Gene Information gene info

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GENE：LACTB2

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol LACTB2
FullNmae lactamase beta 2
LocusType gene with protein product
Status Approved
HGNC_id HGNC:18512
EnsembleID ENSG00000147592
Uniprot Q53H82

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
LACTB2 cuproptosis 36550822 Next, 11 hub CAGs(cuproptosis-associated genes), including COPB2, MRPL39, PGK1, PRDX1, PCMT1, MPZL3, LACTB2, HSPH1, DIP2B, DLG3, and NFKBIA, were applied to construct a novel prognostic risk signature for BR. cuproptosis-associated gene

Go Annotation:

GeneSymbol Go id
LACTB2 GO:0003727,GO:0003727,GO:0004521,GO:0004521,GO:0005515,GO:0005759,GO:0005759,GO:0008270

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
SMARCA4 LACTB2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA LACTB2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF LACTB2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 LACTB2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS LACTB2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF LACTB2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 LACTB2 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS000003ABC4 LACTB2 19088304 25416803 mrna cleavage,inhibition array technology TarBase
URS0000324096 LACTB2 23622248 25416803 mrna cleavage,inhibition clash TarBase

Source Target Pmid Interactiontype Methods Database
COIL LACTB2 25348397 N/A physical interaction ComPPI
LACTB2 NUP210 25348397 N/A physical interaction ComPPI
LACTB2 SSU72 25348397 N/A physical interaction ComPPI
LACTB2 UBE2H 25348397 N/A physical interaction ComPPI
LACTB2 TXNL1 25348397 N/A physical interaction ComPPI
LACTB2 NAGK 21988832 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
LACTB2 SIAH1 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
LACTB2 OGA 25348397 N/A physical interaction ComPPI
LACTB2 GPI 25348397 N/A physical interaction ComPPI
LACTB2 SOD1 25348397 N/A physical interaction ComPPI
LACTB2 WDR1 25348397 N/A physical interaction ComPPI
LACTB2 PDCD6IP 25348397 N/A physical interaction ComPPI

Source Target Pmid Interactiontype Methods Database
URS00009BE8F5 LACTB2 27087310 direct interaction,inhibition N/A NPInter

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