Gene Information gene info

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GENE：TUFM

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol TUFM
FullNmae Tu translation elongation factor, mitochondrial
LocusType gene with protein product
Status Approved
HGNC_id HGNC:12420
EnsembleID ENSG00000178952
Uniprot P49411

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
TUFM necroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
TUFM GO:0003723,GO:0003746,GO:0003746,GO:0003924,GO:0005515,GO:0005525,GO:0005739,GO:0005739,GO:0005739,GO:0005741,GO:0006414,GO:0016020,GO:0042645,GO:0045202,GO:0045471,GO:0070062,GO:0070125

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
NDUFAF1 TUFM 17344420 23180781 physical association tandem affinity purification InnateDB
TUFM NLRX1 22749352 23180781 physical association anti tag coimmunoprecipitation InnateDB
TUFM ATG16L1 22749352 23180781 physical association anti tag coimmunoprecipitation InnateDB
CDK2 TUFM 21319273 23180781 physical association anti tag coimmunoprecipitation InnateDB
SUZ12 TUFM 23180781 24457600 physical association anti tag coimmunoprecipitation InnateDB
RNF2 TUFM 23180781 24457600 physical association anti tag coimmunoprecipitation InnateDB
ADRB2 TUFM 23180781 23798571 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
ETS1 TUFM 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
CTCF TUFM 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 TUFM 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 TUFM 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00003D5391 TUFM 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000003FD55 TUFM 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000005481D TUFM 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000021D7C8 TUFM 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00001799A3 TUFM 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000239117 TUFM 23622248 25416803 mrna cleavage,inhibition clash TarBase

Source Target Pmid Interactiontype Methods Database
MRPS2 TUFM 25361965 interaction type N/A PTMCode2
TUFM MRPS2 25361965 interaction type N/A PTMCode2
RPS16 TUFM 25361965 interaction type N/A PTMCode2
TUFM RPS16 25361965 interaction type N/A PTMCode2
RPL8 TUFM 25361965 interaction type N/A PTMCode2
TUFM RPL8 25361965 interaction type N/A PTMCode2
RPS5 TUFM 25361965 interaction type N/A PTMCode2
TUFM RPS5 25361965 interaction type N/A PTMCode2
CLPP TUFM 25361965 interaction type N/A PTMCode2
TUFM CLPP 25361965 interaction type N/A PTMCode2
GFM2 TUFM 25361965 interaction type N/A PTMCode2
TUFM GFM2 25361965 interaction type N/A PTMCode2
MRPL4 TUFM 25361965 interaction type N/A PTMCode2
TUFM MRPL4 25361965 interaction type N/A PTMCode2
RPS14 TUFM 25361965 interaction type N/A PTMCode2
TUFM RPS14 25361965 interaction type N/A PTMCode2
MRPS11 TUFM 25361965 interaction type N/A PTMCode2
TUFM MRPS11 25361965 interaction type N/A PTMCode2
MRPS7 TUFM 25361965 interaction type N/A PTMCode2
TUFM MRPS7 25361965 interaction type N/A PTMCode2
TUFM HSPD1 25361965 interaction type N/A PTMCode2
HSPD1 TUFM 25361965 interaction type N/A PTMCode2
TUFM MRPS16 25361965 interaction type N/A PTMCode2
MRPS16 TUFM 25361965 interaction type N/A PTMCode2
TUFM RPL11 25361965 interaction type N/A PTMCode2
RPL11 TUFM 25361965 interaction type N/A PTMCode2
TUFM MRPL2 25361965 interaction type N/A PTMCode2
MRPL2 TUFM 25361965 interaction type N/A PTMCode2
TUFM TSFM 25361965 interaction type N/A PTMCode2
TSFM TUFM 25361965 interaction type N/A PTMCode2
TUFM GFM1 25361965 interaction type N/A PTMCode2
