI
KIDINS220 TMEM17 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
KIDINS220 GAK 25348397 N/A physical interaction ComPPI
KIDINS220 RAB5C 25348397 N/A physical interaction ComPPI
KIDINS220 MYEF2 25348397 N/A physical interaction ComPPI
KIDINS220 GOLT1B 25348397 N/A physical interaction ComPPI
KIDINS220 GTSE1 25348397 N/A physical interaction ComPPI
KIDINS220 XPR1 25348397 N/A physical interaction ComPPI
KIDINS220 VSIG1 25348397 N/A physical interaction ComPPI
KIDINS220 MRAP2 25348397 N/A physical interaction ComPPI
KIDINS220 B4GAT1 25348397 N/A physical interaction ComPPI
KIDINS220 CLMP 25348397 N/A physical interaction ComPPI
KIDINS220 MAGEE1 25348397 N/A physical interaction ComPPI
KIDINS220 CD79B 25348397 N/A physical interaction ComPPI
KIDINS220 DKKL1 25348397 N/A physical interaction ComPPI
KIDINS220 MANSC1 25348397 N/A physical interaction ComPPI
KIDINS220 VCAM1 22623428 24234451 25348397 association cross-linking study ComPPI,IntAct
KIDINS220 HIF1AN 24234451 25348397 26972000 association anti tag coimmunoprecipitation ComPPI,IntAct
KIDINS220 BET1 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
KIDINS220 LAMP1 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
KIDINS220 TGOLN2 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
KIDINS220 NTRK3 14525934 15167895 N/A experimental interaction detection HPRD
DAG1 KIDINS220 24234451 association cross-linking study IntAct
PRKD1 KIDINS220 10998417 18578522 18669648 20068231 27898060 stimulant N/A OmniPath

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