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GENE：LONP1

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol LONP1
FullNmae lon peptidase 1, mitochondrial
LocusType gene with protein product
Status Approved
HGNC_id HGNC:9479
EnsembleID ENSG00000196365
Uniprot P36776

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
LONP1 mitotic_cd 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
LONP1 ferroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
LONP1 autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
LONP1 cuproptosis 36010978 Derived from the genome-wide CRISPR-Cas9 loss-of-function test reported in previous literature, 347 potential cuproptosis-related genes (FDR < 0.05) were identified, and for a detailed list of genes, see聽Supplementary Table S1. Cuproptosis-related genes

Go Annotation:

GeneSymbol Go id
LONP1 GO:0000002,GO:0001666,GO:0003697,GO:0003727,GO:0004176,GO:0004176,GO:0004176,GO:0004252,GO:0005515,GO:0005524,GO:0005654,GO:0005739,GO:0005759,GO:0005759,GO:0005829,GO:0006515,GO:0007005,GO:0007005,GO:0009725,GO:0010044,GO:0016020,GO:0016887,GO:0032042,GO:0034599,GO:0034599,GO:0042645,GO:0042731,GO:0042802,GO:0043531,GO:0043560,GO:0043565,GO:0046627,GO:0050730,GO:0051131,GO:0051603,GO:0051880,GO:0070182,GO:0070407

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
LONP1 COX4I1 12198491 17418790 26192618 interaction type N/A ACSN
LONP1 COX5A 12198491 17418790 26192618 interaction type N/A ACSN
LONP1 COX5B 12198491 17418790 26192618 interaction type N/A ACSN
LONP1 COX6C 12198491 17418790 26192618 interaction type N/A ACSN
LONP1 COX7B 12198491 17418790 26192618 interaction type N/A ACSN
LONP1 COX7C 12198491 17418790 26192618 interaction type N/A ACSN
LONP1 MT-CO1 12198491 17418790 26192618 interaction type N/A ACSN
LONP1 MT-CO2 12198491 17418790 26192618 interaction type N/A ACSN
LONP1 MT-CO3 12198491 17418790 26192618 interaction type N/A ACSN
LONP1 COX4I2 12198491 17418790 26192618 interaction type N/A ACSN
HIF1A LONP1 10102273 10428030 10428780 10435632 10804084 10823814 11557773 11559532 11744734 11756417 11884613 12402042 12676992 12743597 14672622 14684737 14699081 14762718 15024076 15059920 15199147 15240700 15312748 15369676 15379897 15545625 16110315 16126909 16127144 16517405 16517406 16585195 16782875 16888645 17143338 17418790 17533374 17785433 18054315 18056423 18158893 18718909 19211554 20028863 20427344 20535745 20855962 21051947 21765015 22006996 22841746 22850421 22988108 24006507 25043024 25103413 25732824 26192618 7493931 7500013 7508926 8089148 8702901 8955077 9486205 9525945 9707622 interaction type N/A ACSN
LONP1 EGR1 19032775 23180781 physical association anti tag coimmunoprecipitation InnateDB
ADRB2 LONP1 23180781 23798571 physical association anti tag coimmunoprecipitation InnateDB
MAVS LONP1 23180781 25734423 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
ETS1 LONP1 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
HIF1A LONP1 19828020 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
SMARCA4 LONP1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA LONP1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF LONP1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 LONP1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 LONP1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXP1 LONP1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS LONP1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF LONP1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
VDR LONP1 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS000003ABC4 LONP1 19088304 25416803 mrna cleavage,inhibition array technology TarBase
URS0000042E1F LONP1 23622248 25416803 mrna cleavage,inhibition clash TarBase