GFM1 TUFM 25361965 interaction type N/A PTMCode2
MRPL11 TUFM 25361965 interaction type N/A PTMCode2
TUFM MRPL11 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
SNW1 TUFM 20467437 24234451 25348397 association anti bait coimmunoprecipitation ComPPI,IntAct
CUL5 TUFM 25348397 N/A physical interaction ComPPI
PLAA TUFM 25348397 N/A physical interaction ComPPI
RPN1 TUFM 25348397 N/A physical interaction ComPPI
RPL9 TUFM 25348397 N/A physical interaction ComPPI
NPM1 TUFM 25348397 N/A physical interaction ComPPI
RPL37A TUFM 25348397 N/A physical interaction ComPPI
FASTKD3 TUFM 20869947 24234451 25348397 association tandem affinity purification ComPPI,IntAct
UBL4A TUFM 25348397 N/A physical interaction ComPPI
TRAF6 TUFM 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
GABARAPL2 TUFM 20562859 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
RPL11 TUFM 25348397 N/A physical interaction ComPPI
PPP1R2B TUFM 25348397 N/A physical interaction ComPPI
RPS26 TUFM 25348397 N/A physical interaction ComPPI
FBXO17 TUFM 25348397 N/A physical interaction ComPPI
BMI1 TUFM 25348397 N/A physical interaction ComPPI
KEAP1 TUFM 25348397 N/A physical interaction ComPPI
MCM2 TUFM 25348397 N/A physical interaction ComPPI
MAP1LC3B TUFM 20562859 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
TUFM FUNDC1 24234451 25348397 25416956 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
TUFM ATP6V1A 11741979 14525934 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
TUFM MYH9 12577067 14525934 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
TUFM SGK1 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
TUFM BANF1 25348397 N/A physical interaction ComPPI
TUFM UBC 25348397 N/A physical interaction ComPPI
TUFM PPP2R2B 19156129 24234451 25348397 association anti tag coimmunoprecipitation,pull down,physical interaction ComPPI,IntAct
TUFM MRPL58 20186120 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
TUFM AGO4 19167051 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
TUFM HDAC5 25348397 N/A physical interaction ComPPI
TUFM NOP56 25348397 N/A physical interaction ComPPI
TUFM SIRT7 25348397 N/A physical interaction ComPPI
TUFM CUL3 25348397 N/A physical interaction ComPPI
TUFM CUL4B 25348397 N/A physical interaction ComPPI
TUFM CUL2 25348397 N/A physical interaction ComPPI
TUFM CDK2 25348397 N/A physical interaction ComPPI
TUFM COPS5 25348397 N/A physical interaction ComPPI
TUFM GRK5 25348397 N/A physical interaction ComPPI
TUFM RPL17 25348397 N/A physical interaction ComPPI
TUFM RPL23 25348397 N/A physical interaction ComPPI
TUFM RPL8 25348397 N/A physical interaction ComPPI
TUFM RPS11 25348397 N/A physical interaction ComPPI
TUFM RPS15A 25348397 N/A physical interaction ComPPI
TUFM RPS2 25348397 N/A physical interaction ComPPI
TUFM RPS23 25348397 N/A physical interaction ComPPI
TUFM RPL7 25348397 N/A physical interaction ComPPI
TUFM RPL6 25348397 N/A physical interaction ComPPI
TUFM RPL23A 25348397 N/A physical interaction ComPPI
TUFM RPL19 25348397 N/A physical interaction ComPPI
TUFM RPS24 25348397 N/A physical interaction ComPPI
TUFM RPL12 25348397 N/A physical interaction ComPPI
TUFM RPL15 25348397 N/A physical interaction ComPPI
TUFM RPS6 25348397 N/A physical interaction ComPPI
TUFM RPL32 25348397 N/A physical interaction ComPPI
TUFM RPS16 25348397 N/A physical interaction ComPPI
TUFM RPS8 25348397 N/A physical interaction ComPPI
TUFM RPL3 25348397 N/A physical interaction ComPPI
TUFM RPS13 25348397 N/A physical interaction ComPPI
TUFM RPL31 25348397 N/A physical interaction ComPPI
