Gene Information gene info

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GENE：MCAT

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol MCAT
FullNmae malonyl-CoA-acyl carrier protein transacylase
LocusType gene with protein product
Status Approved
HGNC_id HGNC:29622
EnsembleID ENSG00000100294
Uniprot Q8IVS2

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
MCAT autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
MCAT cuproptosis 36010978 Derived from the genome-wide CRISPR-Cas9 loss-of-function test reported in previous literature, 347 potential cuproptosis-related genes (FDR < 0.05) were identified, and for a detailed list of genes, see聽Supplementary Table S1. Cuproptosis-related genes

Go Annotation:

GeneSymbol Go id
MCAT GO:0003723,GO:0004314,GO:0004314,GO:0004314,GO:0005739,GO:0005739,GO:0005759,GO:0006633,GO:0006633,GO:0006633,GO:0006635

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
MCAT hsa:27349 path:hsa00061 Fatty acid biosynthesis - Homo sapiens (human)
MCAT hsa:27349 path:hsa01100 Metabolic pathways - Homo sapiens (human)
MCAT hsa:27349 path:hsa01212 Fatty acid metabolism - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
GATA3 MCAT 21878914 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 MCAT 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF MCAT 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 MCAT 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MYT1 MCAT 15378601 trascriptional regulation,stimulation inferred by curator TFlink
MTF1 MCAT 15378601 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000122ED0 MCAT 19088304 25416803 mrna cleavage,inhibition array technology TarBase
URS0000324096 MCAT 18668040 25416803 mrna cleavage,inhibition experimental interaction detection TarBase
URS00003380CC MCAT 25416803 27855320 mrna cleavage,inhibition nucleotide sequence identification,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase

Source Target Pmid Interactiontype Methods Database
RBM3 MCAT 25348397 N/A physical interaction ComPPI
ITGAV MCAT 25348397 N/A physical interaction ComPPI
TAP1 MCAT 25348397 N/A physical interaction ComPPI
PTPN1 MCAT 25348397 N/A physical interaction ComPPI
MYC MCAT 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
SPTAN1 MCAT 25348397 N/A physical interaction ComPPI
EWSR1 MCAT 25348397 N/A physical interaction ComPPI
RXRB MCAT 25348397 N/A physical interaction ComPPI
SUMO3 MCAT 17000644 24234451 25348397 association affinity chromatography technology ComPPI,IntAct
USF1 MCAT 25348397 N/A physical interaction ComPPI
TAF5 MCAT 25348397 N/A physical interaction ComPPI
RAVER1 MCAT 25348397 N/A physical interaction ComPPI
RBMX MCAT 25348397 N/A physical interaction ComPPI
TFEB MCAT 25348397 N/A physical interaction ComPPI
MRPS34 MCAT 25348397 N/A physical interaction ComPPI
HNRNPA1 MCAT 25348397 N/A physical interaction ComPPI
MRPL4 MCAT 25348397 N/A physical interaction ComPPI
ALAS1 MCAT 25348397 N/A physical interaction ComPPI
HNRNPDL MCAT 25348397 N/A physical interaction ComPPI
ZYG11B MCAT 25348397 N/A physical interaction ComPPI
ERAL1 MCAT 25348397 N/A physical interaction ComPPI
MCAT MRPS16 25348397 N/A physical interaction ComPPI
MCAT RPUSD2 25348397 N/A physical interaction ComPPI
MCAT MRPS11 25348397 N/A physical interaction ComPPI

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