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GENE：MCMBP

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol MCMBP
FullNmae minichromosome maintenance complex binding protein
LocusType gene with protein product
Status Approved
HGNC_id HGNC:25782
EnsembleID ENSG00000197771
Uniprot Q9BTE3

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
MCMBP mitotic_cd 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
MCMBP cuproptosis 36010978 Derived from the genome-wide CRISPR-Cas9 loss-of-function test reported in previous literature, 347 potential cuproptosis-related genes (FDR < 0.05) were identified, and for a detailed list of genes, see聽Supplementary Table S1. Cuproptosis-related genes

Go Annotation:

GeneSymbol Go id
MCMBP GO:0003682,GO:0003682,GO:0005515,GO:0005634,GO:0005654,GO:0005829,GO:0006261,GO:0006261,GO:0007062,GO:0030054,GO:0051301

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
MCMBP MCM7 23180781 24299456 physical association anti tag coimmunoprecipitation,pull down InnateDB
MCMBP MCM6 23180781 24299456 physical association anti tag coimmunoprecipitation,pull down InnateDB
MCMBP MCM2 23180781 24299456 physical association anti tag coimmunoprecipitation InnateDB
MCMBP MCM3 23180781 24299456 physical association anti tag coimmunoprecipitation InnateDB
MCMBP MCM4 23180781 24299456 physical association anti tag coimmunoprecipitation InnateDB
MCMBP MCM5 23180781 24299456 physical association anti tag coimmunoprecipitation InnateDB
MCMBP SMC3 23180781 24299456 physical association anti tag coimmunoprecipitation InnateDB
MCMBP ORC3 23180781 24299456 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
AR MCMBP 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 MCMBP 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
FOXP3 MCMBP 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
SMARCA4 MCMBP 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF MCMBP 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 MCMBP 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 MCMBP 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXP1 MCMBP 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS MCMBP 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 MCMBP 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000007FBA MCMBP 20371350 25416803 mrna cleavage,inhibition nucleotide sequence identification TarBase
URS00000EED18 MCMBP 21566225 25416803 mrna cleavage,inhibition experimental interaction detection TarBase
URS000003ABC4 MCMBP 19088304 25416803 mrna cleavage,inhibition array technology TarBase
URS0000148B91 MCMBP 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000008C563 MCMBP 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00000BE495 MCMBP 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000031B6ED MCMBP 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00002E1509 MCMBP 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS000016FD1B MCMBP 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS000008931A MCMBP 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS00003CCBB9 MCMBP 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS0000250A40 MCMBP 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS000031D186 MCMBP 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS000075994C MCMBP 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS000012930C MCMBP 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS00000AD02D MCMBP 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS0000001EB3 MCMBP 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS000041CB9C MCMBP 19536157 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
ATP6V1D MCMBP 25348397 N/A physical interaction ComPPI
C1QTNF2 MCMBP 25348397 N/A physical interaction ComPPI
RABGGTB MCMBP 25348397 N/A physical interaction ComPPI
MCM5 MCMBP 17296731 22540012 24234451 24299456 25036637 25348397 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,pull down,physical interaction,tandem affinity purification ComPPI,IntAct
KEAP1 MCMBP 19615732 24234451 25036637 25348397 association,physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
MCM6 MCMBP 17296731 22540012 24234451 24299456 25036637 25348397 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,pull down,physical interaction,tandem affinity purification ComPPI,IntAct
MCM2 MCMBP 22540012 24234451 24299456 25036637 25348397 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,cosedimentation through density gradient,physical interaction ComPPI,IntAct
USP7 MCMBP 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
RHPN1 MCMBP 25348397 N/A physical interaction ComPPI
CUL3 MCMBP 25348397 N/A physical interaction ComPPI
MCM10 MCMBP 25348397 N/A physical interaction ComPPI
PFKP MCMBP 25348397 N/A physical interaction ComPPI
NTRK1 MCMBP 25348397 N/A physical interaction ComPPI
STAT5B MCMBP 25348397 N/A physical interaction ComPPI
SUV39H1 MCMBP 25348397 N/A physical interaction ComPPI
YAP1 MCMBP 24234451 24366813 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
SMC3 MCMBP 22540012 24234451 24299456 25348397 association,physical association anti bait coimmunoprecipitation ComPPI,IntAct
CDK16 MCMBP 25348397 N/A physical interaction ComPPI
CDC7 MCMBP 22540012 24234451 24299456 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
XPOT MCMBP 25348397 N/A physical interaction ComPPI
MCM3 MCMBP 17296731 22540012 24234451 24299456 25036637 25348397 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,pull down,physical interaction,tandem affinity purification ComPPI,IntAct
ORC3 MCMBP 24234451 24299456 25348397 association anti bait coimmunoprecipitation ComPPI,IntAct
MCM4 MCMBP 17296731 22540012 24234451 24299456 25036637 25348397 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,cosedimentation,pull down,physical interaction,tandem affinity purification ComPPI,IntAct
ATP6V1A MCMBP 25348397 N/A physical interaction ComPPI
TEAD3 MCMBP 24234451 24366813 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
DDIT3 MCMBP 14525934 16189514 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
TCEAL1 MCMBP 25348397 N/A physical interaction ComPPI
MCM7 MCMBP 17296731 22540012 24234451 24299456 25036637 25348397 25416956 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,pull down,physical interaction,two hybrid array,tandem affinity purification,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
MCM8 MCMBP 22540012 24234451 24299456 25036637 25348397 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
DCAF12 MCMBP 25348397 N/A physical interaction ComPPI
DEFA1 MCMBP 25348397 N/A physical interaction ComPPI
DEFA5 MCMBP 25348397 N/A physical interaction ComPPI
MCMBP TECPR1 20562859 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
MCMBP RPRD1A 25348397 N/A physical interaction ComPPI
MCMBP FKBP5 24234451 25036637 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
MCMBP MCM9 24234451 25036637 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
MCMBP PRTFDC1 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
MCMBP MOV10 25348397 N/A physical interaction ComPPI
MCMBP NXF1 25348397 N/A physical interaction ComPPI
MCMBP MAGIX 25348397 N/A physical interaction ComPPI
MCMBP UNK 25348397 N/A physical interaction ComPPI
MCMBP COMMD2 25348397 N/A physical interaction ComPPI
MCMBP COMMD4 25348397 N/A physical interaction ComPPI
MCMBP LARS1 25348397 N/A physical interaction ComPPI
MCMBP PLCG1 25348397 N/A physical interaction ComPPI
MCMBP TIPRL 25348397 N/A physical interaction ComPPI
MCMBP NPEPL1 25348397 N/A physical interaction ComPPI
MCMBP PHLPP1 25348397 N/A physical interaction ComPPI
MCMBP WDR55 25348397 N/A physical interaction ComPPI
MCMBP TAFA3 25348397 N/A physical interaction ComPPI
MCMBP DHX30 25348397 N/A physical interaction ComPPI
MCMBP TMEM184A 25348397 N/A physical interaction ComPPI
MCMBP DNAAF8 25348397 N/A physical interaction ComPPI
MCMBP GINS4 22540012 24234451 24299456 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
MCMBP KSR1 24234451 25348397 27086506 association anti tag coimmunoprecipitation ComPPI,IntAct
GINS2 MCMBP 22540012 24234451 24299456 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct

Visualization










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