TUFM RPS3 25348397 N/A physical interaction ComPPI
TUFM RPS20 25348397 N/A physical interaction ComPPI
TUFM RPS5 25348397 N/A physical interaction ComPPI
TUFM MRPS7 25348397 N/A physical interaction ComPPI
TUFM MRPL17 25348397 N/A physical interaction ComPPI
TUFM MRPL11 25348397 N/A physical interaction ComPPI
TUFM MRPL14 25348397 N/A physical interaction ComPPI
TUFM MRPS14 25348397 N/A physical interaction ComPPI
TUFM MRPL22 25348397 N/A physical interaction ComPPI
TUFM MRPL4 25348397 N/A physical interaction ComPPI
TUFM MRPL24 25348397 N/A physical interaction ComPPI
TUFM MRPS5 25348397 N/A physical interaction ComPPI
TUFM MRPL23 25348397 N/A physical interaction ComPPI
TUFM PPT2 25348397 N/A physical interaction ComPPI
TUFM CAVIN3 25348397 N/A physical interaction ComPPI
TUFM MRPS10 25348397 N/A physical interaction ComPPI
TUFM HSP90AA1 25348397 N/A physical interaction ComPPI
TUFM HSP90AA2P 25348397 N/A physical interaction ComPPI
TUFM MRPL2 25348397 N/A physical interaction ComPPI
TUFM PHB2 25348397 N/A physical interaction ComPPI
TUFM SFXN3 25348397 N/A physical interaction ComPPI
TUFM SARS2 25348397 N/A physical interaction ComPPI
TUFM MRPL1 25348397 N/A physical interaction ComPPI
TUFM IARS2 25348397 N/A physical interaction ComPPI
TUFM NENF 25348397 N/A physical interaction ComPPI
TUFM SNCG 25348397 N/A physical interaction ComPPI
TUFM ENG 25348397 N/A physical interaction ComPPI
TUFM AK2 25348397 N/A physical interaction ComPPI
TUFM PC 25348397 N/A physical interaction ComPPI
TUFM SMURF1 25348397 N/A physical interaction ComPPI
TUFM FMNL1 25348397 N/A physical interaction ComPPI
TUFM FN1 25348397 N/A physical interaction ComPPI
TUFM VCAM1 22623428 24234451 25348397 association cross-linking study,physical interaction ComPPI,IntAct
TUFM C1QBP 25348397 N/A physical interaction ComPPI
TUFM ZSWIM7 25348397 N/A physical interaction ComPPI
TUFM PAN2 25348397 N/A physical interaction ComPPI
TUFM CD81 25348397 N/A physical interaction ComPPI
TUFM ADRB2 25348397 N/A physical interaction ComPPI
TUFM EXOSC6 25348397 N/A physical interaction ComPPI
TUFM FBXO6 25348397 N/A physical interaction ComPPI
TUFM PRKN 25348397 N/A physical interaction ComPPI
TUFM DCPS 25348397 N/A physical interaction ComPPI
TUFM GAPDH 25348397 N/A physical interaction ComPPI
TUFM IPO9 25348397 N/A physical interaction ComPPI
TUFM NAE1 25348397 N/A physical interaction ComPPI
TUFM PAFAH1B2 25348397 N/A physical interaction ComPPI
TUFM PPP1R2 25348397 N/A physical interaction ComPPI
TUFM PPP5C 25348397 N/A physical interaction ComPPI
TUFM PLPBP 25348397 N/A physical interaction ComPPI
TUFM TUBB6 25348397 N/A physical interaction ComPPI
TUFM ASL 25348397 N/A physical interaction ComPPI
TUFM CAMK1D 25348397 N/A physical interaction ComPPI
TUFM CAPN2 25348397 N/A physical interaction ComPPI
TUFM CLU 25348397 N/A physical interaction ComPPI
TUFM GTF3C4 25348397 N/A physical interaction ComPPI
TUFM HEXB 25348397 N/A physical interaction ComPPI
TUFM HK1 25348397 N/A physical interaction ComPPI
TUFM NSFL1C 25348397 N/A physical interaction ComPPI
TUFM PDIA4 25348397 N/A physical interaction ComPPI
TUFM TUBB2A 25348397 N/A physical interaction ComPPI
TUFM UBXN1 25348397 N/A physical interaction ComPPI
TUFM XPO1 25348397 N/A physical interaction ComPPI
TUFM ASB10 25348397 N/A physical interaction ComPPI
TUFM ASB12 25348397 N/A physical interaction ComPPI
TUFM MTMR8 25348397 N/A physical interaction ComPPI
TUFM ASB14 25348397 N/A physical interaction ComPPI
TUFM ASB17 25348397 N/A physical interaction ComPPI
TUFM SPRTN 25348397 N/A physical interaction ComPPI
