Gene Information gene info

  1. Home

GENE：LIPT2

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol LIPT2
FullNmae lipoyl(octanoyl) transferase 2
LocusType gene with protein product
Status Approved
HGNC_id HGNC:37216
EnsembleID ENSG00000175536
Uniprot A6NK58

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
LIPT2 cuproptosis 38348451 Lipid metabolism genes. Changes in lipid metabolism can impact cell survival and may contribute to cell death processes. CRGs in the cuproptosis pathway
LIPT2 cuproptosis 36313717 The details of ninety-six candidate cuproptosis-related genes involved in the copper homeostasis regulatory pathway, copper metabolism diseases, mitochondrial respiratory, and iron-sulfur cluster proteins were exhibited in聽Table S1. Cuproptosis genes related mitochondrial respiration
LIPT2 cuproptosis 36353226 Given that cuproptosis is triggered by lipoylated TCA cycle proteins, the protein lipoylation-related genes (GCSH,聽LIAS,聽LIPT1,聽LIPT2,聽NDUFAB1, and聽NNAT) among the different risk groups were analyzed. driver
LIPT2 cuproptosis 36010978 Derived from the genome-wide CRISPR-Cas9 loss-of-function test reported in previous literature, 347 potential cuproptosis-related genes (FDR < 0.05) were identified, and for a detailed list of genes, see聽Supplementary Table S1. Cuproptosis-related genes
LIPT2 cuproptosis 36523779 LIPT2聽and聽NNAT, two other genes involved in lipoylation, may be unidentified marker gene for Cuproptosis. marker

Go Annotation:

GeneSymbol Go id
LIPT2 GO:0005739,GO:0005739,GO:0005759,GO:0009249,GO:0009249,GO:0016874,GO:0019752,GO:0033819,GO:0033819,GO:2000376

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
LIPT2 hsa:387787 path:hsa00785 Lipoic acid metabolism - Homo sapiens (human)
LIPT2 hsa:387787 path:hsa01100 Metabolic pathways - Homo sapiens (human)
LIPT2 hsa:387787 path:hsa01240 Biosynthesis of cofactors - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
SMARCA4 LIPT2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA LIPT2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF LIPT2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ETS1 LIPT2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS LIPT2 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Visualization










  Return