Source Target Pmid Interactiontype Methods Database
IFIT3 LONP1 21163940 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
KEAP1 LONP1 25348397 N/A physical interaction ComPPI
JUN LONP1 24234451 25348397 25609649 association anti bait coimmunoprecipitation ComPPI,IntAct
SF3B1 LONP1 25348397 N/A physical interaction ComPPI
PSMA3 LONP1 25348397 N/A physical interaction ComPPI
TUBG1 LONP1 24234451 25348397 29568061 association pull down,physical interaction ComPPI,IntAct
NTRK1 LONP1 25348397 N/A physical interaction ComPPI
ILK LONP1 23455922 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
MYC LONP1 17314511 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
APOE LONP1 25348397 N/A physical interaction ComPPI
C1QBP LONP1 25348397 N/A physical interaction ComPPI
DCTN1 LONP1 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
MAPK6 LONP1 24234451 25348397 26972000 association anti tag coimmunoprecipitation ComPPI,IntAct
MTMR11 LONP1 25348397 N/A physical interaction ComPPI
PSMC5 LONP1 25348397 N/A physical interaction ComPPI
CUL1 LONP1 25348397 N/A physical interaction ComPPI
SOX2 LONP1 25348397 N/A physical interaction ComPPI
ADRB2 LONP1 25348397 N/A physical interaction ComPPI
EGFR LONP1 25348397 N/A physical interaction ComPPI
PSMC4 LONP1 25348397 N/A physical interaction ComPPI
VCAM1 LONP1 22623428 24234451 25348397 association cross-linking study ComPPI,IntAct
ITGA4 LONP1 25348397 N/A physical interaction ComPPI
MME LONP1 17342744 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
CUL7 LONP1 25348397 N/A physical interaction ComPPI
LRPPRC LONP1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PDK1 LONP1 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
CDC37 LONP1 21163940 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
MAST1 LONP1 21163940 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
DYNC1H1 LONP1 25348397 N/A physical interaction ComPPI
TRIM25 LONP1 25348397 N/A physical interaction ComPPI
ECSIT LONP1 21163940 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
CLPX LONP1 25348397 N/A physical interaction ComPPI
ESR2 LONP1 21182203 24234451 25348397 association affinity chromatography technology ComPPI,IntAct
UPF3A LONP1 25348397 N/A physical interaction ComPPI
MAP3K3 LONP1 14743216 24234451 25348397 physical association tandem affinity purification ComPPI,IntAct
NDUFS7 LONP1 24234451 24344204 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
AURKAIP1 LONP1 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
CNTRL LONP1 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
CEP162 LONP1 24234451 25348397 26638075 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
TSC22D1 LONP1 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
HSPD1 LONP1 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
LATS2 LONP1 25348397 N/A physical interaction ComPPI
A2M LONP1 21163940 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
USP2 LONP1 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
LOXL4 LONP1 21163940 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
NEU4 LONP1 25348397 N/A physical interaction ComPPI
MRPL4 LONP1 25348397 N/A physical interaction ComPPI
MGST3 LONP1 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
OFD1 LONP1 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
SIRT7 LONP1 25348397 N/A physical interaction ComPPI
RNF32 LONP1 21163940 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
IFIT5 LONP1 21163940 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
SMRP1 LONP1 25348397 N/A physical interaction ComPPI
MKLN1 LONP1 24234451 25348397 27173435 association,physical association physical interaction,tandem affinity purification,inference by socio-affinity scoring ComPPI,IntAct
MRPS24 LONP1 25348397 N/A physical interaction ComPPI
NIPSNAP2 LONP1 25348397 N/A physical interaction ComPPI
LONP1 ATG101 20562859 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
LONP1 MRPL58 20186120 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
LONP1 CYP2C8 21163940 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
LONP1 STPG3 25348397 N/A physical interaction ComPPI
LONP1 TATDN1 25348397 N/A physical interaction ComPPI
LONP1 CEP164 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
LONP1 RPGRIP1L 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
LONP1 ATL3 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
LONP1 KLHDC8A 25348397 N/A physical interaction ComPPI
LONP1 TEX45 25348397 N/A physical interaction ComPPI
LONP1 RASL10B 25348397 N/A physical interaction ComPPI
LONP1 DCAF12L2 25348397 N/A physical interaction ComPPI
LONP1 DCAF4 25348397 N/A physical interaction ComPPI
LONP1 FOXRED1 25348397 N/A physical interaction ComPPI
LONP1 SIRT4 24234451 25348397 25525879 association anti tag coimmunoprecipitation ComPPI,IntAct
LONP1 COQ2 24234451 25348397 29128334 association cross-linking study ComPPI,IntAct
TRMT61B LONP1 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
GCAT LONP1 25348397 N/A physical interaction ComPPI
LONP1 LONP1 24234451 24520911 N/A cross-linking study IntAct
MKI67 LONP1 24234451 26949251 association anti tag coimmunoprecipitation IntAct
SMARCB1 LONP1 24234451 30108113 association proximity-dependent biotin identification IntAct
STK38L LONP1 24234451 30108113 association proximity-dependent biotin identification IntAct

Visualization










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