TUFM HUWE1 25348397 N/A physical interaction ComPPI
TUFM FUS 25348397 N/A physical interaction ComPPI
TUFM ARL6IP1 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
TUFM CMTM5 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
TUFM FAM9B 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
TUFM CUL7 25348397 N/A physical interaction ComPPI
TUFM OBSL1 25348397 N/A physical interaction ComPPI
TUFM CCDC8 25348397 N/A physical interaction ComPPI
TUFM SUZ12 25348397 N/A physical interaction ComPPI
TUFM RNF2 25348397 N/A physical interaction ComPPI
TUFM RPS6KB2 25348397 N/A physical interaction ComPPI
TUFM CHMP7 25348397 N/A physical interaction ComPPI
TUFM DDOST 25348397 N/A physical interaction ComPPI
TUFM HIP1R 25348397 N/A physical interaction ComPPI
TUFM ARF1 25348397 N/A physical interaction ComPPI
TUFM CANX 25348397 N/A physical interaction ComPPI
TUFM CLTC 25348397 N/A physical interaction ComPPI
TUFM GFM1 25348397 N/A physical interaction ComPPI
TUFM HNRNPL 25348397 N/A physical interaction ComPPI
TUFM LMAN1 25348397 N/A physical interaction ComPPI
TUFM MRPL18 25348397 N/A physical interaction ComPPI
TUFM MRPL3 25348397 N/A physical interaction ComPPI
TUFM POLR3A 25348397 N/A physical interaction ComPPI
TUFM PTBP1 25348397 N/A physical interaction ComPPI
TUFM RAB5B 25348397 N/A physical interaction ComPPI
TUFM SEPHS1 25348397 N/A physical interaction ComPPI
TUFM SLC25A3 25348397 N/A physical interaction ComPPI
TUFM UQCRC2 25348397 N/A physical interaction ComPPI
TUFM WDR12 25348397 N/A physical interaction ComPPI
TUFM NTRK1 25348397 N/A physical interaction ComPPI
TUFM PTEN 25348397 N/A physical interaction ComPPI
TUFM SKI 25348397 N/A physical interaction ComPPI
TUFM CRY2 25348397 N/A physical interaction ComPPI
TUFM ERBB3 24189400 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
TUFM ESRRB 25348397 N/A physical interaction ComPPI
TUFM U2AF2 25348397 N/A physical interaction ComPPI
TUFM COA3 25348397 N/A physical interaction ComPPI
TUFM NFATC1 25348397 N/A physical interaction ComPPI
TUFM NFATC2 25348397 N/A physical interaction ComPPI
TUFM ATOH1 25348397 N/A physical interaction ComPPI
TUFM AIFM1 24234451 25348397 29568061 association pull down,physical interaction ComPPI,IntAct
TUFM BECN1 25348397 N/A physical interaction ComPPI
TUFM ZNF746 25348397 N/A physical interaction ComPPI
TUFM EGFR 24189400 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
TUFM ZMYM6 25348397 N/A physical interaction ComPPI
TUFM GFM2 25348397 N/A physical interaction ComPPI
TUFM MTIF2 25348397 N/A physical interaction ComPPI
TUFM MCCC1 25348397 N/A physical interaction ComPPI
TUFM GAB1 25348397 N/A physical interaction ComPPI
TUFM PTPRK 25348397 N/A physical interaction ComPPI
TUFM DEFA5 25348397 N/A physical interaction ComPPI
TUFM DKKL1 25348397 N/A physical interaction ComPPI
TUFM PUS1 25348397 N/A physical interaction ComPPI
TUFM ST8SIA4 25348397 N/A physical interaction ComPPI
TUFM MUC20 25348397 N/A physical interaction ComPPI
TUFM CYLD 25348397 N/A physical interaction ComPPI
TUFM G3BP1 25348397 N/A physical interaction ComPPI
TUFM TES 25348397 N/A physical interaction ComPPI
TUFM GRB2 12577067 24234451 25348397 association pull down ComPPI,IntAct
TUFM TNFRSF1B 14743216 24234451 25348397 physical association tandem affinity purification ComPPI,IntAct
TUFM EPB41 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
TUFM EIF6 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
TUFM CCNA1 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
