GENE:MAL2
GeneInfo:
GeneAttribute | GeneDescription |
---|---|
GeneSymbol | MAL2 |
FullNmae | mal, T cell differentiation protein 2 |
LocusType | gene with protein product |
Status | Approved |
HGNC_id | HGNC:13634 |
EnsembleID | ENSG00000147676 |
Uniprot | Q969L2 |
Protein Structure:
Gene Description in Publicaton:
GeneSymbol | CellDeathType | PMID | Description | GeneType |
---|---|---|---|---|
MAL2 | cuproptosis | 36341328 | Further, differentially expressed genes with prognostic significance were used to construct a cuproptosis-related gene signature (PGK1, SLC52A2, SEC14L2, RAD23B, SLC16A6, CCL5, and MAL2) and scoring system. | cuproptosis-related gene signature |
Go Annotation:
GeneSymbol | Go id |
---|---|
MAL2 | GO:0005515,GO:0016324,GO:0019911,GO:0030672,GO:0042552,GO:0045121,GO:0048471,GO:0070062,GO:0098686,GO:0098978 |
Protein-Protein Interaction(String):
Signalink 3.0 modificators
Source | Target | Pmid | Interactiontype | Methods | Database |
---|---|---|---|---|---|
ESR1 | MAL2 | 21878914 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
GATA3 | MAL2 | 21878914 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
FOXA1 | MAL2 | 18971253 21878914 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
TFAP2C | MAL2 | 20629094 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
SMARCA4 | MAL2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
CEBPA | MAL2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
CTCF | MAL2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
E2F1 | MAL2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
HNF4A | MAL2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
Source | Target | Pmid | Interactiontype | Methods | Database |
---|---|---|---|---|---|
URS0000237AF9 | MAL2 | 18185580 25416803 | mrna cleavage,inhibition | array technology | TarBase |
URS00005D986D | MAL2 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00000ED600 | MAL2 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS0000285DCB | MAL2 | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
Source | Target | Pmid | Interactiontype | Methods | Database |
---|---|---|---|---|---|
SH3GLB1 | MAL2 | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
TUBB | MAL2 | 25348397 | N/A | two hybrid,physical interaction | ComPPI |
MAL2 | TPD52L1 | 11549320 14525934 25348397 | N/A | two hybrid,experimental interaction detection,physical interaction,in vitro,two hybrid | ComPPI,HPRD |
MAL2 | PPP1CA | 22321011 24234451 25348397 | physical association | two hybrid,physical interaction | ComPPI,IntAct |
MAL2 | ELAVL1 | 25348397 | N/A | physical interaction | ComPPI |
MAL2 | PBX3 | 25348397 | N/A | physical interaction | ComPPI |
MAL2 | SH3GL1 | 24234451 25348397 | physical association | two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
MAL2 | ARFIP2 | 24234451 25348397 25416956 | physical association | physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid | ComPPI,IntAct |
MAL2 | CREB3 | 25348397 | N/A | physical interaction | ComPPI |
MAL2 | SHMT2 | 24234451 25348397 26871637 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach,validated two hybrid | ComPPI,IntAct |
MAL2 | PIMREG | 24234451 25348397 26871637 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach,validated two hybrid | ComPPI,IntAct |
MAL2 | GAD1 | 24234451 25348397 26871637 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach,validated two hybrid | ComPPI,IntAct |
MAL2 | GJB1 | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
MAL2 | CD68 | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
MAL2 | SGK1 | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
MAL2 | COQ8A | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
MAL2 | TTPA | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
MAL2 | MRM1 | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
MAL2 | CREB3L1 | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
PTPN9 | MAL2 | 24234451 25348397 25416956 | physical association | two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid | ComPPI,IntAct |
Source | Target | Pmid | Interactiontype | Methods | Database |
---|---|---|---|---|---|
URS00009AE7BC | MAL2 | 27087310 | direct interaction,inhibition | N/A | NPInter |