TUFM HLA-C 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
TUFM MCC 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
TUFM HLA-B 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
TUFM TRMT10C 18984158 24234451 25348397 physical association anti tag coimmunoprecipitation ComPPI,IntAct
TUFM MAP1LC3A 20562859 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
TUFM GABARAP 20562859 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
TUFM MYC 21150319 24234451 25348397 association tandem affinity purification ComPPI,IntAct
TUFM ERBB2 24189400 24234451 25348397 association tandem affinity purification ComPPI,IntAct
TUFM PHF19 24234451 25348397 27705803 association tandem affinity purification ComPPI,IntAct
TUFM HTR7 19486527 24234451 25348397 association tandem affinity purification ComPPI,IntAct
TUFM LRRK2 24234451 24725412 25348397 association tandem affinity purification ComPPI,IntAct
TUFM SLC25A5 24234451 24983503 25348397 association anti bait coimmunoprecipitation ComPPI,IntAct
TUFM OTUB1 24234451 25348397 26752685 association anti tag coimmunoprecipitation ComPPI,IntAct
TUFM NFKB1 24234451 25348397 25609649 association tandem affinity purification ComPPI,IntAct
TUFM JUN 24234451 25348397 25609649 association anti bait coimmunoprecipitation ComPPI,IntAct
TUFM SIRT4 24234451 25348397 25525879 association anti tag coimmunoprecipitation ComPPI,IntAct
TUFM NLRX1 24234451 25348397 28611246 association,physical association anti tag coimmunoprecipitation ComPPI,IntAct
TUFM PPEF1 24234451 25348397 28330616 association pull down ComPPI,IntAct
TUFM PLEKHA7 24234451 25348397 28877994 association anti bait coimmunoprecipitation ComPPI,IntAct
TUFM RRP1B 20926688 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
TUFM TUBA1A 24234451 25348397 29568061 association pull down ComPPI,IntAct
RNH1 TUFM 21276451 24234451 25348397 association anti bait coimmunoprecipitation ComPPI,IntAct
CFLAR TUFM 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
RPL14 TUFM 25348397 N/A physical interaction ComPPI
TSSK1B TUFM 25348397 N/A physical interaction ComPPI
METTL3 TUFM 24234451 29507755 association anti tag coimmunoprecipitation IntAct
WTAP TUFM 24234451 29507755 association anti tag coimmunoprecipitation IntAct
METTL14 TUFM 24234451 29507755 association anti tag coimmunoprecipitation IntAct
REV1 TUFM 24234451 30021884 physical association cross-linking study IntAct
TUFM SMC1A 24234451 30021884 physical association cross-linking study IntAct
TUFM POGLUT3 24234451 30021884 physical association cross-linking study IntAct
TUFM SMARCA1 24234451 30021884 physical association cross-linking study IntAct
TUFM ZC2HC1B 24234451 30021884 physical association cross-linking study IntAct
TUFM DUSP3 24234451 30021884 physical association cross-linking study IntAct
TUFM TAF7L 24234451 30021884 physical association cross-linking study IntAct
TUFM PRX 24234451 30021884 physical association cross-linking study IntAct
TUFM MYO5C 24234451 30021884 physical association cross-linking study IntAct
TUFM B3GNT7 24234451 30021884 physical association cross-linking study IntAct
TUFM RABL2B 24234451 30021884 physical association cross-linking study IntAct
TUFM CCNL2 24234451 30021884 physical association cross-linking study IntAct
TUFM VASH1 24234451 30021884 physical association cross-linking study IntAct
L1TD1 TUFM 24234451 25702638 association anti bait coimmunoprecipitation IntAct
TPT1 TUFM 24234451 27607350 association anti bait coimmunoprecipitation IntAct
TUFM NLRX1 22749352 27898060 N/A N/A OmniPath

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